Achyrocline satureioides review: From the pharmacochemical diversity to the technological development of products

Achyrocline satureioides (Lam.) DC (Asteraceae) is a native species of the southeastern subtropical and temperate region of South America, popularly known as marcela or macela. This species is recognized, in traditional medicine, by diverse biological activities such as digestive, antispasmodic, anti-inflammatory, antiviral, sedative, hepatoprotective, among others. Some of these activities have been related to the presence of phenolic com-pounds, including flavonoids, phenolic acids, terpenoids in the essential oils, coumarins and phloroglucinol derivatives reported to the species. The approaches on the technological development of phytopharmaceutical products of this species provided relevant advances in the optimization of the extraction and product obtention, especially spray-dried powders, hydrogels, ointments, granules, films, nanoemulsions and nanocapsules. The most relevant biological activities described for the extracts or derivative products from A. satureioides were antioxidant, neuroprotective, antidiabetic, antiobesity, antimicrobial, anticancer effects, and obstructive sleep apnea syndrome. The scientific and technological findings reported for the species, in conjunction with its traditional use and cultivation, reveal the high potential of the species for diverse industrial applications.

Automated summary

Achyrocline satureioides, also known as marcela or macela, is a native species of the southeastern subtropical and temperate region of South America. It has been recognized in traditional medicine for its various biological activities such as digestive, antispasmodic, anti-inflammatory, antiviral, sedative, and hepatoprotective effects. The presence of phenolic compounds, including flavonoids, phenolic acids, and terpenoids, contribute to these activities. Technological advancements have led to the development of various phytopharmaceutical products, such as spray-dried powders, hydrogels, ointments, granules, films, nanoemulsions, and nanocapsules. The extracts and derivative products from A. satureioides have shown antioxidant, neuroprotective, antidiabetic, antiobesity, antimicrobial, anticancer, and obstructive sleep apnea syndrome effects, indicating its high potential for industrial applications.