4.7 Article

Electrochemically triggered release of human insulin from an insulin-impregnated reduced graphene oxide modified electrode

期刊

CHEMICAL COMMUNICATIONS
卷 51, 期 75, 页码 14167-14170

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc05539c

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资金

  1. Centre National de la Recherche Scientifique (CNRS)
  2. University Lille 1
  3. Nord-Pas-de Calais region
  4. Institut Universitaire de France (IUF)
  5. Project PHC Hubert MAIMONIDE [31774TD]
  6. European Genomic Institute for Diabetes'' (E.G.I.D.) [ANR-10-LABX-46]
  7. European Commission
  8. Ministry of Science, Technology and Space, Israel in the cooperation with France

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An electrochemical insulin-delivery system based on reduced graphene oxide impregnated with insulin is described. Upon application of a potential pulse of -0.8 V for 30 min, up to 70 +/- 4% of human insulin was released into a physiological medium while preserving its biological activity.

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