期刊
METHODS
卷 107, 期 -, 页码 42-47出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ymeth.2016.05.011
关键词
RNA editing; Post-transcriptional gene regulation; RNA sequencing
资金
- Stanford Graduate Fellowship
- NIH [R01GM102484]
- Ellison Medical Foundation
A-to-I RNA editing is an essential gene regulatory mechanism. Once thought to be a rare phenomenon only occurring in a few transcripts, the emergence of high-throughput RNA sequencing has facilitated the identification of over 2 million RNA editing sites in the human transcriptome. In this review, we survey the current RNA-seq based methods as well as historical methods used to identify RNA editing sites. (C) 2016 Elsevier Inc. All rights reserved.
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