Impact of prostate imaging quality (PI-QUAL) score on the detection of clinically significant prostate cancer at biopsy

Article Urology & Nephrology

Role of the Prostate Imaging Quality PI-QUAL Score for Prostate Magnetic Resonance Image Quality in Pathological Upstaging After Radical Prostatectomy: A Multicentre European Study

Olivier Windisch et al.

Summary: PI-QUAL <3 is associated with higher rate of disease upstaging, lower detection rates of PI-RADS 5 lesions and suspicious lesions, and lower detection rates of extraprostatic extension.

EUROPEAN UROLOGY OPEN SCIENCE (2023)

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Article Radiology, Nuclear Medicine & Medical Imaging

Prostate MRI quality: clinical impact of the PI-QUAL score in prostate cancer diagnostic work-up

Eleftherios Karanasios et al.

Summary: Higher PI-QUAL scores are associated with decreased uncertainty in MRI decision-making and improved efficiency of diagnostic pathway delivery. The study demonstrates moderate inter-reader agreement for PI-QUAL scoring and validates the score in a clinical setting, showing correlation of image quality with PI-RADS score, number of biopsy procedures, and need for repeat imaging.

BRITISH JOURNAL OF RADIOLOGY (2022)

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Article Radiology, Nuclear Medicine & Medical Imaging

Rectal preparation significantly improves prostate imaging quality: Assessment of the PI-QUAL score with visual grading characteristics

Michael A. Arnoldner et al.

Summary: The study investigated the effects of a rectal preparation regimen on prostate imaging quality. The results showed that rectal preparation significantly improved general image quality and lesion visibility.

EUROPEAN JOURNAL OF RADIOLOGY (2022)

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Article Medicine, General & Internal

Diagnostic Accuracy of Abbreviated Bi-Parametric MRI (a-bpMRI) for Prostate Cancer Detection and Screening: A Multi-Reader Study

Giorgio Brembilla et al.

Summary: The study found that abbreviated biparametric MRI protocols can match the diagnostic accuracy of standard biparametric MRI and multiparametric MRI for detecting clinically significant prostate cancer. When used in low-prevalence settings, higher cut-offs for MRI positivity should be prioritized.

DIAGNOSTICS (2022)

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Review Radiology, Nuclear Medicine & Medical Imaging

Prostate MRI quality: a critical review of the last 5 years and the role of the PI-QUAL score

Francesco Giganti et al.

Summary: There is growing interest in using multiparametric magnetic resonance imaging (mpMRI) in the prostate cancer pathway. This critical review summarizes recent studies aimed at improving prostate MR quality, including the use of specific MR sequences, magnets and coils, and patient preparation. The article also discusses the adherence rates of technical standards for prostate mpMRI in different cohorts worldwide, as well as the development of a standardized scoring system for evaluating image quality.

BRITISH JOURNAL OF RADIOLOGY (2022)

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Article Radiology, Nuclear Medicine & Medical Imaging

Inter-reader agreement of the PI-QUAL score for prostate MRI quality in the NeuroSAFE PROOF trial

Francesco Giganti et al.

Summary: The study investigated the inter-reader reproducibility of the Prostate Imaging Quality (PI-QUAL) score in patients enrolled in the NeuroSAFE PROOF trial, with results showing strong agreement between two experienced radiologists. The highest agreement in terms of diagnostic quality was observed for T2-weighted imaging.

EUROPEAN RADIOLOGY (2022)

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Article Radiology, Nuclear Medicine & Medical Imaging

Inter-reader agreement of the Prostate Imaging Quality (PI-QUAL) score: A bicentric study

Rossano Girometti et al.

Summary: This study investigated the inter-reader agreement of Prostate imaging quality (PI-QUAL) assessment for multiparametric magnetic resonance imaging (mpMRI). The results showed that the reproducibility of PI-QUAL was moderate, and higher PI-QUAL scores were associated with excellent inter-reader agreement for PI-RADSv2.1 categorization.

EUROPEAN JOURNAL OF RADIOLOGY (2022)

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Article Radiology, Nuclear Medicine & Medical Imaging

Impact of PI-QUAL on PI-RADS and cancer yield in an MRI-TRUS fusion biopsy population*

N. Poetsch et al.

Summary: The study aims to test the inter-reader agreement of the Prostate Imaging Quality (PI-QUAL) score for multiparametric prostate MRI and its impact on diagnostic performance in an MRI-ultrasound fusion biopsy population. The results show that PI-QUAL score has limited impact on PI-RADS diagnostic performance, but lower PI-QUAL scores may lead to false-positive referrals and unnecessary biopsies.

EUROPEAN JOURNAL OF RADIOLOGY (2022)

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Review Oncology

Positive Predictive Value of Prostate Imaging Reporting and Data System Version 2 for the Detection of Clinically Significant Prostate Cancer: A Systematic Review and Meta-analysis

Elio Mazzone et al.

Summary: This meta-analysis found that the PPV of mpMRI is highly dependent on disease prevalence, with main factors affecting PPV being PI-RADS version 2 scores and prior biopsy status. PPV for csPCa increased with higher PI-RADS scores and was influenced by cancer prevalence. Study design, TBx technique, and number of sampled cores did not affect PPV significantly.

EUROPEAN UROLOGY ONCOLOGY (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging