Association between SARS-CoV-2 infections during pregnancy and preterm live birth

Article Immunology

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Testing and Detection During Peripartum Hospitalizations Among a Multicenter Cohort of Pregnant Persons: March 2020-February 2021

Miranda J. Delahoy et al.

Summary: This study analyzed electronic health record data from pregnant individuals at three healthcare networks in the US to investigate SARS-CoV-2 testing practices during peripartum hospitalizations. The findings revealed potential disparities in testing based on demographic and pregnancy characteristics, highlighting the need for equitable testing practices and care for pregnant individuals with SARS-CoV-2 infections.

CLINICAL INFECTIOUS DISEASES (2023)

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Review Obstetrics & Gynecology

Maternal infection with COVID-19 and increased risk of adverse pregnancy outcomes: a meta-analysis

Xin Wang et al.

Summary: This meta-analysis study demonstrates that COVID-19 infection increases the risks of premature birth, stillbirth, pre-eclampsia, and preterm premature rupture of membranes (PROM) during pregnancy. This highlights the importance of screening and early care for pregnant women with COVID-19.

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE (2022)

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Article Immunology

Incidence and Clinical Characteristics of and Risk Factors for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Among Pregnant Individuals in the United States

Fatimah S. Dawood et al.

Summary: This study followed a cohort of pregnant individuals from August 2020 to March 2021 and found that pregnant individuals had a 1% risk of SARS-CoV-2 infection per week during the circulation period of the virus, highlighting the importance of COVID-19 vaccination and other prevention measures during pregnancy while the virus is circulating in the community.

CLINICAL INFECTIOUS DISEASES (2022)

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Article Medicine, General & Internal

The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis

Shu Qin Wei et al.

Summary: Infection with COVID-19 during pregnancy may lead to an increased risk of preeclampsia, preterm birth, and other adverse pregnancy outcomes. Severe cases of COVID-19 are particularly associated with higher risks of complications such as preeclampsia, preterm birth, gestational diabetes, and low birth weight.

CANADIAN MEDICAL ASSOCIATION JOURNAL (2021)

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Article Immunology

Adverse Pregnancy Outcomes, Maternal Complications, and Severe Illness Among US Delivery Hospitalizations With and Without a Coronavirus Disease 2019 (COVID-19) Diagnosis

Jean Y. Ko et al.

Summary: This study explored the association between COVID-19 at delivery and adverse pregnancy outcomes, finding increased risks for several severe complications. Discharge status was not affected by COVID-19 diagnosis, and there were no significant differences in risk for complications or severe illness by race/ethnicity.

CLINICAL INFECTIOUS DISEASES (2021)

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Article Public, Environmental & Occupational Health

Risk for Stillbirth Among Women With and Without COVID-19 at Delivery Hospitalization — United States, March 2020–September 2021

Carla L. DeSisto et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

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Review Obstetrics & Gynecology

Placental histopathology after SARS-CoV-2 infection in pregnancy: a systematic review and meta-analysis

Raffaella Di Girolamo et al.

Summary: This study aimed to report the spectrum of placental pathology findings in pregnancies complicated by SARS-CoV-2 infection. A significant proportion of placentas in pregnant women with SARS-CoV-2 infection showed histopathologic findings suggestive of placental hypoperfusion and inflammation. Future multicenter prospective blinded studies are needed to correlate these placental lesions with pregnancy outcomes.

AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM (2021)

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Review Medicine, General & Internal

Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis

John Allotey et al.

BMJ-BRITISH MEDICAL JOURNAL (2020)

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Association between SARS-CoV-2 infections during pregnancy and preterm live birth

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