4.6 Article

Clinical outcomes of coronary intravascular lithotripsy in patients with stent failure (COIL registry)

期刊

INTERNATIONAL JOURNAL OF CARDIOLOGY
卷 391, 期 -, 页码 -

出版社

ELSEVIER IRELAND LTD
DOI: 10.1016/j.ijcard.2023.131274

关键词

Stent failure; Restenosis; Calcifications; Lithotripsy

向作者/读者索取更多资源

This study aimed to evaluate the safety, feasibility, and long-term outcomes of intravascular lithotripsy (IVL) in patients with stent failure. The results showed that IVL is a safe and feasible treatment for this high-risk group, with significant improvement in vessel diameter and degree of stenosis. However, the rate of major adverse cardiovascular events (MACE) within one year was relatively high.
Background: Intravascular lithotripsy (IVL) has been demonstrated to be an effective treatment of calcified de novo coronary lesions. Safety data on the use of IVL within stented segments are lacking. We sought to evaluate the safety, feasibility, and long-term outcomes of IVL in patients with stent failure.Methods: This was a retrospective multi-centre registry that included consecutive patients with stent failure who had undergone IVL treatment. The primary efficacy endpoint was procedural success defined as residual stenosis <30% (determined by quantitative coronary angiography analysis) in patients who survived hospital admission without in-hospital adverse events. Major adverse cardiovascular events (MACE) were defined as the composite endpoints of cardiovascular death, spontaneous myocardial infarction, and target vessel revascularisation at one-year follow up.Results: 102 patients were included in this study. Mean age was 73 +/- 9 years and 81% were male. The duration from previous stent implantation and IVL treatment was 24 (interquartile range 7-76) months, of which 10.8% received IVL for acute under-expanded stent. IVL treatment allowed significant improvement in both minimal lumen diameter (1.14 +/- 0.60 to 2.53 +/- 0.59, P < 0.001) and degree of stenosis (66.8 +/- 19.9 to 20.3 +/- 11.3%, P < 0.001). The rate of procedural success was 78.4% (80/102 of patients). The one-year MACE was 15.7%. Ostial disease (HR 5.16; 95% CI 1.19 to 22.33; P = 0.028) and lesion length (HR 1.05; 95% CI 1.01 to 1.10; P = 0.010) were independently associated with one-year MACE.Conclusions: In patients with stent failure, IVL is a safe and feasible treatment for this high-risk group.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据