期刊
FITOTERAPIA
卷 170, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.fitote.2023.105657
关键词
Rumex dentatus; Polygonaceae; Antifungal activity; Naphthalenes
Four new phenolic compounds were isolated from the roots of Rumex dentatus L., including two naphthalenes, one chromone, and one xanthone. Compound 1 showed moderate antifungal activity against Epidermophyton floccosum.
Four new phenolic compounds, including two naphthalenes, musizin-8-O-& beta;-D-(6 & PRIME;-O-malonyl-3 & PRIME;& PRIME;-methoxy)glucopyranoside (1) and 2-acetyl-3-methyl-1,4-naphtho-quinone-8-O-& beta;-D-glucopyranoside (2), one chromone, (2 & PRIME;R)-7hydroxy-2-(2 & PRIME;-hydroxypropyl)-5-methyl acetate chromone (3), and one xanthone, 2,8-dimethyl-3,6-dihydroxyxanthone (4) were isolated from the roots of Rumex dentatus L. (Polygonaceae). In addition, five known including four naphthalenes (5-8) and one chromone (9) were also obtained. Their structures were determined by means of extensive spectroscopic analysis and acidic hydrolysis. Compound 1 showed moderate antifungal activity against Epidermophyton floccosum, with inhibitory rate of 39.539 & PLUSMN; 0.412% at a concentration of 100 & mu;M.
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