Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage

Aneurysmal subarachnoid hemorrhage (aSAH) is one of the most severe neurological disorders, with a high mortality rate and severe disabling functional sequelae. Systemic inflammation following hemorrhagic stroke may play an important role in mediating intracranial and extracranial tissue damage. Previous studies showed that various systemic inflammatory biomarkers might be useful in predicting clinical outcomes. Anti-inflammatory treatment might be a promising therapeutic approach for improving the prognosis of patients with aSAH. This review summarizes the complicated interactions between the nervous system and the immune system.

Automated summary

Aneurysmal subarachnoid hemorrhage (aSAH) is a severe neurological disorder with high mortality and severe functional sequelae. Systemic inflammation after hemorrhagic stroke may contribute to intracranial and extracranial tissue damage. Previous studies suggest that systemic inflammatory biomarkers could be useful in predicting clinical outcomes. Anti-inflammatory treatment may hold promise in improving prognosis for patients with aSAH. This review summarizes the intricate interactions between the nervous and immune systems.