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MICROORGANISMS (2023)
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INTERNATIONAL JOURNAL FOR PARASITOLOGY (2022)
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
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Journal of Parasitic Diseases (2022)
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MICROBIOLOGICAL RESEARCH (2022)
Exosomes secreted by Blastocystis subtypes affect the expression of proinflammatory and anti-inflammatory cytokines (TNFα, IL-6, IL-10, IL-4)
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FRONTIERS IN MEDICINE (2022)
Immunomodulatory effect of extracellular vesicles from Entamoeba histolytica trophozoites: Regulation of NETs and respiratory burst during confrontation with human neutrophils
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FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2022)
Association of Blastocystis ST6 with higher protease activity among symptomatic subjects
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BMC MICROBIOLOGY (2021)
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BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2021)
The Coexistence of Blastocystis spp. in Humans, Animals and Environmental Sources from 2010-2021 in Asia
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BIOLOGY-BASEL (2021)
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MICROBIOLOGICAL RESEARCH (2021)
Giardia duodenalis Virulence - To Be, or Not To Be
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CURRENT TROPICAL MEDICINE REPORTS (2021)
Inhibition of Amebic Cysteine Proteases Blocks Amebic Trogocytosis but Not Phagocytosis
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JOURNAL OF INFECTIOUS DISEASES (2020)
The Biology of the Intestinal Intracellular Parasite Cryptosporidium
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CELL HOST & MICROBE (2020)
Peptidylarginine Deiminase Inhibition Abolishes the Production of Large Extracellular Vesicles FromGiardia intestinalis, Affecting Host-Pathogen Interactions by Hindering Adhesion to Host Cells
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FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2020)
Giardia intestinalis cystatin is a potent inhibitor of papain, parasite cysteine proteases and, to a lesser extent, human cathepsin B
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FEBS LETTERS (2019)
Cleavage specificity of recombinant Giardia intestinalis cysteine proteases: Degradation of immunoglobulins and defensins
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MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2019)
Entamoeba histolytica Cyclooxygenase-Like Protein Regulates Cysteine Protease Expression and Virulence
Preeti Shahi et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2019)
The MEROPS database of proteolytic enzymes, their substrates and inhibitors in 2017 and a comparison with peptidases in the PANTHER database
Neil D. Rawlings et al.
NUCLEIC ACIDS RESEARCH (2018)
Genetic diversity and pathogenicity of Blastocystis
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ANNALS OF AGRICULTURAL AND ENVIRONMENTAL MEDICINE (2018)
Giardipain-1, a protease secreted by Giardia duodenalis trophozoites, causes junctional, barrier and apoptotic damage in epithelial cell monolayers
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INTERNATIONAL JOURNAL FOR PARASITOLOGY (2018)
Two key cathepsins, TgCPB and TgCPL, are targeted by the vinyl sulfone inhibitor K11777 in in vitro and in vivo models of toxoplasmosis
Juan D. Chaparro et al.
PLOS ONE (2018)
Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines
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VIRULENCE (2018)
Giardia secretome highlights secreted tenascins as a key component of pathogenesis
Audrey Dubourg et al.
GIGASCIENCE (2018)
Iron-modulated virulence factors of Entamoeba histolytica
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FUTURE MICROBIOLOGY (2018)
Cysteine proteases in protozoan parasites
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PLOS NEGLECTED TROPICAL DISEASES (2018)
Is the genetic variability of Cathepsin B important in the pathogenesis of Blastocystis spp.?
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PARASITOLOGY RESEARCH (2018)
Activity of Thioallyl Compounds From Garlic Against Giardia duodenalis Trophozoites and in Experimental Giardiasis
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FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2018)
Expression and secretion of the Giardia duodenalis variant surface protein 9B10A by transfected trophozoites causes damage to epithelial cell monolayers mediated by protease activity
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EXPERIMENTAL PARASITOLOGY (2017)
Giardia duodenalis induces pathogenic dysbiosis of human intestinal microbiota biofilms
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INTERNATIONAL JOURNAL FOR PARASITOLOGY (2017)
Extreme genome diversity in the hyper-prevalent parasitic eukaryote Blastocystis
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PLOS BIOLOGY (2017)
Characterization of the Giardia intestinalis secretome during interaction with human intestinal epithelial cells: The impact on host cells
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PLOS NEGLECTED TROPICAL DISEASES (2017)
Entamoeba histolytica EhCP112 Dislocates and Degrades Claudin-1 and Claudin-2 at Tight Junctions of the Intestinal Epithelium
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FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2017)
Revealing a Novel Otubain-Like Enzyme from Leishmania infantum with Deubiquitinating Activity toward K48-Linked Substrate
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FRONTIERS IN CHEMISTRY (2017)
Adherens junctions and desmosomes are damaged by Entamoeba histolytica: Participation of EhCPADH complex and EhCP112 protease
Elizabeth Hernandez-Nava et al.
CELLULAR MICROBIOLOGY (2017)
Interactions of Giardia sp. with the intestinal barrier: Epithelium, mucus, and microbiota
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TISSUE BARRIERS (2017)
The Microbiota Contributes to CD8+ T Cell Activation and Nutrient Malabsorption following Intestinal Infection with Giardia duodenalis
Aleksander Keselman et al.
INFECTION AND IMMUNITY (2016)
On Blastocystis secreted cysteine proteases: a legumain-activated cathepsin B increases paracellular permeability of intestinal Caco-2 cell monolayers
C. Nourrisson et al.
PARASITOLOGY (2016)
Induction of virulence factors in Giardia duodenalis independent of host attachment
Samantha J. Emery et al.
SCIENTIFIC REPORTS (2016)
Entamoeba histolytica Cysteine Proteinase 5 Evokes Mucin Exocytosis from Colonic Goblet Cells via αvβ3 Integrin
Steve Cornick et al.
PLOS PATHOGENS (2016)
Immunological aspects of intestinal mucus and mucins
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NATURE REVIEWS IMMUNOLOGY (2016)
Molecular and functional characterisation of a stress responsive cysteine protease, EhCP6 from Entamoeba histolytica
Anupama Ghosh et al.
PROTEIN EXPRESSION AND PURIFICATION (2015)
Immunization with the Entamoeba histolytica Surface Metalloprotease EhMSP-1 Protects Hamsters from Amebic Liver Abscess
Eduardo C. Roncolato et al.
INFECTION AND IMMUNITY (2015)
Giardia duodenalis Surface Cysteine Proteases Induce Cleavage of the Intestinal Epithelial Cytoskeletal Protein Villin via Myosin Light Chain Kinase
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PLOS ONE (2015)
The Evolution of Respiratory Cryptosporidiosis: Evidence for Transmission by Inhalation
Jerlyn K. Sponseller et al.
CLINICAL MICROBIOLOGY REVIEWS (2014)
Giardia duodenalis Cathepsin B Proteases Degrade Intestinal Epithelial Interleukin-8 and Attenuate Interleukin-8-Induced Neutrophil Chemotaxis
James A. Cotton et al.
INFECTION AND IMMUNITY (2014)
Differential Regulation of Proinflammatory Cytokine Expression by Mitogen-Activated Protein Kinases in Macrophages in Response to Intestinal Parasite Infection
Mei Xing Lim et al.
INFECTION AND IMMUNITY (2014)
Blastocystis subtypes detected in humans and animals from Colombia
Juan David Ramirez et al.
INFECTION GENETICS AND EVOLUTION (2014)
Ligand heterogeneity of the cysteine protease binding protein family in the parasitic protist Entamoeba histolytica
Konomi Marumo et al.
INTERNATIONAL JOURNAL FOR PARASITOLOGY (2014)
MEROPS: the database of proteolytic enzymes, their substrates and inhibitors
Neil D. Rawlings et al.
NUCLEIC ACIDS RESEARCH (2014)
Characterization of a novel otubain-like cysteine protease of Cryptosporidium parvum
Hye-Lim Ju et al.
PARASITOLOGY INTERNATIONAL (2014)
Update on the pathogenic potential and treatment options for Blastocystis sp
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GUT PATHOGENS (2014)
Intra-Subtype Variation in Enteroadhesion Accounts for Differences in Epithelial Barrier Disruption and Is Associated with Metronidazole Resistance in Blastocystis Subtype-7
Zhaona Wu et al.
PLOS NEGLECTED TROPICAL DISEASES (2014)
Entamoeba histolytica-secreted cysteine proteases induce IL-8 production in human mast cells via a PAR2-independent mechanism
Young Ah Lee et al.
PARASITE (2014)
A Cysteine Protease Inhibitor Rescues Mice from a Lethal Cryptosporidium parvum Infection
Momar Ndao et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)
Genetic Diversity of Blastocystis in Livestock and Zoo Animals
Mohammed A. Alfellani et al.
PROTIST (2013)
Blastocystis: getting to grips with our guileful guest
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TRENDS IN PARASITOLOGY (2013)
Overexpression of Specific Cysteine Peptidases Confers Pathogenicity to a Nonpathogenic Entamoeba histolytica Clone
Jenny Matthiesen et al.
MBIO (2013)
A novel class of cysteine protease receptors that mediate lysosomal transport
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CELLULAR MICROBIOLOGY (2012)
Newly visualized fibrillar collagen scaffolds dictate Entamoeba histolytica invasion route in the human colon
Roman Thibeaux et al.
CELLULAR MICROBIOLOGY (2012)
Representational difference analysis identifies specific genes in the interaction of Giardia duodenalis with the murine intestinal epithelial cell line, IEC-6
Showgy Yasir Ma'ayeh et al.
INTERNATIONAL JOURNAL FOR PARASITOLOGY (2012)
Anoikis potential of Entameba histolytica secretory cysteine proteases: Evidence of contact independent host cell death
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MICROBIAL PATHOGENESIS (2012)
Cryptostatin, a chagasin-family cysteine protease inhibitor of Cryptosporidium parvum
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PARASITOLOGY (2012)
Characterization of two cysteine proteases secreted by Blastocystis ST7, a human intestinal parasite
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PARASITOLOGY INTERNATIONAL (2012)
Cure of Hookworm Infection with a Cysteine Protease Inhibitor
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PLOS NEGLECTED TROPICAL DISEASES (2012)
Transcriptional changes in Giardia during host-parasite interactions
Emma Ringqvist et al.
INTERNATIONAL JOURNAL FOR PARASITOLOGY (2011)
Proteaese activity of Blastocystis hominis subtype3 in symptomatic and asymptomatic patients
Dina Marie Abdel-Hameed et al.
PARASITOLOGY RESEARCH (2011)
Genome sequence of the stramenopile Blastocystis, a human anaerobic parasite
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GENOME BIOLOGY (2011)
Entamoeba histolytica Infection and Secreted Proteins Proteolytically Damage Enteric Neurons
Sandra Lourenssen et al.
INFECTION AND IMMUNITY (2010)
A Novel Entamoeba histolytica Cysteine Proteinase, EhCP4, Is Key for Invasive Amebiasis and a Therapeutic Target
Chen He et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Entamoeba histolytica Cysteine Proteinase 5 Binds Integrin on Colonic Cells and Stimulates NFκB-mediated Pro-inflammatory Responses
Yongzhong Hou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Comparison of Methods for Detection of Blastocystis Infection in Routinely Submitted Stool Samples, and also in IBS/IBD Patients in Ankara, Turkey
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PLOS ONE (2010)
Human Amebiasis: Breaking the Paradigm?
Cecilia Ximenez et al.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2010)
Major cysteine peptidases of Entamoeba histolytica are required for aggregation and digestion of erythrocytes but are dispensable for phagocytosis and cytopathogenicity
Henriette Irmer et al.
MOLECULAR MICROBIOLOGY (2009)
Two approaches to discovering and developing new drugs for Chagas disease
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MEMORIAS DO INSTITUTO OSWALDO CRUZ (2009)
Cryptopain-1, a cysteine protease of Cryptosporidium parvum, does not require the pro-domain for folding
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PARASITOLOGY (2009)
Blastocystis exhibits inter- and intra-subtype variation in cysteine protease activity
Haris Mirza et al.
PARASITOLOGY RESEARCH (2009)
Expression of interferon gamma and proinflammatory cytokines in the cecal mucosa of rats experimentally infected with Blastocystis sp strain RN94-9
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PARASITOLOGY RESEARCH (2009)
Acute urticaria associated with amoeboid forms of Blastocystis sp subtype 3
Alexandra Katsarou-Katsari et al.
ACTA DERMATO-VENEREOLOGICA (2008)
Degradation of human secretory IgA1 and IgA2 by Entamoeba histolytica surface-associated proteolytic activity
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PARASITOLOGY INTERNATIONAL (2008)
Blastocystis ratti contains cysteine proteases that mediate interleukin-8 response from human intestinal epithelial cells in an NF-κB-dependent manner
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EUKARYOTIC CELL (2008)
Use of recombinant Entamoeba histolytica cysteine proteinase I to identify a potent inhibitor of amebic invasion in a human colonic model
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EUKARYOTIC CELL (2007)
Effect of chronic Giardia lamblia infection on epithelial transport and barrier function in human duodenum
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GUT (2007)
Proteinase inhibitors and helminth parasite infection
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PARASITE IMMUNOLOGY (2007)
Terminology for Blastocystis subtypes - a consensus
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TRENDS IN PARASITOLOGY (2007)
Rab11B small GTPase regulates secretion of cysteine proteases in the enteric protozoan parasite Entamoeba histolytica
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CELLULAR MICROBIOLOGY (2007)
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PARASITOLOGY RESEARCH (2006)
Increased expression of the major cysteine proteinases by stable episomal transfection underlines the important role of EhCP5 for the pathogenicity of Entamoeba histolytica
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MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2006)
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PARASITOLOGY RESEARCH (2006)
Giardia and Cryptosporidium join the 'Neglected Diseases Initiative'
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TRENDS IN PARASITOLOGY (2006)
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GASTROENTEROLOGY (2006)
Giardia lamblia-induced changes in gene expression in differentiated Caco-2 human intestinal epithelial cells
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INFECTION AND IMMUNITY (2005)
Degradation of human secretory immunoglobulin A by Blastocystis
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PARASITOLOGY RESEARCH (2005)
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MOLECULAR BIOLOGY OF THE CELL (2005)
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EXPERIMENTAL PARASITOLOGY (2005)
Complete genome sequence of the apicomplexan, Cryptosporidium parvum
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SCIENCE (2004)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
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EXPERIMENTAL AND MOLECULAR PATHOLOGY (2004)
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PARASITE IMMUNOLOGY (2004)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The intestinal protozoan parasite Entamoeba histolytica contains 20 cysteine protease genes, of which only a small subset is expressed during in vitro cultivation
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EUKARYOTIC CELL (2003)
Amebic cysteine proteinase 2 (EhCP2) plays either a minor or no role in tissue damage in acute experimental amebic liver abscess in hamsters
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PARASITOLOGY RESEARCH (2003)
A surface amebic cysteine proteinase inactivates interleukin-18
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INFECTION AND IMMUNITY (2003)
Entamoeba histolytica cysteine proteinases disrupt the polymeric structure of colonic mucin and alter its protective function
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INFECTION AND IMMUNITY (2003)
Protease activity in Giardia duodenalis trophozoites of axenic strains isolated from symptomatic and asymptomatic patients
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MEMORIAS DO INSTITUTO OSWALDO CRUZ (2003)
Host adaptation and host-parasite co-evolution in Cryptosporidium:: implications for taxonomy and public health
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INTERNATIONAL JOURNAL FOR PARASITOLOGY (2002)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
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PROTEIN EXPRESSION AND PURIFICATION (2002)
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MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2002)
Differential gene expression by iron-limitation in Entamoeba histolytica
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MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2001)
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CELLULAR MICROBIOLOGY (2001)
Entamoeba histolytica cysteine proteinases with interleukin-1 beta converting enzyme (ICE) activity cause intestinal inflammation and tissue damage in amoebiasis
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MOLECULAR MICROBIOLOGY (2000)
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