4.5 Article

Intrinsic capacity in acutely hospitalized older adults

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Geriatrics & Gerontology

Clinical significance of geriatric conditions in acute hospitalization

Hiroyuki Umegaki et al.

Summary: This study investigated the clinical significance of geriatric conditions (GCs) in acute care for the elderly population. It found that GCs were associated with frailty and polypharmacy, and may lead to readmission after discharge. However, there was no significant association between GCs and the incidence of hospital-acquired complications, falls, or mortality after discharge.

GERIATRICS & GERONTOLOGY INTERNATIONAL (2023)

Article Geriatrics & Gerontology

Plasma inflammation-related biomarkers are associated with intrinsic capacity in community-dwelling older adults

Wan-Hsuan Lu et al.

Summary: This study aimed to investigate the associations between plasma inflammation-related biomarkers and intrinsic capacity (IC) in older adults. The results showed that inflammation was associated with lower IC, and TNFR-1 and GDF-15 were consistently associated with IC at the cross-sectional and longitudinal levels.

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2023)

Article Geriatrics & Gerontology

Intrinsic Capacity Defined Using Four Domains and Mortality Risk: A 5-Year Follow-Up of the SarcoPhAge Cohort

M. Locquet et al.

Summary: The concept of intrinsic capacity, specifically in the domains of mobility and psychological well-being, is crucial for assessing the health and well-being of older adults. Satisfactory levels of intrinsic capacity in these domains are associated with reduced mortality risk. Integration of the concept of intrinsic capacity into clinical practice is recommended for improving the care of older adults.

JOURNAL OF NUTRITION HEALTH & AGING (2022)

Article Geriatrics & Gerontology

Intrinsic Capacity Predicts Negative Health Outcomes in Older Adults

Erwin Stolz et al.

Summary: The study found that intrinsic capacity (IC) declines progressively in older adults and predicts negative health outcomes. Regular monitoring of IC could work as an early warning system to inform preventive efforts, reducing risks such as impaired activities of daily living, long-term nursing home stay, and mortality.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2022)

Article Geriatrics & Gerontology

Intrinsic Capacity: Validation of a New WHO Concept for Healthy Aging in a Longitudinal Chinese Study

John R. Beard et al.

Summary: The study examines the structure of intrinsic capacity in the Chinese elderly population, showing that it consists of five subfactors and can effectively predict declining performance in daily activities. This assessment method provides valuable information beyond traditional factors like age, sex, and education level, demonstrating strong reliability.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2022)

Article Geriatrics & Gerontology

Associations Between Intrinsic Capacity and Adverse Events Among Nursing Home Residents: The INCUR Study

Juan Luis Sanchez-Sanchez et al.

Summary: This study aimed to investigate the associations of intrinsic capacity (IC) and its domains with mortality, hospitalization, pneumonia onset, and functional status decline in nursing home residents (NHRs). The results showed that higher IC levels were associated with lower risk of adverse outcomes.

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION (2022)

Review Cell Biology

Defining and assessing intrinsic capacity in older people: A systematic review and a proposed scoring system

Susana Lopez-Ortiz et al.

Summary: This study aims to review the definitions and methods used for the assessment of intrinsic capacity (IC) in older adults. While there is overall consensus on the definition and dimensions of IC, there is substantial variation in the assessment methods, and no consensus on the best way to compute a comprehensive score to evaluate IC.

AGEING RESEARCH REVIEWS (2022)

Article Geriatrics & Gerontology

Longitudinal trajectories of intrinsic capacity and their association with quality of life and disability

Aaron Salinas-Rodriguez et al.

Summary: This study investigates the longitudinal trajectories of intrinsic capacity (IC) in older Mexican adults and their associations with quality of life and disability. The findings highlight the importance of health policies and strategies to maintain intrinsic capacity and promote primary prevention.

MATURITAS (2022)

Review Geriatrics & Gerontology

Intrinsic capacity and 10-year mortality: Findings from a cohort of older people

Ruby Yu et al.

Summary: This study tracked a cohort of 2032 Chinese individuals aged 70 years and older, and found an association between intrinsic capacity (IC) and 10-year mortality. After adjusting for sociodemographic variables and past medical illnesses, higher IC was associated with a lower risk of mortality. Therefore, assessment of IC should be implemented in community and institutional settings for early interventions.

EXPERIMENTAL GERONTOLOGY (2022)

Article Geriatrics & Gerontology

Muscle Evaluation and Hospital-Associated Disability in Acute Hospitalized Older Adults

M. Nagae et al.

Summary: This study aimed to examine the association between muscle evaluation and hospital-associated disability (HAD), and found that thigh muscle thickness (BATT) was independently associated with mobility impairments, while other muscle indicators showed no significant association with self-care impairments. Therefore, it is necessary to reconsider muscle assessment methods in hospitalized older adults and consider comprehensive interventions to improve self-care.

JOURNAL OF NUTRITION HEALTH & AGING (2022)

Article Geriatrics & Gerontology

The Impact of Intrinsic Capacity on Adverse Outcomes in Older Hospitalized Patients: A One-Year Follow-Up Study

Xingkun Zeng et al.

Summary: This study focused on the impact of Intrinsic Capacity (IC) domains on adverse health outcomes including new activities of daily living (ADL) dependency, new instrumental activities of daily living (IADL) dependency, and mortality among older hospitalized Chinese adults over a 1-year follow-up period. Results showed that higher IC composite score at admission was associated with decreased risks of ADL dependency, IADL dependency, and mortality after one year. Additionally, lower Mini-Mental State Examination (MMSE) scores at admission predicted new ADL and IADL dependency among older hospitalized patients.

GERONTOLOGY (2021)

Article Geriatrics & Gerontology

Intrinsic Capacity as a Determinant of Physical Resilience in Older Adults

J. K. Chhetri et al.

Summary: The traditional disease-oriented model of healthcare is inadequate for older populations, greater focus on healthy aging strategies is needed. The concepts of intrinsic capacity (IC) and physical resilience (PR) have the potential to reshape geriatric medicine and aging research. IC encompasses all physical and mental capacities, while PR is the ability to successfully cope with stressors.

JOURNAL OF NUTRITION HEALTH & AGING (2021)

Review Geriatrics & Gerontology

A Rapid Review of the Measurement of Intrinsic Capacity in Older Adults

Pradeep Paul George et al.

Summary: This study identified significant variations in measurement instruments and processes used to assess intrinsic capacity, especially in the vitality and psychological domains. A standardized intrinsic capacity composite score for clinical or community settings has not been established yet. Further validation through prospective studies of the intrinsic capacity concept and computation of composite score using validated scales is necessary.

JOURNAL OF NUTRITION HEALTH & AGING (2021)

Article Geriatrics & Gerontology

Echo intensity is more useful in predicting hospital-associated complications than conventional sarcopenia-related parameters in acute hospitalized older patients

Masaaki Nagae et al.

Summary: Corrected echo intensity may be a useful parameter to predict hospital-associated complications in acute hospitalized older patients, while handgrip strength, muscle thickness, skeletal muscle index, and calf circumference were not found to be associated.

EXPERIMENTAL GERONTOLOGY (2021)

Review Geriatrics & Gerontology

Prevalence of Hospital-Associated Disability in Older Adults: A Meta-analysis

Christine Loyd et al.

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION (2020)

Article Geriatrics & Gerontology

Prediction of Adverse Outcomes in Nursing Home Residents According to Intrinsic Capacity Proposed by the World Health Organization

Alexia Charles et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2020)

Article Geriatrics & Gerontology

ALLOSTATIC LOAD AS A BIOLOGICAL SUBSTRATE TO INTRINSIC CAPACITY: A SECONDARY ANALYSIS OF CRELES

L. M. Gutierrez-Robledo et al.

JOURNAL OF NUTRITION HEALTH & AGING (2019)

Article Medicine, General & Internal

Management of frailty: opportunities, challenges, and future directions

Elsa Dent et al.

LANCET (2019)

Editorial Material Medicine, General & Internal

PHYSICAL FRAILTY: A BIOLOGICAL MARKER OF AGING?

John E. Morley

BMJ OPEN (2019)

Article Geriatrics & Gerontology

Hospital-Associated Complications of Older People: A Proposed Multicomponent Outcome for Acute Care

Alison M. Mudge et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2019)

Article Geriatrics & Gerontology

Prevalence of and factors associated with prolonged length of stay in older hospitalized medical patients

Mario Bo et al.

GERIATRICS & GERONTOLOGY INTERNATIONAL (2016)

Article Geriatrics & Gerontology

Hospital-Associated Functional Decline: The Role of Hospitalization Processes Beyond Individual Risk Factors

Anna Zisberg et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2015)

Review Medicine, General & Internal

Delirium in elderly people

Sharon K. Inouye et al.

LANCET (2014)

Article Medicine, General & Internal

Hospitalization-Associated Disability She Was Probably Able to Ambulate, but I'm Not Sure

Kenneth E. Covinsky et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2011)

Article Geriatrics & Gerontology

Recovery of Activities of Daily Living in Older Adults After Hospitalization for Acute Medical Illness

Cynthia M. Boyd et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2008)

Article Geriatrics & Gerontology

Screening for undernutrition in geriatric practice:: Developing the Short-Form Mini-Nutritional Assessment (MNA-SF)

LZ Rubenstein et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2001)