Hypertension and myocarditis following COVID-19 vaccination. Two sides of the coin?

Editorial Material Medicine, General & Internal

The relationship between COVID-19 vaccines and increased blood pressure: A word of caution

Giacomo Buso et al.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2023)

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Letter Medicine, General & Internal

COVID-19 vaccines and increased blood pressure

Amnuay Kleebayoon et al.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2023)

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Article Multidisciplinary Sciences

SARS-CoV-2 vaccine protection and deaths among US veterans during 2021

Barbara A. Cohn et al.

Summary: This study reports the effectiveness of vaccines against SARS-CoV-2 infection and death in veterans, with a decline in vaccine effectiveness observed for all vaccine types. The decline was greatest for the Janssen vaccine. However, vaccination remained protective against death for individuals who became infected during the Delta variant surge. The study also found variations in the vaccine effectiveness against death among different age groups.

SCIENCE (2022)

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Review Medicine, General & Internal

COVID-19, vaccines and deficiency of ACE2 and other angiotensinases. Closing the loop on the Spike effect

Fabio Angeli et al.

Summary: The dysregulation of the renin-angiotensin system (RAS) plays a significant role in the pathogenesis of COVID-19, primarily due to the imbalance between angiotensin II and angiotensin(1-7) caused by the interaction between SARS-CoV-2 and ACE(2) receptors. Understanding the mechanisms of Ang II cleavage and accumulation provides insights into the risk of severe COVID-19 and potential adverse reactions to vaccination.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2022)

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Letter Medicine, General & Internal

Antibody Responses in Seropositive Persons after a Single Dose of SARS-CoV-2 mRNA Vaccine

Florian Krammer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Review Medicine, General & Internal

SARS-CoV-2 vaccines: Lights and shadows

Fabio Angeli et al.

Summary: SARS-CoV-2 vaccines can elicit immune responses but concerns about cardiovascular adverse reactions have been raised. Vaccines can increase Spike protein synthesis and immune responses, with genetic and immunological factors possibly impacting reactions.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2021)

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Article Cardiac & Cardiovascular Systems

Myocarditis With COVID-19 mRNA Vaccines

Biykem Bozkurt et al.

Summary: Myocarditis is a rare complication of COVID-19 mRNA vaccines, predominantly affecting young adult and adolescent males, with most patients showing improvement in symptoms. Possible mechanisms include molecular mimicry between viral proteins and self-antigens, dysregulated immune pathways, immune response to mRNA, and dysregulated cytokine expression.

CIRCULATION (2021)

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Review Medicine, General & Internal

The pivotal link between ACE2 deficiency and SARS-CoV-2 infection: One year later

Fabio Angeli et al.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2021)

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Letter Medicine, General & Internal

Blood pressure increase after Pfizer/BioNTech SARS-CoV-2 vaccine

Martina Zappa et al.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2021)

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Hypertension and myocarditis following COVID-19 vaccination. Two sides of the coin?

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