相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。2022 FDA approvals
Asher Mullard
NATURE REVIEWS DRUG DISCOVERY (2023)
Metastatic Prostate Cancer-A Review of Current Treatment Options and Promising New Approaches
Philip Posdzich et al.
CANCERS (2023)
The positive relationship between androgen receptor splice variant-7 expression and the risk of castration-resistant prostate cancer: A cumulative analysis
Shankun Zhao et al.
FRONTIERS IN ONCOLOGY (2023)
Strong immune responses and protection of PcrV and OprF-I mRNA vaccine candidates against Pseudomonas aeruginosa
Xingyun Wang et al.
NPJ VACCINES (2023)
Clinical Pharmacology of RNA Interference-Based Therapeutics: A Summary Based on Food and Drug Administration-Approved Small Interfering RNAs
Xing Jing et al.
DRUG METABOLISM AND DISPOSITION (2023)
DKK1-targeting cholesterol-modified siRNA implication in hair growth regulation
Dimitri Papukashvili et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2023)
Where should siRNAs go: applicable organs for siRNA drugs
Insook Ahn et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2023)
Loading of cocktail siRNAs into extracellular vesicles via TAT-DRBD peptide for the treatment of castration-resistant prostate cancer
Yanjun Diao et al.
CANCER BIOLOGY & THERAPY (2022)
Preferential siRNA delivery to injured kidneys for combination treatment of acute kidney injury
Weimin Tang et al.
JOURNAL OF CONTROLLED RELEASE (2022)
2021 FDA approvals
Asher Mullard
NATURE REVIEWS DRUG DISCOVERY (2022)
Identification of Tumor Antigens and Design of mRNA Vaccine for Colorectal Cancer Based on the Immune Subtype
Cong Liu et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2022)
Prostate Cancer Incidence and Mortality: Global Status and Temporal Trends in 89 Countries From 2000 to 2019
Le Wang et al.
FRONTIERS IN PUBLIC HEALTH (2022)
Re: The Genetic Source Tracking of Human Urinary Exosomes
Anthony Atala
JOURNAL OF UROLOGY (2022)
Anti-Androgen Receptor Therapies in Prostate Cancer: A Brief Update and Perspective
Jian Huang et al.
FRONTIERS IN ONCOLOGY (2022)
Development of an LNP-Encapsulated mRNA-RBD Vaccine against SARS-CoV-2 and Its Variants
Cong Liu et al.
PHARMACEUTICS (2022)
Development and Evaluation of a PSMA-Targeted Nanosystem Co-Packaging Docetaxel and Androgen Receptor siRNA for Castration-Resistant Prostate Cancer Treatment
Yingying Zhang et al.
PHARMACEUTICS (2022)
Definition of Castrate Resistant Prostate Cancer: New Insights
Juan Morote et al.
BIOMEDICINES (2022)
Blood-based liquid biopsies for prostate cancer: clinical opportunities and challenges
Blanca Trujillo et al.
BRITISH JOURNAL OF CANCER (2022)
Potential utility of miRNAs for liquid biopsy in breast cancer
Xiangrong Liu et al.
FRONTIERS IN ONCOLOGY (2022)
Emerging Proteins in CRPC: Functional Roles and Clinical Implications
Piaoping Kong et al.
FRONTIERS IN ONCOLOGY (2022)
Self-Amplifying RNA Approach for Protein Replacement Therapy
Dimitri Papukashvili et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
The Crucial Role of AR-V7 in Enzalutamide-Resistance of Castration-Resistant Prostate Cancer
Zeyuan Zheng et al.
CANCERS (2022)
Peptide-siRNA nanoparticles targeting NF-KB p50 mitigate experimental abdominal aortic aneurysm progression and rupture
Huimin Yan et al.
BIOMATERIALS ADVANCES (2022)
Targeting signaling pathways in prostate cancer: mechanisms and clinical trials
Yundong He et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2022)
The growth of siRNA-based therapeutics: Updated clinical studies
M. May Zhang et al.
BIOCHEMICAL PHARMACOLOGY (2021)
Lumasiran: First Approval
Lesley J. Scott et al.
DRUGS (2021)
2020 FDA drug approvals
Asher Mullard
NATURE REVIEWS DRUG DISCOVERY (2021)
Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancer
Masahiro Sugiura et al.
TRANSLATIONAL ONCOLOGY (2021)
Mesoporous silica nanoparticles combined with AKR1C3 siRNA inhibited the growth of castration-resistant prostate cancer by suppressing androgen synthesis in vitro and in vivo
Junyu Chen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)
Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Hyuna Sung et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2021)
Prostate cancer castrate resistant progression usage of non-canonical androgen receptor signaling and ketone body fuel
Estefania Labanca et al.
ONCOGENE (2021)
Advances in siRNA delivery strategies for the treatment of MDR cancer
Md Abdus Subhan et al.
LIFE SCIENCES (2021)
YAP1 overexpression contributes to the development of enzalutamide resistance by induction of cancer stemness and lipid metabolism in prostate cancer
Hsiu-Chi Lee et al.
ONCOGENE (2021)
Development of EphA2 siRNA-loaded lipid nanoparticles and combination with a small-molecule histone demethylase inhibitor in prostate cancer cells and tumor spheroids
Ezgi Oner et al.
JOURNAL OF NANOBIOTECHNOLOGY (2021)
Seed-mediated RNA interference of androgen signaling and survival networks induces cell death in prostate cancer cells
Joshua M. Corbin et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2021)
Perspectives on miRNAs Targeting DKK1 for Developing Hair Regeneration Therapy
Dimitri Papukashvili et al.
CELLS (2021)
Impact and effectiveness of mRNA BNT162b2 vaccine against SARS-CoV-2 infections and COVID-19 cases, hospitalisations, and deaths following a nationwide vaccination campaign in Israel: an observational study using national surveillance data
Eric J. Haas et al.
LANCET (2021)
Treatment and trials in non-metastatic castration-resistant prostate cancer
Soum D. Lokeshwar et al.
NATURE REVIEWS UROLOGY (2021)
Improved cardiac-specific delivery of RAGE siRNA within small extracellular vesicles engineered to express intense cardiac targeting peptide attenuates myocarditis
Hyoeun Kim et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2021)
Synthesis of KUE-siRNA Conjugates for Prostate Cancer Cell-Targeted Gene Silencing
Chao Yang et al.
CHEMBIOCHEM (2021)
siRNA: Mechanism of action, challenges, and therapeutic approaches
Walhan Alshaer et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2021)
AR-V7 in Metastatic Prostate Cancer: A Strategy beyond Redemption
Navid Sobhani et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
Namit Chaudhary et al.
NATURE REVIEWS DRUG DISCOVERY (2021)
Clinicopathological characteristics of androgen receptor splicing variant 7 (AR-V7) expression in patients with castration resistant prostate cancer: A systematic review and meta-analysis
Qinchen Li et al.
TRANSLATIONAL ONCOLOGY (2021)
Suppression of FGF5 and FGF18 Expression by Cholesterol-Modified siRNAs Promotes Hair Growth in Mice
Jungang Zhao et al.
FRONTIERS IN PHARMACOLOGY (2021)
AR Splicing Variants and Resistance to AR Targeting Agents
Mayuko Kanayama et al.
CANCERS (2021)
Molecular Phenotyping of AR Signaling for Predicting Targeted Therapy in Castration Resistant Prostate Cancer
Agus Rizal A. H. Hamid et al.
FRONTIERS IN ONCOLOGY (2021)
Clinical Advances of siRNA-Based Nanotherapeutics for Cancer Treatment
Dima Hattab et al.
PHARMACEUTICS (2021)
The Emerging Mechanisms of Wnt Secretion and Signaling in Development
Shefali Mehta et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Recent Global Patterns in Prostate Cancer Incidence and Mortality Rates
MaryBeth B. Culp et al.
EUROPEAN UROLOGY (2020)
The role of actinin-4 (ACTN4) in exosomes as a potential novel therapeutic target in castration-resistant prostate cancer
Yu Ishizuya et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)
Baldness and Risk of Prostate Cancer in the Health Professionals Follow-up Study
Saud Khan et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2020)
2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer
Arnaud Blomme et al.
NATURE COMMUNICATIONS (2020)
Analysis of AR-FL and AR-V1 in Whole Blood of Patients with Castration Resistant Prostate Cancer as a Tool for Predicting Response to Abiraterone Acetate
Kristina Stuopelyte et al.
JOURNAL OF UROLOGY (2020)
Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol
Kausik K. Ray et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Generation and validation of structurally defined antibody-siRNA conjugates
Alex R. Nanna et al.
NUCLEIC ACIDS RESEARCH (2020)
Aspartate β-hydroxylase targeting in castration-resistant prostate cancer modulates the NOTCH/HIF1α/GSK3β crosstalk
Paola Barboro et al.
CARCINOGENESIS (2020)
The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling
Boris Y. Shorning et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Efficacy and Safety of Androgen-Deprivation Therapy Combined with Docetaxel Plus Prednisone in High-Burden Metastatic Hormone-Sensitive Prostate Cancer
Linjun Hu et al.
CANCER MANAGEMENT AND RESEARCH (2020)
Protein Expression Analysis of an In Vitro Murine Model of Prostate Cancer Progression: Towards Identification of High-Potential Therapeutic Targets
Hisham F. Bahmad et al.
JOURNAL OF PERSONALIZED MEDICINE (2020)
Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates
Kizzmekia S. Corbett et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates
Edward E. Walsh et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Targeting the Wnt/β-catenin signaling pathway in cancer
Ya Zhang et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
α-Actinin-4 Promotes the Progression of Prostate Cancer Through the Akt/GSK-3β/β-Catenin Signaling Pathway
Sungyeon Park et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Development and prevalence of castration-resistant prostate cancer subtypes
Jordan E. Vellky et al.
NEOPLASIA (2020)
Progress in Delivery of siRNA-Based Therapeutics Employing Nano-Vehicles for Treatment of Prostate Cancer
Milad Ashrafizadeh et al.
BIOENGINEERING-BASEL (2020)
Hypofractionated Radiation Therapy for Localized Prostate Cancer: Executive Summary of an ASTRO, ASCO and AUA Evidence-Based Guideline
Scott C. Morgan et al.
JOURNAL OF UROLOGY (2019)
Comparative Analysis of AR Variant AR-V567es mRNA Detection Systems Reveals Eminent Variability and Questions the Role as a Clinical Biomarker in Prostate Cancer
Christof Bernemann et al.
CLINICAL CANCER RESEARCH (2019)
Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach
Ghanbar Mahmoodi Chalbatani et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)
Codelivery of GRP78 siRNA and docetaxel via RGD-PEG-DSPE/DOPA/CaP nanoparticles for the treatment of castration-resistant prostate cancer
Xiangyu Zhang et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2019)
Selective targeting of PARP-2 inhibits androgen receptor signaling and prostate cancer growth through disruption of FOXA1 function
Bin Gui et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
p66Shc protein through a redox mechanism enhances the progression of prostate cancer cells towards castration-resistance
Dannah R. Miller et al.
FREE RADICAL BIOLOGY AND MEDICINE (2019)
Role of Androgen Receptor in Prostate Cancer: A Review
Kazutoshi Fujita et al.
WORLD JOURNAL OF MENS HEALTH (2019)
Proteogenomic Characterization of Patient-Derived Xenografts Highlights the Role of REST in Neuroendocrine Differentiation of Castration-Resistant Prostate Cancer
Amilcar Flores-Morales et al.
CLINICAL CANCER RESEARCH (2019)
Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer
Adam Sharp et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
Suppression of prostate tumor cell survival by antisense oligonucleotide-mediated inhibition of AR-V7 mRNA synthesis
Maria V. Luna Velez et al.
ONCOGENE (2019)
Patisiran, an RNAi therapeutic for the treatment of hereditary transthyretin-mediated amyloidosis
Arnt Kristen et al.
NEURODEGENERATIVE DISEASE MANAGEMENT (2019)
The Current Landscape of Treatment in Non-Metastatic Castration-Resistant Prostate Cancer
Joelle El-Amm et al.
CLINICAL MEDICINE INSIGHTS-ONCOLOGY (2019)
Prostate cancer proteomics: clinically useful protein biomarkers and future perspectives
Paula Intasqui et al.
EXPERT REVIEW OF PROTEOMICS (2018)
Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia
A. Premanand et al.
ARCHIVES OF DERMATOLOGICAL RESEARCH (2018)
Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases
Heini M. L. Kallio et al.
BRITISH JOURNAL OF CANCER (2018)
p66Shc regulates migration of castration-resistant prostate cancer cells
Matthew A. Ingersoll et al.
CELLULAR SIGNALLING (2018)
SEMA3C drives cancer growth by transactivating multiple receptor tyrosine kinases via Plexin B1
James W. Peacock et al.
EMBO MOLECULAR MEDICINE (2018)
Male pattern baldness and incidence of prostate cancer A systematic review and meta-analysis
Huadong He et al.
MEDICINE (2018)
Overexpression of α (1,6) fucosyltransferase in the development of castration-resistant prostate cancer cells
Naseruddin Hoti et al.
PROSTATE CANCER AND PROSTATIC DISEASES (2018)
Inflammation and NF-κB Signaling in Prostate Cancer: Mechanisms and Clinical Implications
Jens Staal et al.
CELLS (2018)
Targeting Semaphorin 3C in Prostate Cancer With Small Molecules
Chung C. W. Lee et al.
JOURNAL OF THE ENDOCRINE SOCIETY (2018)
Androgen receptor-dependent and -independent mechanisms driving prostate cancer progression: Opportunities for therapeutic targeting from multiple angles
David T. Hoang et al.
ONCOTARGET (2017)
Dissecting major signaling pathways in prostate cancer development and progression: Mechanisms and novel therapeutic targets
Senthilmurugan Ramalingam et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2017)
WNT signalling in prostate cancer
Virginia Murillo-Garzon et al.
NATURE REVIEWS UROLOGY (2017)
Proteomics analyses of prostate cancer cells reveal cellular pathways associated with androgen resistance
Naseruddin Hoeti et al.
PROTEOMICS (2017)
Vinculin and filamin-C are two potential prognostic biomarkers and therapeutic targets for prostate cancer cell migration
Jianzhong Ai et al.
ONCOTARGET (2017)
Androgen receptor amplification is concordant between circulating tumor cells and biopsies from men undergoing treatment for metastatic castration resistant prostate cancer
Jennifer Podolak et al.
ONCOTARGET (2017)
Androgen receptor splice variants and prostate cancer: From bench to bedside
Kristine M. Wadosky et al.
Oncotarget (2017)
Adaptive phenotype drives resistance to androgen deprivation therapy in prostate cancer
Nicoletta Ferrari et al.
CELL COMMUNICATION AND SIGNALING (2017)
Androgen Receptor Variant AR-V9 Is Coexpressed with AR-V7 in Prostate Cancer Metastases and Predicts Abiraterone Resistance
Manish Kohli et al.
CLINICAL CANCER RESEARCH (2017)
Comparative Proteomics Uncovers Correlated Signaling Network and Potential Biomarkers for Progression of Prostate Cancer
Jianzhong Ai et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)
Enzalutamide: targeting the androgen signalling pathway in metastatic castration-resistant prostate cancer
Jack Schalken et al.
BJU INTERNATIONAL (2016)
Androgen receptor signaling in castration-resistant prostate cancer: a lesson in persistence
Isabel Coutinho et al.
ENDOCRINE-RELATED CANCER (2016)
Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Prostate Cancer
Jonathan Welti et al.
EUROPEAN UROLOGY (2016)
The Proteome of Primary Prostate Cancer
Diego Iglesias-Gato et al.
EUROPEAN UROLOGY (2016)
A Whole Blood Assay for AR-V7 and ARv567es in Patients with Prostate Cancer
Xichun Liu et al.
JOURNAL OF UROLOGY (2016)
Silencing Myostatin Using Cholesterol-conjugated siRNAs Induces Muscle Growth
Tayeba Khan et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2016)
Androgen Receptor Splice Variants Dimerize to Transactivate Target Genes
Duo Xu et al.
CANCER RESEARCH (2015)
siRNA Lipid Nanoparticle Potently Silences Clusterin and Delays ProgressionWhen Combined with Androgen Receptor Cotargeting in Enzalutamide-Resistant Prostate Cancer
Yoshiaki Yamamoto et al.
CLINICAL CANCER RESEARCH (2015)
Androgen Receptor Gene Aberrations in Circulating Cell-Free DNA: Biomarkers of Therapeutic Resistance in Castration-Resistant Prostate Cancer
Arun A. Azad et al.
CLINICAL CANCER RESEARCH (2015)
Persistent androgen receptor addiction in castration-resistant prostate cancer
Michael T. Schweizer et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2015)
Elevated Circulating Tissue Inhibitor of Metalloproteinase 1 (TIMP-1) Levels Are Associated With Neuroendocrine Differentiation in Castration Resistant Prostate Cancer
Yixuan Gong et al.
PROSTATE (2015)
siRNA Versus miRNA as Therapeutics for Gene Silencing
Jenny K. W. Lam et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2015)
Androgen receptor: structure, role in prostate cancer and drug discovery
M. H. Eileen Tan et al.
ACTA PHARMACOLOGICA SINICA (2015)
In vivo quantitative phosphoproteomic profiling identifies novel regulators of castration-resistant prostate cancer growth
N. Jiang et al.
ONCOGENE (2015)
Inhibition of NF-kappa B signaling restores responsiveness of castrate-resistant prostate cancer cells to anti-androgen treatment by decreasing androgen receptor-variant expression
R. Jin et al.
ONCOGENE (2015)
Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer
Philip A. Watson et al.
NATURE REVIEWS CANCER (2015)
Overexpression of α (1,6) fucosyltransferase associated with aggressive prostate cancer
Xiangchun Wang et al.
GLYCOBIOLOGY (2014)
Elevated levels of FOXA1 facilitate androgen receptor chromatin binding resulting in a CRPC-like phenotype
J. L. L. Robinson et al.
ONCOGENE (2014)
Androgen Receptor (AR) Physiological Roles in Male and Female Reproductive Systems: Lessons Learned from AR-Knockout Mice Lacking AR in Selective Cells
Chawnshang Chang et al.
BIOLOGY OF REPRODUCTION (2013)
Age-Dependent Associations between Androgenetic Alopecia and Prostate Cancer Risk
David C. Muller et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2013)
Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2-induced STAT3 activation
Kouji Izumi et al.
EMBO MOLECULAR MEDICINE (2013)
Epithelial cell adhesion molecule (EpCAM) is associated with prostate cancer metastasis and chemo/radioresistance via the PI3K/Akt/mTOR signaling pathway
Jie Ni et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)
Quantitative Proteomics Reveals That Enzymes of the Ketogenic Pathway Are Associated with Prostate Cancer Progression
Punit Saraon et al.
MOLECULAR & CELLULAR PROTEOMICS (2013)
Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo
Justin B. Lee et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Prostate-targeted biodegradable nanoparticles loaded with androgen receptor silencing constructs eradicate xenograft tumors in mice
Jun Yang et al.
NANOMEDICINE (2012)
The mutational landscape of lethal castration-resistant prostate cancer
Catherine S. Grasso et al.
NATURE (2012)
Wnt/β-catenin signalling in prostate cancer
Robert M. Kypta et al.
NATURE REVIEWS UROLOGY (2012)
Male pattern baldness and the risk of prostate cancer
M. Yassa et al.
ANNALS OF ONCOLOGY (2011)
Serum testosterone is associated with aggressive prostate cancer in older men: results from the Baltimore Longitudinal Study of Aging
Phillip M. Pierorazio et al.
BJU INTERNATIONAL (2010)
Male pattern baldness and prostate cancer risk in a population-based case-control study
Jonathan L. Wright et al.
CANCER EPIDEMIOLOGY (2010)
Detection of Androgen Receptor Mutations in Circulating Tumor Cells in Castration-Resistant Prostate Cancer
Yuqiu Jiang et al.
CLINICAL CHEMISTRY (2010)
Adeno-associated virus-delivered short hairpin-structured RNA for androgen receptor gene silencing induces tumor eradication of prostate cancer xenografts in nude mice: a preclinical study
Aijing Sun et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
Regulation of Androgen Receptor Transcriptional Activity and Specificity by RNF6-induced Ubiquitination
Kexin Xu et al.
CANCER CELL (2009)
Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer
Rong Hu et al.
CANCER RESEARCH (2009)
In vivo Knockdown of the Androgen Receptor Results in Growth Inhibition and Regression of Well-Established, Castration-Resistant Prostate Tumors
Robert Snoek et al.
CLINICAL CANCER RESEARCH (2009)
Src Family Kinase Activity Is Up-Regulated in Hormone-Refractory Prostate Cancer
Oleg Tatarov et al.
CLINICAL CANCER RESEARCH (2009)
Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: Recommendations of the prostate cancer clinical trials working group
Howard I. Scher et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Dihydrotestosterone-inducible dickkopf 1 from balding dermal papilla cells causes apoptosis in follicular keratinocytes
Mi Hee Kwack et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2008)
OligoWalk: an online siRNA design tool utilizing hybridization thermodynamics
Zhi John Lu et al.
NUCLEIC ACIDS RESEARCH (2008)
SIRNA-Directed In Vivo Silencing of Androgen Receptor Inhibits the Growth of Castration-Resistant Prostate Carcinomas
Daniel Compagno et al.
PLOS ONE (2007)
β-Catenin destruction complex:: insights and questions from a structural perspective
D. Kimelman et al.
ONCOGENE (2006)
Short hairpin RNA knockdown of the androgen receptor attenuates ligand-independent activation and delays tumor progression
Helen Cheng et al.
CANCER RESEARCH (2006)
Activation of nuclear factor-κB in human prostate carcinogenesis and association to biochemical relapse
J Domingo-Domenech et al.
BRITISH JOURNAL OF CANCER (2005)
Serum testosterone and the risk of prostate cancer: Potential implications for testosterone therapy
JK Parsons et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2005)
Androgen receptor down regulation by small interference RNA induces cell growth inhibition in androgen sensitive as well as in androgen independent prostate cancer cells
P Hååg et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2005)
Small-interfering RNA-induced androgen receptor silencing leads to apoptotic cell death in prostate cancer
XB Liao et al.
MOLECULAR CANCER THERAPEUTICS (2005)
β-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation
DL Daniels et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
High levels of circulating testosterone are not associated with increased prostate cancer risk: A pooled prospective study
P Stattin et al.
INTERNATIONAL JOURNAL OF CANCER (2004)
Pretreatment total testosterone level predicts pathological stage in patients with localized prostate cancer treated with radical prostatectomy
JC Massengill et al.
JOURNAL OF UROLOGY (2003)
Molecular biology of the androgen receptor: From molecular understanding to the clinic
IE Eder et al.
EUROPEAN UROLOGY (2001)
Cytokine variations in patients with hormone treated prostate cancer
GJ Wise et al.
JOURNAL OF UROLOGY (2000)