A SERS active bimetallic core-satellite nanostructure for the ultrasensitive detection of Mucin-1

In this study, we established gold nanorods (Au NRs) core-silver nanoparticles (Ag NPs) satellite assemblies as an ultrasensitive aptamer-based SERS sensor for the detection of Mucin-1, a specific breast cancer marker protein. The limit of detection (LOD) was 4.3 aM and the wide linear range was 0.005-1 fM.