Echocardiography phenotypes of right ventricular involvement in COVID-19 ARDS patients and ICU mortality: post-hoc (exploratory) analysis of repeated data from the ECHO-COVID study

Article Cardiac & Cardiovascular Systems

Prognostic value of right ventricular dilatation in patients with COVID-19: a multicentre study

Laurie Soulat-Dufour et al.

Summary: RV dilatation may be a key indicator of developing severe COVID-19 in patients. Male sex, higher body mass index, anticoagulation, and RV dilatation were independently associated with the primary composite outcome.

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING (2022)

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Letter Critical Care Medicine

Right ventricular failure is strongly associated with mortality in patients with moderate-to-severe COVID-19-related ARDS and appears related to respiratory worsening

Bruno Evrard et al.

INTENSIVE CARE MEDICINE (2022)

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Article Critical Care Medicine

Echocardiography findings in COVID-19 patients admitted to intensive care units: a multi-national observational study (the ECHO-COVID study)

Stephen Huang et al.

Summary: This study retrospectively describes the patterns of left and right ventricular dysfunction in severely ill COVID-19 patients following admission to the ICU. The results show that almost one-third of the patients had systolic dysfunction in either the left or right ventricle, with RV dysfunction being associated with positive pressure ventilation, hypercapnia, and pulmonary embolism. Age and the presence of acute cor pulmonale were also associated with mortality in this cohort.

INTENSIVE CARE MEDICINE (2022)

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Article Oncology

Multistate models for the natural history of cancer progression

Li C. Cheung et al.

Summary: In the settings we examined, we found that misspecifying a time-inhomogenous semi-Markov process as a time-homogeneous Markov process resulted in biased estimates of the mean sojourn times. When screen-detection of the intermediate disease leads to more frequent future screening assessments, there was minimal bias induced compared to when screen-detection of the intermediate disease leads to less frequent screening.

BRITISH JOURNAL OF CANCER (2022)

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Article Critical Care Medicine

Incidence of acute myocardial injury and its association with left and right ventricular systolic dysfunction in critically ill COVID-19 patients

Saga Jansson et al.

Summary: The study found a high incidence of acute myocardial injury (82%) in COVID-19 patients, while LV and RV dysfunction occurred in 28% and 22% of patients, respectively. Acute myocardial injury was associated with an increased need for mechanical ventilation and longer ICU stay, but not significantly associated with mortality.

ANNALS OF INTENSIVE CARE (2022)

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Article Critical Care Medicine

Right Ventricular Dysfunction in Early Sepsis and Septic Shock

Michael J. Lanspa et al.

Summary: This study found that right ventricular dysfunction is common in septic patients and is associated with over threefold higher 28-day mortality. LV systolic dysfunction, on the other hand, was not found to be significantly associated with increased mortality.

CHEST (2021)

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Article Cardiac & Cardiovascular Systems

Right ventricular dysfunction in critically ill COVID-19 ARDS

Caroline Bleakley et al.

Summary: Critically ill patients with severe COVID-19 ARDS exhibit a specific phenotype of RV radial impairment, highlighting the importance of not solely interpreting RV health based on long-axis parameters. RV-PA coupling may offer valuable additional insights into RV performance in this cohort.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2021)

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Review Anesthesiology

Right Ventricular Dysfunction in Patients With COVID-19: A Systematic Review and Meta-analysis

Gianluca Paternoster et al.

Summary: This study aimed to describe the features of right ventricular impairment and pulmonary hypertension in COVID-19 patients, and assess their impact on mortality. Findings showed that mortality rates were higher in COVID-19 patients requiring respiratory support and diagnosed with right ventricular dysfunction, dilatation, or pulmonary hypertension.

JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA (2021)

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Review Cardiac & Cardiovascular Systems

Mortality of right ventricular dysfunction in patients with acute respiratory distress syndrome subjected to lung protective ventilation: A systematic review and meta-analysis

Daoran Dong et al.

Summary: This study found that patients with ARDS and RVD or pulmonary vascular dysfunction have a higher mortality rate compared to ARDS patients without these conditions, with stable and reliable results.

HEART & LUNG (2021)

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Letter Critical Care Medicine

The difficulty in defining right ventricular failure at the bedside and its clinical significance

A. Vieillard-Baron et al.

ANNALS OF INTENSIVE CARE (2021)

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Review Critical Care Medicine

The impact of right ventricular injury on the mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis

Ryota Sato et al.

Summary: The presence of RV injury was significantly associated with increased overall and short-term mortality in patients with ARDS, as shown by a meta-analysis of 9 studies involving 1861 patients.

CRITICAL CARE (2021)

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Letter Cardiac & Cardiovascular Systems