4.7 Article

Studying the Interaction between Bendamustine and DNA Molecule with SERS Based on AuNPs/ZnCl2/NpAA Solid-State Substrate

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Spectroscopy

Raman spectroscopy for the quantitative analysis of Lornoxicam in solid dosage forms

Sammia Aymen et al.

Summary: This study utilized Raman spectroscopy to analyze different formulations of Lornoxicam, a nonsteroidal anti-inflammatory drug, for qualitative and quantitative purposes. The Raman spectral features associated with the drug and excipients were identified and analyzed using chemometric tools like PCA and PLSR. These analyses allowed for differentiation between different groups of Raman spectral data and the development of a prediction model with high accuracy. The application of Raman spectroscopy, PCA, and PLSR analyses proved valuable in determining the concentration of Lornoxicam in pharmaceutical samples.

JOURNAL OF RAMAN SPECTROSCOPY (2023)

Article Chemistry, Multidisciplinary

Nanomolar Binding of an Antibiotic Peptide to DNA Measured with Raman Spectroscopy

Grant J. Myres et al.

Summary: Immobilizing DNA to surfaces is useful for screening small-molecule therapeutic candidates, and this study introduces a method using confocal Raman microscopy to analyze the binding of an antimicrobial peptide, netropsin, to DNA sequences immobilized on porous silica particles. The selectivity study showed that netropsin binds to AT-rich regions of duplex DNA, while the binding affinities were quantified using different concentrations of netropsin solution. The interaction between netropsin and DNA was accompanied by changes in vibrational modes, and the Raman spectrum of netropsin with a control sequence lacking the AT-rich recognition region showed less constrained conformations compared to the specific binding interactions with AT-rich sequences.

LANGMUIR (2023)

Article Optics

Reflection Interference Spectroscopy Technology Monitoring the Synthesis of ZnCl2-ZnO Nanosheets on Nanoporous Anodic Alumina Substrate in Real Time

Ziyi Gong et al.

Summary: In situ, real-time, and non-destructive monitoring of nanomaterial synthesis is essential for the development and application of nanoscience and nanotechnology. Reflection interference spectroscopy technology was used to systematically monitor the synthesis process of a transparent (ZnCl2-ZnO)/NpAA composite film. By analyzing the curve of effective optical thickness with time, it was found that the synthesis process of ZnCl2-ZnO can be divided into three stages. Furthermore, films produced from ZnCl2 precursor solutions with different concentrations can be distinguished based on the characteristics of these three stages.

PHOTONICS (2023)

Article Chemistry, Physical

Spectroscopic, quantum mechanical, electronic excitation properties (Ethanol solvent), DFT investigations and molecular docking analysis of an anti-cancer drug Bendamustine

P. Venkata Ramana et al.

Summary: The investigation focuses on the optimization geometry, spectra analysis, vibrational frequencies, and molecular interactions of Bendamustine, an anti-cancer drug. DFT/B3LYP calculations were used to model the spectra and analyze the properties of the molecule. The study provides valuable insights into the stability and reactivity of the drug.

JOURNAL OF MOLECULAR STRUCTURE (2022)

Article Nanoscience & Nanotechnology

Acoustofluidics for simultaneous nanoparticle-based drug loading and exosome encapsulation

Zeyu Wang et al.

Summary: Researchers have developed an acoustofluidic device that enables simultaneous drug loading and exosome encapsulation. This device utilizes acoustic forces to concentrate and fuse drugs and nanoparticles, resulting in drug-loaded silica nanocarriers encased within an exosomal membrane. The drug loading efficiency is significantly improved, and the process can be completed within minutes, without the need for complex chemical modification.

MICROSYSTEMS & NANOENGINEERING (2022)

Article Chemistry, Analytical

The Mechanism of Dynamic Interaction between Doxorubicin and Calf Thymus DNA at the Single-Molecule Level Based on Confocal Raman Spectroscopy

Ruihong Zhang et al.

Summary: The interaction between doxorubicin (DOX) and DNA molecules, particularly the binding sites and dynamic process, have been systematically investigated using Confocal Raman spectroscopy. The study found that DOX can interact with all four bases of DNA molecules and affect their conformation. The binding site of DOX and its derivatives is also determined. Additionally, the interaction between DOX and DNA molecules is a dynamic process, as evidenced by the regularly changing intensities of characteristic peaks of each base. A dynamic mechanism model of this interaction is proposed, which involves the formation of a complex between DOX and DNA, as well as multimer formation between DOX molecules. This research is important for understanding and developing new drugs and pathways to mitigate DOX-induced cytotoxicity and cardiotoxicity.

MICROMACHINES (2022)

Article Chemistry, Multidisciplinary

A recyclable graphene/Ag/TiO2 SERS substrate with high stability and reproducibility for detection of dye molecules

Zezhou Wang et al.

Summary: In this study, a multi-layer composite SERS substrate was successfully prepared, which exhibited high sensitivity, stability, and reproducibility due to the passivation of graphene, the SERS function of silver, and the photocatalytic activity of titanium dioxide. The substrate can estimate the concentration of probe molecules and has potential applications as an ultra-sensitive, highly stable, and reusable analytical tool.

NEW JOURNAL OF CHEMISTRY (2022)

Article Biochemistry & Molecular Biology

The Use Of Molecular Docking And Spectroscopic Methods For Investigation Of The Interaction Between Regorafenib With Human Serum Albumin (HSA) And Calf Thymus DNA (Ct-DNA) In The Presence Of Different Site Markers

Hamid Tanzadehpanah et al.

Summary: This study investigated the interaction of the anticancer drug regorafenib (REG) with DNA and HSA, revealing that REG primarily acts through hydrophobic interactions in the DNA-REG complex.

PROTEIN AND PEPTIDE LETTERS (2021)

Article Chemistry, Multidisciplinary

A Stable NanoPAA-ZnO/ZnCl2 Composite with Variable 3D Structured Morphology and Sustained Superhydrophilicity

Yukun Zhou et al.

Summary: A ZnO/ZnCl2 composite with stable 3D structural morphologies and long lasting superhydrophilicity was synthesized on a nanoPAA substrate. The water contact angle of the composite could be maintained at 0 degrees for 7 days and remained low even after 50 days. The superhydrophilicity mechanism was attributed to the properties of the ZnO/ZnCl2 nanofilm, wrinkled nanoflakes, nanogaps, and structural morphologies.

LANGMUIR (2021)

Review Chemistry, Multidisciplinary

Nucleic Acid Tests for Clinical Translation

Min Li et al.

Summary: Nucleic acids, such as DNA and RNA, play crucial roles in storing, transmitting, and expressing genetic information. Nucleic acid tests are essential for clinical diagnosis and infectious disease prevention, and have made significant advancements in recent years.

CHEMICAL REVIEWS (2021)

Article Multidisciplinary Sciences

HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation

Marcin J. Suskiewicz et al.

NATURE (2020)

Article Biochemistry & Molecular Biology

Interaction of an abiraterone with calf thymus DNA: Investigation with spectroscopic technique and modelling studies

Tanveer A. Wani et al.

BIOORGANIC CHEMISTRY (2020)

Article Spectroscopy

Validation of SERS enhancement factor measurements

R. Pilot et al.

JOURNAL OF RAMAN SPECTROSCOPY (2018)

Review Chemistry, Multidisciplinary

Surface-Enhanced Raman Spectroscopy for Bioanalysis: Reliability and Challenges

Cheng Zong et al.

CHEMICAL REVIEWS (2018)

Review Biochemistry & Molecular Biology

The discovery of hydrogen bonds in DNA and a re-evaluation of the 1948 Creeth two-chain model for its structure

Stephen E. Harding et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2018)

Article Chemistry, Multidisciplinary

Raman Spectroscopy Reveals Selective Interactions of Cytochrome c with Cardiolipin That Correlate with Membrane Permeability

Jay P. Kitt et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Review Biochemistry & Molecular Biology

Studying non-covalent drug-DNA interactions

Sayeed Ur Rehman et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2015)

Article Biochemistry & Molecular Biology

SERS as an advanced tool for investigating chloroethyl nitrosourea derivatives complexation with DNA

Shweta Agarwal et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2015)

Article Biochemistry & Molecular Biology

Study of DNA-emodin interaction by FTIR and UV-vis spectroscopy

Samuel T. Saito et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2012)

Article Hematology

Mechanism of Action: The Unique Pattern of Bendamustine-Induced Cytotoxicity

Lorenzo M. Leoni et al.

SEMINARS IN HEMATOLOGY (2011)

Article Pharmacology & Pharmacy

Bendamustine for the treatment of indolent non-Hodgkin's lymphoma and chronic lymphocytic leukemia

Anjana Elefante et al.

AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2010)

Article Biochemical Research Methods

Interaction Between Methylene Blue and CalfThymus Deoxyribonucleic Acid by Spectroscopic Technologies

Changlun Tong et al.

JOURNAL OF FLUORESCENCE (2010)

Article Spectroscopy

Interaction of an anthracycline disaccharide with ctDNA: Investigation by spectroscopic technique and modeling studies

Yan Lu et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2010)

Article Biochemistry & Molecular Biology

In situ electrochemical and AFM study of thalidomide-DNA interaction

S. C. B. Oliveira et al.

BIOELECTROCHEMISTRY (2009)

Article Spectroscopy

Solid state linear dichroic infrared spectral analysis of benzimidazoles and their N1-protonated salts

BB Ivanova

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2005)

Article Biochemistry & Molecular Biology

Thermodynamic characterization of the multivalent binding of chartreusin to DNA

F Barceló et al.

NUCLEIC ACIDS RESEARCH (2002)