☆ 4.7 Review

Gut Microbial Sialidases and Their Role in the Metabolism of Human Milk Sialylated Glycans

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Review Agriculture, Multidisciplinary

Biosynthesis of Human Milk Oligosaccharides: Enzyme Cascade and Metabolic Engineering Approaches

Jiawei Meng et al.

Summary: Human milk oligosaccharides (HMOs) are considered the new gold standard for premium infant formula due to their unique beneficial effects for infants. HMOs are a collection of unconjugated glycans, with over 200 distinct structures identified. The production of HMOs involves glycosylation using specific glycosyltransferases and nucleotide sugar donors.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2023)

添加到收藏夹

Correction Biochemistry & Molecular Biology

Biochemical and structural basis of sialic acid utilization by gut microbes (vol 299, 104610, 2023)

Andrew Bell et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2023)

添加到收藏夹

Article Food Science & Technology

Cross-feeding among bifidobacteria on glycomacropeptide

Mai Morozumi et al.

Summary: This study investigated the bifidogenic effects of cow's glycomacropeptide (GMP) and metabolic enzymes that Bifidobacterium species use. The results showed that Bifidobacterium bifidum JCM1254 can grow in a medium containing GMP, and the growth is dependent on the presence of glycans. Carbohydrate metabolism-related proteins, including sialidase, were more abundant when Bifidobacterium bifidum JCM1254 was cultured in the GMP-containing medium. Additionally, GMP glycans can be utilized by other bifidobacteria, and the cross-feeding process involves carbohydrate metabolism-related proteins expressed by Bifidobacterium bifidum.

JOURNAL OF FUNCTIONAL FOODS (2023)

添加到收藏夹

Article Multidisciplinary Sciences

Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria

Bashar Shuoker et al.

Summary: This study provides insights into the mechanism of mucin O-glycan degradation by Akkermansia muciniphila and the nutrient sharing between this symbiotic bacteria and the mucus-associated microbiota. They discovered new enzymes involved in the breakdown of protective caps on mucin, which promote the growth of A. muciniphila and the production of butyrate through cooperation with other bacteria.

NATURE COMMUNICATIONS (2023)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Recent progress on health effects and biosynthesis of two key sialylated human milk oligosaccharides, 3′-sialyllactose and 6′-sialyllactose

Yingying Zhu et al.

Summary: Human milk oligosaccharides (HMOs) are recognized as the first prebiotics for health benefits in infants. Sialylated HMOs, including 3'-Sialyllactose (3'-SL) and 6 '-sialyllactose (6'-SL), have promising prebiotic effects and various health benefits. Both SLs have been approved as safe and are added to infant formula.

BIOTECHNOLOGY ADVANCES (2023)

添加到收藏夹

Article Nutrition & Dietetics

Early-life formula feeding is associated with infant gut microbiota alterations and an increased antibiotic resistance load

Katariina M. M. Parnanen et al.

Summary: The study found that early exposure to formula is correlated with a higher neonatal ARG burden, suggesting that feeding mode should be considered by clinicians to minimize the proliferation of antibiotic-resistant gut bacteria in infants, in addition to antibiotic use during the first months of life.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Utilization Efficiency of Human Milk Oligosaccharides by Human-Associated Akkermansia Is Strain Dependent

Estefani Luna et al.

Summary: This study examined the capability of Akkermansia strains to utilize human milk oligosaccharides (HMOs). The results showed that strains representing different phylogroups of Akkermansia had varied metabolic potentials to degrade HMOs and were able to grow on HMOs and produce metabolites. These interactions between Akkermansia and HMOs potentially influence gut microbial ecology in early life, which is critical for the development of the gut microbiome and infant health.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2022)

添加到收藏夹

Review Chemistry, Applied

Review of sialic acid's biochemistry, sources, extraction and functions with special reference to edible bird's nest

Alvin Jin Wei Ling et al.

Summary: Sialic acids, a group of alpha-keto acids with nine carbons, exist in over 50 forms, with sources ranging from edible bird's nests to enzymatic extraction. Recognized for its bioactivities, sialic acid can be utilized as a functional ingredient across various industries.

FOOD CHEMISTRY (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Development of the digestive system in early infancy and nutritional management of digestive problems in breastfed and formula-fed infants

Hanyun Jiang et al.

Summary: Food digestion and absorption play a crucial role in the early growth and long-term health of infants. Due to the immature gastrointestinal tract, infants often experience mild digestive problems such as inefficient digestion and impaired absorption of nutrients. Various types of infant formulas have been developed to address these issues.

FOOD & FUNCTION (2022)

添加到收藏夹

Article Microbiology

Distribution and Evolutionary History of Sialic Acid Catabolism in the Phylum Actinobacteria

Yisong Li et al.

Microbiology Spectrum (2022)

添加到收藏夹

Review Food Science & Technology

Sialic acid, the secret gift for the brain

Fan Liu et al.

Summary: The human brain grows rapidly in early life and requires adequate nutrition, with human milk providing optimal nutrition and breastfeeding improving cognition development. Sialic acid, a key molecule essential for brain development, is found in human milk oligosaccharides (HMOS). Dietary supplementation with sialic acid or sialylated oligosaccharides enhances intelligence and cognition performance. Furthermore, sialic acid is implicated in brain homeostasis and neurodegenerative diseases such as Alzheimer's disease.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2022)

添加到收藏夹

Article Environmental Sciences

O-acetylesterase activity of Bifidobacterium bifidum sialidase facilities the liberation of sialic acid and encourages the proliferation of sialic acid scavenging Bifidobacterium breve

Tatsunari Yokoi et al.

Summary: The esterase activity of the SiaBb1 Est domain enhances the efficiency of SiaBb2 to cleave sialic acid from mucin, facilitating the cross-feeding of sialic acid between Bifidobacterium strains.

ENVIRONMENTAL MICROBIOLOGY REPORTS (2022)

添加到收藏夹

Article Immunology

The Infant Gut Commensal Bacteroides dorei Presents a Generalized Transcriptional Response to Various Human Milk Oligosaccharides

Sivan Kijner et al.

Summary: Human milk oligosaccharides (HMOs) play a crucial role in the infant gut microbiome, benefiting not only Bifidobacterium but also other microbes like Bacteroides. Research reveals variations in HMO utilization across different Bacteroides strains, with B. dorei displaying a comprehensive metabolic response to HMOs, distinct from previously studied Bifidobacterium species.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Structural and functional characterisation of a stable, broad-specificity multimeric sialidase from the oral pathogen Tannerella forsythia

Marianne J Satur et al.

BIOCHEMICAL JOURNAL (2022)

添加到收藏夹

Review Nutrition & Dietetics

Human Milk Microbiome and Microbiome-Related Products: Potential Modulators of Infant Growth

Jie Ma et al.

Summary: Infant growth trajectory may influence later-life obesity, and bioactive components in human milk, such as microbiota, oligosaccharides, fatty acids, and antimicrobial proteins, play a role in infant gut microbiome and metabolism, potentially affecting the development of obesity.

NUTRIENTS (2022)

添加到收藏夹

Review Nutrition & Dietetics

Human Milk Oligosaccharides as Potential Antibiofilm Agents: A Review

Ankurita Bhowmik et al.

Summary: This review summarizes the potential of human milk oligosaccharides (HMOs) as antibacterial and antibiofilm agents, highlighting their prospects in new-age therapeutic interventions.

NUTRIENTS (2022)

添加到收藏夹

Review Microbiology

A systematic review of breast milk microbiota composition and the evidence for transfer to and colonisation of the infant gut

C. A. Edwards et al.

Summary: The composition of the breastmilk microbiota and its transfer to the infant gut were evaluated in a systematic review. The review found that various factors and methods can influence the transfer and colonization of the breastmilk microbiota. However, there is limited evidence for its effective impact on gut colonization in infants.

BENEFICIAL MICROBES (2022)

添加到收藏夹

Article Neurosciences

Altered expression of glycobiology-related genes in Parkinson's disease brain

Jay S. S. Schneider et al.

Summary: The precise mechanisms of cellular degeneration in Parkinson's disease (PD) are still unclear, but altered expression of genes related to gangliosides, glycosylation, sialylation, and sphingolipid synthesis and metabolism may play important roles. This study found abnormal expression of various genes related to glycosyltransferases, sphingosine-1-phosphate modulators, and polysialyltransferases in the brains of PD patients. These findings highlight the complexity of glycolipid/sphingolipid dysregulation in PD and suggest potential targets for PD therapeutics.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2022)

添加到收藏夹

Review Nutrition & Dietetics

Special Diets in Infants and Children and Impact on Gut Microbioma

Elisabetta Di Profio et al.

Summary: The gut microbiota, influenced by multiple factors, plays a crucial role in the development of infants and children. Breastfeeding, complementary feeding, and dietary patterns during infancy and toddlerhood are important for the proper development of the gut microbiota. Dysbiosis can have long-lasting effects, leading to an increased risk of non-communicable diseases, weakened immune system, and alterations in the gut-brain axis. Children with specific diseases require special formulas and diets to exclude certain foods or nutrients. This review aims to examine the impact of special formulas and diets on the gut microbiota and their potential health implications in children.

NUTRIENTS (2022)

添加到收藏夹

Review Nutrition & Dietetics

Milk: A Scientific Model for Diet and Health Research in the 21st Century

J. Bruce German et al.

Summary: The origin, composition, structures, and functions of lactation and milk's biopolymers are important evidence of the Darwinian pressure and selection on lactation as a complete and protective diet. Lactation serves as a sustainable bioreactor with diverse biopolymers that interact with the infant's digestive system from the mammary gland. The interaction between glycan structures in milk and bacteria in the infant's gut has significant health benefits.

FRONTIERS IN NUTRITION (2022)

添加到收藏夹

Review Microbiology

Mother-infant transmission of human microbiota

Hilary P. Browne et al.

Summary: Humans are colonised by a highly adapted microbiota that coevolved to promote human health and disease resistance. Acquisition of these microbiota starts at birth and is linked to immune system development in infants. Disruption of maternal transmission through caesarean section and antibiotic exposure can lead to higher incidence of immune-related disorders in children. Therefore, it is important to prioritize the optimization and nurturing of maternally transmitted microbiota for infants' health.

CURRENT OPINION IN MICROBIOLOGY (2022)

添加到收藏夹

Review Microbiology

Biological functions of sialic acid as a component of bacterial endotoxin

Bartlomiej Dudek et al.

Summary: This review discusses the role of sialic acid in bacterial pathogenesis, its involvement in evading the host immune response, and its significance in bacterial resistance to serum complement. However, many aspects of these phenomena are still unclear.

FRONTIERS IN MICROBIOLOGY (2022)

添加到收藏夹

Article Immunology

Characterization of sialylation-related long noncoding RNAs to develop a novel signature for predicting prognosis, immune landscape, and chemotherapy response in colorectal cancer

Mingxuan Zhou et al.

Summary: This study identified the importance of sialylation-related lncRNAs in the prognosis of colorectal cancer patients and proposed a novel lncRNA signature for accurately evaluating prognosis and exploring potential molecular mechanisms related to sialylation.

FRONTIERS IN IMMUNOLOGY (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Human Gut Metagenomes Encode Diverse GH156 Sialidases

Evan Mann et al.

Summary: The intestinal lining is protected by a mucous barrier primarily composed of complex carbohydrates. Gut microbes use a variety of glycoside hydrolases to break down mucosal sugars, facilitating host colonization, but excessive breakdown may lead to barrier erosion, pathogen invasion, and inflammation. Sialidases from the microbiome, specifically the GH156 family, play a crucial role in human microbiomes, with potential therapeutic applications in cancer therapy. However, the full extent of GH156 sialidases and their functions in the human gut environment are still being explored.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Recent advances on human milk oligosaccharide antimicrobial activity

Sabrina K. Spicer et al.

Summary: This short review focuses on the antimicrobial properties of human breast milk, particularly with an emphasis on human milk oligosaccharides (HMOs), and highlights the importance of HMOs in promoting human health.

CURRENT OPINION IN CHEMICAL BIOLOGY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

The N-glycans of lactoferrin: more than just a sweet decoration

Kristina Zlatina et al.

Summary: Most extracellular proteins undergo sugar chain post-translational modification, which not only affects the activity of carrier proteins but also has bioactivity on its own. The diverse glycosylation patterns of lactoferrin from different sources and their impact on functionality are discussed in this review, with a focus on the differences between human and bovine lactoferrin and their potential effects on therapeutic approaches.

BIOCHEMISTRY AND CELL BIOLOGY (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Engineering the Sialome

Landon J. Edgar

Summary: The review discusses strategies for altering the composition of cellular sialic acids (sialome), with a focus on glycan structures and state-of-the-art tools.

ACS CHEMICAL BIOLOGY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Monitoring Human Milk β-Casein Phosphorylation and O-Glycosylation Over Lactation Reveals Distinct Differences between the Proteome and Endogenous Peptidome

Kelly A. Dingess et al.

Summary: Human milk contains beta-casein, a protein that undergoes post-translational modifications such as phosphorylation and glycosylation. A study observed changes in phosphorylation and previously unexplored O-glycosylation of beta-casein in two donors over 16 weeks of lactation, indicating the importance of these modifications on antimicrobial peptides derived from beta-casein.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Review Gastroenterology & Hepatology

Carbohydrates great and small, from dietary fiber to sialic acids: How glycans influence the gut microbiome and affect human health

Joanna K. Coker et al.

Summary: The composition of gut microbiome is heavily influenced by diet, particularly dietary carbohydrates. Carbohydrates can shape the gut microbiome by providing nutrients to specific microbes, with varying effects on host health. Sialic acids, a type of monosaccharide, have significant impact on the gut microbiota.

GUT MICROBES (2021)

添加到收藏夹

Article Food Science & Technology

Production of functional mimics of human milk oligosaccharides by enzymatic glycosylation of bovine milk oligosaccharides

Valerie Weinborn et al.

INTERNATIONAL DAIRY JOURNAL (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Diversity of sialidases found in the human body - A review

Sabina Lipnicanova et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Review Nutrition & Dietetics

Breast Milk, a Source of Beneficial Microbes and Associated Benefits for Infant Health

Katriona E. Lyons et al.

NUTRIENTS (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Synthesis of Human Milk Oligosaccharides: Protein Engineering Strategies for Improved Enzymatic Transglycosylation

Birgitte Zeuner et al.

MOLECULES (2019)

添加到收藏夹

Article Microbiology

Nontypeable Haemophilus influenzae Has Evolved Preferential Use of N-Acetylneuraminic Acid as a Host Adaptation

Preston S. K. Ng et al.

MBIO (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

Sialic acid metabolism as a potential therapeutic target of atherosclerosis

Chao Zhang et al.

LIPIDS IN HEALTH AND DISEASE (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action

Pedro Bule et al.

NATURE COMMUNICATIONS (2019)

添加到收藏夹

Article Microbiology

Two extracellular sialidases from Bifidobacterium bifidum promote the degradation of sialyl-oligosaccharides and support the growth of Bifidobacterium breve

Keita Nishiyama et al.

ANAEROBE (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Bifunctional properties and characterization of a novel sialidase with esterase activity from Bifidobacterium bifidum

Hisashi Ashida et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2018)

添加到收藏夹

Review Biochemistry & Molecular Biology

Serum sialylation changes in cancer

Zejian Zhang et al.

GLYCOCONJUGATE JOURNAL (2018)

添加到收藏夹

Review Medicine, Research & Experimental

Evolution of sialic acids: Implications in xenotransplant biology

Anu Paul et al.

XENOTRANSPLANTATION (2018)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Enzymatic Synthesis of 6 '-Sialyllactose, a Dominant Sialylated Human Milk Oligosaccharide, by a Novel exo-alpha-Sialidase from Bacteroides fragilis NCTC9343

Longcheng Guo et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2018)

添加到收藏夹

Review Pharmacology & Pharmacy

Diagnostics and Therapy of Human Diseases - Focus on Sialidases

V. P. Karagodin et al.

CURRENT PHARMACEUTICAL DESIGN (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Functional metagenomics identifies an exosialidase with an inverting catalytic mechanism that defines a new glycoside hydrolase family (GH156)

Lea Chuzel et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

添加到收藏夹

Article Nutrition & Dietetics

Milk Oligosaccharides Inhibit Human Rotavirus Infectivity in MA104 Cells

Daniel R. Laucirica et al.

JOURNAL OF NUTRITION (2017)

添加到收藏夹

Review Nutrition & Dietetics

Systematic review of the concentrations of oligosaccharides in human milk

Stephan Thurl et al.

NUTRITION REVIEWS (2017)

添加到收藏夹

Review Oncology

Sialylation: an Avenue to Target Cancer Cells

Bhairavi N. Vajaria et al.

PATHOLOGY & ONCOLOGY RESEARCH (2016)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Aberrant sialylation causes dilated cardiomyopathy and stress-induced heart failure

Wei Deng et al.

BASIC RESEARCH IN CARDIOLOGY (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Characterization of a high-affinity sialic acid-specific CBM40 from Clostridium perfringens and engineering of a divalent form

Joao P. Ribeiro et al.

BIOCHEMICAL JOURNAL (2016)

添加到收藏夹

Article Agriculture, Multidisciplinary

Evaluation of Sialic Acid in Infant Feeding: Contents and Bioavailability

Lorena Claumarchirant et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2016)

添加到收藏夹

Article Multidisciplinary Sciences

It All Starts with a Sandwich: Identification of Sialidases with Trans-Glycosylation Activity

Rune T. Nordvang et al.

PLOS ONE (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Biochemical characterisation of the neuraminidase pool of the human gut symbiont Akkermansia muciniphila

Kun Huang et al.

CARBOHYDRATE RESEARCH (2015)

添加到收藏夹

Article Multidisciplinary Sciences

Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation

Louise E. Tailford et al.

NATURE COMMUNICATIONS (2015)

添加到收藏夹

Article Multidisciplinary Sciences

Sialic acid catabolism drives intestinal inflammation and microbial dysbiosis in mice

Yen-Lin Huang et al.

NATURE COMMUNICATIONS (2015)

添加到收藏夹

Article Biochemical Research Methods

Human Milk Glycomics and Gut Microbial Genomics in Infant Feces Show a Correlation between Human Milk Oligosaccharides and Gut Microbiota: A Proof-of-Concept Study

Maria Lorna A. De Leoz et al.

JOURNAL OF PROTEOME RESEARCH (2015)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Metabolism of Sialic Acid by Bifidobacterium breve UCC2003

Muireann Egan et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2014)

添加到收藏夹

Article Biochemical Research Methods

Hydrolysis of milk gangliosides by infant-gut associated bifidobacteria determined by microfluidic chips and high-resolution mass spectrometry

Hyeyoung Lee et al.

ELECTROPHORESIS (2014)

添加到收藏夹

Review Biochemistry & Molecular Biology

The interplay between Siglecs and sialylated pathogens

Yung-Chi Chang et al.

GLYCOBIOLOGY (2014)

添加到收藏夹

Review Agriculture, Multidisciplinary

Methods for Improving Enzymatic Trans-glycosylation for Synthesis of Human Milk Oligosaccharide Biomimetics

Birgitte Zeuner et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2014)

添加到收藏夹

Article Biochemistry & Molecular Biology

Structural and biochemical characterization of the broad substrate specificity of Bacteroides thetaiotaomicron commensal sialidase

Kwang-Hyun Park et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Utilization of major fucosylated and sialylated human milk oligosaccharides by isolated human gut microbes

Zhuo-Teng Yu et al.

GLYCOBIOLOGY (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

A surface-exposed neuraminidase affects complement resistance and virulence of the oral spirochaete Treponema denticola

Kurni Kurniyati et al.

MOLECULAR MICROBIOLOGY (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Insights into the recognition of the human glycome by microbial carbohydrate-binding modules

Elizabeth Ficko-Blean et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2012)

添加到收藏夹

Article Obstetrics & Gynecology

Association of complex lipids containing gangliosides with cognitive development of 6-month-old infants

Dida A. Gurnida et al.

EARLY HUMAN DEVELOPMENT (2012)

添加到收藏夹

Article Biochemical Research Methods

Comprehensive Profiles of Human Milk Oligosaccharides Yield Highly Sensitive and Specific Markers for Determining Secretor Status in Lactating Mothers

Sarah M. Totten et al.

JOURNAL OF PROTEOME RESEARCH (2012)

添加到收藏夹

Article Microbiology

Bacteroides in the Infant Gut Consume Milk Oligosaccharides via Mucus-Utilization Pathways

Angela Marcobal et al.

CELL HOST & MICROBE (2011)

添加到收藏夹

Article Biochemistry & Molecular Biology

An exo-α-sialidase from bifidobacteria involved in the degradation of sialyloligosaccharides in human milk and intestinal glycoconjugates

Masashi Kiyohara et al.

GLYCOBIOLOGY (2011)

添加到收藏夹

Article Biochemistry & Molecular Biology

An Infant-associated Bacterial Commensal Utilizes Breast Milk Sialyloligosaccharides

David A. Sela et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

添加到收藏夹

Article Biotechnology & Applied Microbiology

The Sialome-Far More Than the Sum of Its Parts

Miriam Cohen et al.

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2010)

添加到收藏夹

Article Biochemistry & Molecular Biology

Crystal structures of respiratory pathogen neuraminidases

Yu-Shan Hsiao et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)

添加到收藏夹

Review Biochemistry & Molecular Biology

Sialic acids as regulators of molecular and cellular interactions

Roland Schauer

CURRENT OPINION IN STRUCTURAL BIOLOGY (2009)

添加到收藏夹

Article Biochemistry & Molecular Biology

Structural Studies on the Pseudomonas aeruginosa Sialidase-Like Enzyme PA2794 Suggest Substrate and Mechanistic Variations

Guogang Xu et al.

JOURNAL OF MOLECULAR BIOLOGY (2009)

添加到收藏夹

Article Biochemistry & Molecular Biology

Carbohydrate recognition by a large sialidase toxin from Clostridium perfringenis

Alisdair B. Boraston et al.

BIOCHEMISTRY (2007)

添加到收藏夹

Article Pediatrics

Human milk oligosaccharides inhibit the adhesion to Caco-2 cells of diarrheal pathogens:: Escherichia coli, Vibrio cholerae, and Salmonella fyris

GV Coppa et al.

PEDIATRIC RESEARCH (2006)

添加到收藏夹

Article Biochemical Research Methods

Crystallization and atomic resolution X-ray diffraction of the catalytic domain of the large sialidase, nanI, from Clostridium perfringens

S Newstead et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)

添加到收藏夹

Article Multidisciplinary Sciences

Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media

V Bouchet et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

添加到收藏夹

Article Biochemistry & Molecular Biology

Redirection of sialic acid metabolism in genetically engineered Escherichia coli

M Ringenberg et al.

GLYCOBIOLOGY (2001)

添加到收藏夹

Article Chemistry, Organic

Chemoenzymatic synthesis of sialyl oligosaccharides with sialidases employing transglycosylation methodology

D Schmidt et al.

JOURNAL OF ORGANIC CHEMISTRY (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.