期刊
MICROBIOLOGICAL RESEARCH
卷 192, 期 -, 页码 203-210出版社
ELSEVIER GMBH
DOI: 10.1016/j.micres.2016.07.005
关键词
Microbial oil; Microbial genome; Trichosporon fermentans; Comparative analysis; Evolution
类别
资金
- National Natural Science Foundation of China [41271335, 31470191]
- Major State Basic Research Development Program of China (973 Program) [2015CB150502]
In this work, Trichosporon fermentans CICC 1368, which has been shown to accumulate cellular lipids efficiently using industry-agricultural wastes, was subjected to preliminary genome analysis, yielding a genome size of 31.3 million bases and 12,702 predicted protein-coding genes. Our analysis also showed a high degree of gene duplications and unique genes compared with those observed in other oleaginous yeasts, with 3-4-fold more genes related to fatty acid elongation and degradation compared with those in Rhodosporidium toruloides NP11 and Yarrowia lipolytica CLIB122. Phylogenetic analysis with other oleaginous microbes suggested that the lipogenic capacity of T. fermentans was obtained during evolution after the divergence of genera. Thus, our study provided the first draft genome and comparative analysis of T. fermentans, laying the foundation for its genetic improvement to facilitate cost-effective lipid production. (C) 2016 Elsevier GmbH. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据