Severe Spontaneous Hematomas in Patients Hospitalized with COVID-19

Review Hematology

COVID-19 Coagulopathy: From Pathogenesis to Treatment

Teba Alnima et al.

Summary: This review discusses the pathophysiology of the coagulation mechanism in COVID-19 patients and explores the interplay between the endothelium, immune system, and coagulation system. It also mentions vaccine-induced thrombotic thrombocytopenia and available anticoagulant treatment options.

ACTA HAEMATOLOGICA (2022)

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Article Cardiac & Cardiovascular Systems

Spontaneous Haematomas in Anticoagulated Covid-19 Patients: Diagnosis and Treatment by Embolization

Lorena Lopez-Martinez et al.

Summary: This study assessed the safety and efficacy of embolization for spontaneous bleeding in anticoagulated patients with COVID-19. The results showed that embolization successfully controlled the hematomas without complications and allowed patients to resume anticoagulation therapy. Follow-up visits demonstrated the good recovery of all treated patients.

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY (2022)

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Article Medicine, General & Internal

Rectus Sheath Hematoma in COVID-19 Patients as a Mortal Complication: A Retrospective Report

Hossein Zabihi Mahmoudabadi et al.

Summary: A multicentric study was conducted on 9 COVID-19 patients with rectus sheath hematoma. The study found that increased levels of inflammatory markers and a sudden decrease in blood hemoglobin may be predisposing factors for this complication. It was observed to be fatal in COVID-19 pneumonia patients.

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2022)

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Review Pharmacology & Pharmacy

Use of Anticoagulants in COVID-19: A Review

Sam Ngu et al.

Summary: COVID-19 is associated with increased risk of thrombotic events, and early studies have shown that disease severity and elevated D-dimer levels can predict thrombotic risk. However, there is limited data on postdischarge and outpatient patients. This review discusses the pathogenesis of COVID-related thrombosis and the evidence guiding thromboprophylaxis in inpatients, as well as emerging data from postdischarge and outpatient settings. The importance of risk stratification and individualized anticoagulation is emphasized.

AMERICAN JOURNAL OF THERAPEUTICS (2022)

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Article Radiology, Nuclear Medicine & Medical Imaging

Spontaneous Retroperitoneal Hematoma Treated with Percutaneous Transarterial Embolization in COVID-19 Era: Diagnostic Findings and Procedural Outcome

Francesco Tiralongo et al.

Summary: Spontaneous retroperitoneal hematomas are common in hospitalized patients with COVID-19 related pneumonia. Trans-arterial embolization (TAE) is a life-saving procedure after failure of medical and supportive therapy. This study evaluated the imaging features of spontaneous retroperitoneal hematomas and the safety, technical and clinical success of TAE in COVID-19 and non-COVID-19 patients. TAE was found to be a safe and effective option for the treatment of spontaneous retroperitoneal hematomas in COVID-19 patients.

TOMOGRAPHY (2022)

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Article Radiology, Nuclear Medicine & Medical Imaging

Abdominal Computed Tomography Angiography and Venography in Evaluation of Hemorrhagic and Thrombotic lesions in Hospitalized COVID-19 patients

Mohsen Ahmed Abdelmohsen et al.

Summary: This study found that both hemorrhagic and thromboembolic complications can occur in hospitalized patients with COVID-19, highlighting the importance of radiologists maintaining a high index of suspicion for early diagnosis of these complications.

CLINICAL IMAGING (2021)

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Article Cardiac & Cardiovascular Systems

Major bleeding complications in critically ill patients with COVID-19 pneumonia

Anne Godier et al.

Summary: In COVID-19 ICU patients, approximately 18% had major bleeding and 29% had thrombotic events. Bleeding occurred later than thrombosis, with coagulation disorders showing a biphasic evolution. Overdosing of anticoagulants was common in bleeding cases, suggesting the need for careful monitoring and adjustment of thromboprophylaxis.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2021)

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Article Cardiac & Cardiovascular Systems

Massive intraperitoneal hemorrhage in patients with COVID-19: a case series

Vahid Reisi-Vanani et al.

Summary: COVID-19 can lead to life-threatening complications such as intraperitoneal hemorrhage, highlighting the need for further research on the coagulopathy associated with the disease to guide treatment decisions.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2021)

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Letter Hematology

Rectus sheath and retroperitoneal haematomas in patients with Coronavirus 2019 infection

Phoebe Hazenberg et al.

BRITISH JOURNAL OF HAEMATOLOGY (2021)

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Article Medicine, General & Internal

Major Bleeding Complications in COVID-19 Patients

Ignacio Boira et al.

Summary: SARS-CoV-2 infection can lead to thrombotic or bleeding complications in patients, especially in those receiving therapeutic anticoagulation.

CUREUS JOURNAL OF MEDICAL SCIENCE (2021)

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Review Surgery