期刊
CHEMICAL COMMUNICATIONS
卷 51, 期 28, 页码 6161-6163出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc00356c
关键词
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Acid ceramidase is responsible for the ultimate step in the catabolism of (glyco)sphingolipids by hydrolysis of ceramide into sphingosine and free fatty acid. Deficiency in acid ceramidase is the molecular basis of Farber disease. Here we report the synthesis and characterization of an activity-based acid ceramidase probe.
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