相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Prime editing for precise and highly versatile genome manipulation
Peter J. Chen et al.
NATURE REVIEWS GENETICS (2023)
Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy
Marcel P. Trefny et al.
NATURE COMMUNICATIONS (2023)
Diverse Approaches to Gene Therapy of Sickle Cell Disease
Shanna L. White et al.
ANNUAL REVIEW OF MEDICINE (2023)
High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails
Brian R. Shy et al.
NATURE BIOTECHNOLOGY (2023)
Structure of the human DICER-pre-miRNA complex in a dicing state
Young-Yoon Lee et al.
NATURE (2023)
Co-opting signalling molecules enables logic-gated control of CAR T cells
Aidan M. Tousley et al.
NATURE (2023)
Sequence determinant of small RNA production by DICER
Young-Yoon Lee et al.
NATURE (2023)
CAR immune cells: design principles, resistance and the next generation
Louai Labanieh et al.
NATURE (2023)
Determinants of resistance to engineered T cell therapies targeting CD19 in large B cell lymphomas
Brian J. Sworder et al.
CANCER CELL (2023)
CAR T therapy beyond cancer: the evolution of a living drug
Daniel J. Baker et al.
NATURE (2023)
In vivo hematopoietic stem cell modification by mRNA delivery
Laura Breda et al.
SCIENCE (2023)
CRISPR activation and interference screens decode stimulation responses in primary human T cells
Ralf Schmidt et al.
SCIENCE (2022)
CAR T cells produced in vivo to treat cardiac injury
Joel G. Rurik et al.
SCIENCE (2022)
Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells
Attya Omer-Javed et al.
CELL (2022)
CRISPR/Cas-based Human T cell Engineering: Basic Research and Clinical Application
Bettina E. Bernard et al.
IMMUNOLOGY LETTERS (2022)
Engineered cellular immunotherapies in cancer and beyond
Amanda V. Finck et al.
NATURE MEDICINE (2022)
Landscape of cancer cell therapies: trends and real-world data
Ana Rosa Saez-Ibanez et al.
NATURE REVIEWS DRUG DISCOVERY (2022)
MicroRNA-29a attenuates CD8 T cell exhaustion and induces memory-like CD8 T cells during chronic infection
Erietta Stelekati et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)
Emerging concepts of miRNA therapeutics: from cells to clinic
Caroline Diener et al.
TRENDS IN GENETICS (2022)
The landscape of mRNA nanomedicine
Xiangang Huang et al.
NATURE MEDICINE (2022)
Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma
Maartje W. Rohaan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2022)
Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence
Julia A. Belk et al.
CANCER CELL (2022)
Multidimensional control of therapeutic human cell function with synthetic gene circuits
Hui-Shan Li et al.
SCIENCE (2022)
Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies
Daniel B. Goodman et al.
Science Translational Medicine (2022)
speedingCARs: accelerating the engineering of CAR T cells by signaling domain shuffling and single-cell sequencing
Rocio Castellanos-Rueda et al.
NATURE COMMUNICATIONS (2022)
Selective miRNA inhibition in CD8+ cytotoxic T lymphocytes enhances HIV-1 specific cytotoxic responses
Nadia Madrid-Elena et al.
FRONTIERS IN IMMUNOLOGY (2022)
Forced expression of the non-coding RNA miR-17∼92 restores activation and function in CD28- deficient CD4+ T cells
Marianne Dolz et al.
ISCIENCE (2022)
CRISPR/CAS9 Gene Editing of MIR155HG in Primary Human T Cells to Prevent Acute Graft-Versus-Host Disease
Shrijan Khanal et al.
BLOOD (2022)
RASA2 ablation in T cells boosts antigen sensitivity and long-term function
Julia Carnevale et al.
NATURE (2022)
CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia
H. Frangoul et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
T cell circuits that sense antigen density with an ultrasensitive threshold
Rogelio A. Hernandez-Lopez et al.
SCIENCE (2021)
The Current Landscape of NKT Cell Immunotherapy and the Hills Ahead
Adam Nelson et al.
CANCERS (2021)
CAR T cells: Building on the CD19 paradigm
Anat Globerson-Levin et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2021)
Regulatory T Cell Therapy of Graft-versus-Host Disease: Advances and Challenges
Mehrdad Hefazi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis
Julian D. Gillmore et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering
Jennifer R. Hamilton et al.
CELL REPORTS (2021)
Role of miRNAs and lncRNAs in hematopoietic stem cell differentiation
Soudeh Ghafouri-Fard et al.
NON-CODING RNA RESEARCH (2021)
Virus-specific T-cell therapies for patients with primary immune deficiency
Michael D. Keller et al.
BLOOD (2020)
A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy
Greta Giordano-Attianese et al.
NATURE BIOTECHNOLOGY (2020)
CRISPR-engineered T cells in patients with refractory cancer
Edward A. Stadtmauer et al.
SCIENCE (2020)
miR-155 Overexpression in OT-1 CD8+ T Cells Improves Anti-Tumor Activity against Low-Affinity Tumor Antigen
Gwennaelle C. Monnot et al.
MOLECULAR THERAPY-ONCOLYTICS (2020)
Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies
Theodore L. Roth et al.
CELL (2020)
Gene modification strategies for next-generation CAR T cells against solid cancers
Yonggui Tian et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
De novo design of protein logic gates
Zibo Chen et al.
SCIENCE (2020)
Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors
Andrew V. Anzalone et al.
NATURE BIOTECHNOLOGY (2020)
A Fas-4-1BB fusion protein converts a death to a pro-survival signal and enhances T cell therapy
Shannon K. Oda et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
Precise T cell recognition programs designed by transcriptionally linking multiple receptors
Jasper Z. Williams et al.
SCIENCE (2020)
T-reg cell-based therapies: challenges and perspectives
Caroline Raffin et al.
NATURE REVIEWS IMMUNOLOGY (2020)
HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells
Harald Hartweger et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Modular and tunable biological feedback control using a de novo protein switch
Andrew H. Ng et al.
NATURE (2019)
De novo design of bioactive protein switches
Robert A. Langan et al.
NATURE (2019)
T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant
Aude G. Chapuis et al.
NATURE MEDICINE (2019)
miR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8+ T cell fate
Yun Ji et al.
NATURE COMMUNICATIONS (2019)
B cells engineered to express pathogen-specific antibodies protect against infection
Howell F. Moffett et al.
SCIENCE IMMUNOLOGY (2019)
Allogeneic hematopoietic cell transplantation; the current renaissance
Edward A. Copelan et al.
BLOOD REVIEWS (2019)
c-Jun overexpression in CAR T cells induces exhaustion resistance
Rachel C. Lynn et al.
NATURE (2019)
Reprogramming the antigen specificity of B cells using genome-editing technologies
James E. Voss et al.
ELIFE (2019)
MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice
Yongxia Wu et al.
BLOOD (2018)
Diverse functions of miR-17-92 cluster microRNAs in T helper cells
Dirk Baumjohann
CANCER LETTERS (2018)
MicroRNA-155 Modulates Acute Graft-versus-Host Disease by Impacting T Cell Expansion, Migration, and Effector Function
Nina C. Zitzer et al.
JOURNAL OF IMMUNOLOGY (2018)
Engineering Protein-Secreting Plasma Cells by Homology-Directed Repair in Primary Human B Cells
King L. Hung et al.
MOLECULAR THERAPY (2018)
IL-7 and CCL19 expression in CAR-T cells improves immune cell infiltration and CAR-T cell survival in the tumor
Keishi Adachi et al.
NATURE BIOTECHNOLOGY (2018)
In vivo generation of human CD19-CAR T cells results in B-cell depletion and signs of cytokine release syndrome
Anett Pfeiffer et al.
EMBO MOLECULAR MEDICINE (2018)
Reprogramming human T cell function and specificity with non-viral genome targeting
Theodore L. Roth et al.
NATURE (2018)
Emerging Cellular Therapies for Cancer
Sonia Guedan et al.
Annual Review of Immunology (2018)
Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
Eric Shifrut et al.
CELL (2018)
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
Justin Eyquem et al.
NATURE (2017)
In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers
Tyrel T. Smith et al.
NATURE NANOTECHNOLOGY (2017)
miR-150-Mediated Foxo1 Regulation Programs CD8+ T Cell Differentiation
Young Ho Ban et al.
CELL REPORTS (2017)
The Rise of Allogeneic Natural Killer Cells As a Platform for Cancer immunotherapy: Recent innovations and Future Developments
John P. Veluchamy et al.
FRONTIERS IN IMMUNOLOGY (2017)
A CD200R-CD28 fusion protein appropriates an inhibitory signal to enhance T-cell function and therapy of murine leukemia
Shannon K. Oda et al.
BLOOD (2017)
The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection
Howell F. Moffett et al.
NATURE IMMUNOLOGY (2017)
Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo
D. Sommermeyer et al.
LEUKEMIA (2016)
Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors
Kole T. Roybal et al.
CELL (2016)
MicroRNAs as regulatory elements in immune system logic
Arnav Mehta et al.
NATURE REVIEWS IMMUNOLOGY (2016)
MicroRNAs in Control of Stem Cells in Normal and Malignant Hematopoiesis
Christine Roden et al.
CURRENT STEM CELL REPORTS (2016)
Transgene-derived overexpression of miR-17-92 in CD8+ T-cells confers enhanced cytotoxic activity
Akemi Kosaka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice
Yongxia Wu et al.
BLOOD (2015)
A Single miRNA-mRNA Interaction Affects the Immune Response in a Context- and Cell-Type-Specific Manner
Li-Fan Lu et al.
IMMUNITY (2015)
Remote control of therapeutic T cells through a small molecule-gated chimeric receptor
Chia-Yung Wu et al.
SCIENCE (2015)
Type 1 diabetes immunotherapy using polyclonal regulatory T cells
Jeffrey A. Bluestone et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Predicting effective microRNA target sites in mammalian mRNAs
Vikram Agarwal et al.
ELIFE (2015)
miR-155 augments CD8+ T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic γc cytokines
Yun Ji et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
MicroRNAs in hematopoietic development
Sara Montagner et al.
BMC IMMUNOLOGY (2014)
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
F. Ann Ran et al.
CELL (2013)
MicroRNA-155 Is Required for Effector CD8+ T Cell Responses to Virus Infection and Cancer
Jan C. Dudda et al.
IMMUNITY (2013)
MicroRNA regulation of T-cell differentiation and function
Lukas T. Jeker et al.
IMMUNOLOGICAL REVIEWS (2013)
MicroRNA-directed program of cytotoxic CD8+ T-cell differentiation
Sara Trifari et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia
Renier J. Brentjens et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Expression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenografts
Masasuke Ohno et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2013)
MicroRNA-mediated regulation of T helper cell differentiation and plasticity
Dirk Baumjohann et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Regulation of acute graft-versus-host disease by microRNA-155
Parvathi Ranganathan et al.
BLOOD (2012)
The MicroRNA-17-92 Family of MicroRNA Clusters in Development and Disease
Carla P. Concepcion et al.
CANCER JOURNAL (2012)
miR-146a controls the resolution of T cell responses in mice
Lili Yang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC
Marc R. Fabian et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation
Shan Jiang et al.
BLOOD (2011)
Dicer recognizes the 5′ end of RNA for efficient and accurate processing
Jong-Eun Park et al.
NATURE (2011)
T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia
Michael Kalos et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
MicroRNA-155 Promotes Autoimmune Inflammation by Enhancing Inflammatory T Cell Development
Ryan M. O'Connell et al.
IMMUNITY (2010)
Abrogating Cbl-b in effector CD8+ T cells improves the efficacy of adoptive therapy of leukemia in mice
Ingunn M. Stromnes et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Hsc70/Hsp90 Chaperone Machinery Mediates ATP-Dependent RISC Loading of Small RNA Duplexes
Shintaro Iwasaki et al.
MOLECULAR CELL (2010)
Mammalian microRNAs predominantly act to decrease target mRNA levels
Huili Guo et al.
NATURE (2010)
miR-19 is a key oncogenic component of mir-17-92
Virginie Olive et al.
GENES & DEVELOPMENT (2009)
Targeted deletion reveals essential and overlapping functions of the miR-17∼92 family of miRNA clusters
Andrea Ventura et al.
CELL (2008)
Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes
Changchun Xiao et al.
NATURE IMMUNOLOGY (2008)
Requirement of bic/microRNA-155 for normal immune function
Antony Rodriguez et al.
SCIENCE (2007)
Regulation of the germinal center response by microRNA-155
To-Ha Thai et al.
SCIENCE (2007)
RNA polymerase III transcribes human microRNAs
Glen M. Borchert et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
Cancer regression in patients after transfer of genetically engineered lymphocytes
Richard A. Morgan et al.
SCIENCE (2006)
miRBase: microRNA sequences, targets and gene nomenclature
Sam Griffiths-Jones et al.
NUCLEIC ACIDS RESEARCH (2006)
A microRNA polycistron as a potential human oncogene
L He et al.
NATURE (2005)
MicroRNA genes are transcribed by RNA polymerase II
Y Lee et al.
EMBO JOURNAL (2004)
A uniform system for microRNA annotation
V Ambros et al.
RNA (2003)
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
ME Dudley et al.
SCIENCE (2002)
Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
L Ruggeri et al.
SCIENCE (2002)
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
G Hutvágner et al.
SCIENCE (2001)
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C-elegans developmental timing
A Grishok et al.
CELL (2001)