期刊
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
卷 -, 期 -, 页码 -出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14787210.2023.2259106
关键词
Africa; antibiotics; antimicrobial resistance; antimicrobial stewardship programmes; AWaRe classification; community pharmacies; over-the-counter purchasing; quality indicators; utilization patterns
Antimicrobial resistance (AMR) is a global concern, especially in Africa where it has the highest mortality rate. High levels of antibiotic dispensing without a prescription are a key driver of AMR. It is necessary to document the current rates of antibiotic dispensing, their reasons, and potential solutions such as antimicrobial stewardship programmes (ASPs). Some African countries have implemented ASPs and quality targets to reduce inappropriate dispensing.
IntroductionAntimicrobial resistance (AMR) is a global concern. Currently, the greatest mortality due to AMR is in Africa. A key driver continues to be high levels of dispensing of antibiotics without a prescription.Areas coveredA need to document current rates of dispensing, their rationale and potential ways forward including antimicrobial stewardship programmes (ASPs). A narrative review was undertaken. The highest rates of antibiotic purchasing were in Eritrea (up to 89.2% of antibiotics dispensed), Ethiopia (up to 87.9%), Nigeria (up to 86.5%), Tanzania (up to 92.3%) and Zambia (up to 100% of pharmacies dispensing antibiotics without a prescription). However, considerable variation was seen with no dispensing in a minority of countries and situations. Key drivers of self-purchasing included high co-payment levels for physician consultations and antibiotic costs, travel costs, convenience of pharmacies, patient requests, limited knowledge of antibiotics and AMR and weak enforcement. ASPs have been introduced in some African countries along with quality targets to reduce inappropriate dispensing, centering on educating pharmacists and patients.Expert OpinionASP activities need accelerating among community pharmacies alongside quality targets, with greater monitoring of pharmacists' activities to reduce inappropriate dispensing. Such activities, alongside educating patients and healthcare professionals, should enhance appropriate dispensing of antibiotics and reduce AMR.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据