4.3 Article

Ecliptasaponin A attenuates renal fibrosis by regulating the extracellular matrix of renal tubular cells

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Urology & Nephrology

Antifibrotic Agents for the Management of CKD: A Review

Marta Ruiz-Ortega et al.

Summary: Kidney fibrosis is a characteristic of chronic kidney disease and a potential target for therapy. However, there are challenges in directly targeting kidney fibrosis. It is unclear whether fibrosis causes or results from CKD progression, and there is a lack of tools to assess kidney fibrosis in clinical practice.

AMERICAN JOURNAL OF KIDNEY DISEASES (2022)

Article Integrative & Complementary Medicine

Pharmacological Mechanisms Underlying the Hepatoprotective Effects of Ecliptae herba on Hepatocellular Carcinoma

Botao Pan et al.

Summary: Through network pharmacology-based strategy and experimental verification, the potential mechanisms of Ecliptae herba against hepatocellular carcinoma (HCC) were systematically explored. It was found that Ecliptae herba may inhibit the proliferation of HCC cells and promote apoptosis through regulating pathways such as PI3K-AKT and HIF-1.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2021)

Article Chemistry, Medicinal

A natural product of acteoside ameliorate kidney injury in diabetes db/db mice and HK-2 cells via regulating NADPH/oxidase-TGF-β/Smad signaling pathway

Qinwen Wang et al.

Summary: The study found that acteoside exhibited renal protective effects by inhibiting specific signaling pathways in diabetes mice and high glucose-induced cells, regulating metabolic pathways. This research provides important insights for further exploring the pathogenesis and development of therapeutic agents for diabetic kidney disease.

PHYTOTHERAPY RESEARCH (2021)

Review Medicine, General & Internal

Matrix Metalloproteinases in Diabetic Kidney Disease

Nuria Garcia-Fernandez et al.

JOURNAL OF CLINICAL MEDICINE (2020)

Review Urology & Nephrology

Targeting the progression of chronic kidney disease

Marta Ruiz-Ortega et al.

NATURE REVIEWS NEPHROLOGY (2020)

Article Microbiology

Effects of Eclipta prostrata on gut microbiota of SAMp6 mice with osteoporosis

Xin Zhao et al.

JOURNAL OF MEDICAL MICROBIOLOGY (2019)

Review Biochemistry & Molecular Biology

Unilateral Ureteral Obstruction as a Model to Investigate Fibrosis-Attenuating Treatments

Elena Martinez-Klimova et al.

BIOMOLECULES (2019)

Article Integrative & Complementary Medicine

Hepatoprotective Effect of Wedelolactone against Concanavalin A-Induced Liver Injury in Mice

Qingqiong Luo et al.

AMERICAN JOURNAL OF CHINESE MEDICINE (2018)

Review Physiology

Mechanisms of Renal Fibrosis

Benjamin D. Humphreys

ANNUAL REVIEW OF PHYSIOLOGY, VOL 80 (2018)

Review Biochemistry & Molecular Biology

Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery

Nicholas Ekow Thomford et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Geriatrics & Gerontology

Effect of Eclipta prostrata on lipid metabolism in hyperlipidemic animals

Yun Zhao et al.

EXPERIMENTAL GERONTOLOGY (2015)

Article Food Science & Technology

Eclipta prostrata L. phytochemicals: Isolation, structure elucidation, and their antitumor activity

Qi-Mei Liu et al.

FOOD AND CHEMICAL TOXICOLOGY (2012)

Article Cell Biology

Overview of the Matrisome-An Inventory of Extracellular Matrix Constituents and Functions

Richard O. Hynes et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)

Article Cell Biology

Extracellular Matrix Degradation and Remodeling in Development and Disease

Pengfei Lu et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)

Review Urology & Nephrology

Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy

Robert L. Chevalier et al.

KIDNEY INTERNATIONAL (2009)

Review Cardiac & Cardiovascular Systems

Structure and function of matrix metalloproteinases and TIMPs

H Nagase et al.

CARDIOVASCULAR RESEARCH (2006)

Article Medicine, Research & Experimental

Disruption of the myocardial extracellular matrix leads to cardiac dysfunction

HE Kim et al.

JOURNAL OF CLINICAL INVESTIGATION (2000)