相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The single-chain relaxin mimetic, B7-33, maintains the cardioprotective effects of relaxin and more rapidly reduces left ventricular fibrosis compared to perindopril in an experimental model of cardiomyopathy
Fariha Alam et al.
BIOMEDICINE & PHARMACOTHERAPY (2023)
A Lipidated Single-B-Chain Derivative of Relaxin Exhibits Improved In Vitro Serum Stability without Altering Activity
Praveen Praveen et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)
Challenges for Clinical Drug Development in Pulmonary Fibrosis
Eric S. White et al.
FRONTIERS IN PHARMACOLOGY (2022)
Characterization of a new potent and long-lasting single chain peptide agonist of RXFP1 in cells and in vivo translational models
Stephane Illiano et al.
SCIENTIFIC REPORTS (2022)
Synthetic short-chain peptide analogues of H1 relaxin lack affinity for the RXFP1 receptor and relaxin-like bioactivity. Clues to a better understanding of relaxin agonist design
Annunziata D'Ercole et al.
FRONTIERS IN PHARMACOLOGY (2022)
Identification of Potent and Long-Acting Single-Chain Peptide Mimetics of Human Relaxin-2 for Cardiovascular Diseases
Sergio Mallart et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Recombinant human H2 relaxin (serelaxin) as a cardiovascular drug: aiming at the right target
Daniele Bani
DRUG DISCOVERY TODAY (2020)
B7-33, a Functionally Selective Relaxin Receptor 1 Agonist, Attenuates Myocardial Infarction-Related Adverse Cardiac Remodeling in Mice
Teja Devarakonda et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2020)
Fibrosis: from mechanisms to medicines
Neil C. Henderson et al.
NATURE (2020)
Coatings Releasing the Relaxin Peptide Analogue B7-33 Reduce Fibrotic Encapsulation
Nicholas G. Welch et al.
ACS APPLIED MATERIALS & INTERFACES (2019)
Challenges in the design of insulin and relaxin/insulin-like peptide mimetics
Mohammed Akhter Hossain et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2018)
Relaxin as a Therapeutic Target for the Cardiovascular Complications of Diabetes
Hooi Hooi Ng et al.
FRONTIERS IN PHARMACOLOGY (2018)
Impact of heart failure and other comorbidities on mortality in patients with chronic obstructive pulmonary disease: a register-based, prospective cohort study
Elzbieta Kaszuba et al.
BMC FAMILY PRACTICE (2018)
Anti-fibrotic actions of relaxin
C. S. Samuel et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Vascular actions of relaxin: nitric oxide and beyond
C. H. Leo et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
B7-33 replicates the vasoprotective functions of human relaxin-2 (serelaxin)
Sarah A. Marshall et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2017)
Relaxin family peptides: structure-activity relationship studies
Nitin A. Patil et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Development of a Single-Chain Peptide Agonist of the Relaxin-3 Receptor Using Hydrocarbon Stapling
Keiko Hojo et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
SINGLE-CHAIN DERIVATIVE OF THE RELAXIN HORMONE IS A FUNCTIONALLY SELECTIVE AGONIST OF THE G PROTEIN-COUPLED RECEPTOR,RXFP1
M. A. Hossain et al.
JOURNAL OF PEPTIDE SCIENCE (2016)
A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1
Mohammed Akhter Hossain et al.
CHEMICAL SCIENCE (2016)
RELAXIN FAMILY PEPTIDES AND THEIR RECEPTORS
R. A. D. Bathgate et al.
PHYSIOLOGICAL REVIEWS (2013)
The Different Ligand-Binding Modes of Relaxin Family Peptide Receptors RXFP1 and RXFP2
Daniel J. Scott et al.
MOLECULAR ENDOCRINOLOGY (2012)
Dual Blockade of PKA and NF–κB Inhibits H2 Relaxin-Mediated Castrate-Resistant Growth of Prostate Cancer Sublines and Induces Apoptosis
Ruth L. Vinall et al.
Hormones & Cancer (2011)
Relaxin, a pleiotropic vasodilator for the treatment of heart failure
Sam L. Teichman et al.
HEART FAILURE REVIEWS (2009)
Solid phase synthesis and structural analysis of novel A-chain dicarba analogs of human relaxin-3 (INSL7) that exhibit full biological activity
Mohammed Akhter Hossain et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2009)
The pathophysiology of acute heart failure - Is it all about fluid accumulation?
Gad Cotter et al.
AMERICAN HEART JOURNAL (2008)
Acute heart failure as acute endothelitis - Interaction of fluid overload and endothelial dysfunction
Paolo C. Colombo et al.
EUROPEAN JOURNAL OF HEART FAILURE (2008)
Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules
Daniel J. Scott et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Using circular dichroism spectra to estimate protein secondary structure
Norma J. Greenfield
NATURE PROTOCOLS (2006)
Peptide helices based on alpha-amino acids
M Crisma et al.
BIOPOLYMERS (2006)
Cell signalling in the cardiovascular system: an overview
CPD Wheeler-Jones
HEART (2005)
Single turn peptide alpha helices with exceptional stability in water
NE Shepherd et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Activation of orphan receptors by the hormone relaxin
SY Hsu et al.
SCIENCE (2002)