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Implications of maternal-fetal health on perinatal stem cell banking

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GENE THERAPY
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SPRINGERNATURE
DOI: 10.1038/s41434-023-00426-w

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This review discusses the therapeutic potential of gestational tissues and their derived stem cells, and explores the impact of birth trends, delivery methods, and pregnancy complications on perinatal stem cell banking.
Cell based therapies are being assessed for their therapeutic potential across a variety of diseases. Gestational tissues are attractive sources for cell therapy. The large number of births worldwide ensures sufficient access to gestational tissues, however, limited information has been reported around the impact of birth trends, delivery methods and pregnancy conditions on perinatal stem cell banking. This review describes the current state of banking of gestational tissues and their derived perinatal stem cells, discusses why the changes in birth trends and delivery methods could affect gestational tissue banking practices, and further explores how common pregnancy complications can potentially influence perinatal stem cell banking.

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