Fever and dyspnea after anti-Covid-19 vaccination: a challenging diagnosis

There is still little information regarding the long-term safety of the vaccines. We report a case of new-onset adult-onset Still's disease (AOSD) that occurred following Covid-19 vaccination. This patient went to the emergency room with dyspnea from the last two weeks and bilateral swellings that occurred several weeks after the first vaccination. Based on the symptoms and laboratory results, we suspected AOSD. Considering the time relationship between Covid-19 vaccination and AOSD onset in our patient, and possible mechanisms linking vaccination with the onset of autoimmune disorders, physicians should consider adverse events from Covid-19 vaccination and assess the benefits and risks of vaccination for each patient.

Automated summary

A case of new-onset adult-onset Still's disease (AOSD) following Covid-19 vaccination is reported. The patient presented with dyspnea and bilateral swellings several weeks after the first vaccination, leading to suspicion of AOSD based on symptoms and laboratory results. Considering the timing between vaccination and autoimmune disorder onset, physicians should consider adverse events and assess the risks and benefits of Covid-19 vaccination for each patient.