4.6 Review

The socioeconomic burden of acromegaly

期刊

EUROPEAN JOURNAL OF ENDOCRINOLOGY
卷 189, 期 2, 页码 R1-R10

出版社

OXFORD UNIV PRESS
DOI: 10.1093/ejendo/lvad097

关键词

acromegaly; pituitary; socioeconomic burden; quality of life; disability; absenteeism; cost of illness

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Acromegaly is a rare disease characterized by chronic excess growth hormone, causing various morphological changes and complications. It imposes a significant socioeconomic burden and affects the quality of life of patients. This review provides a comprehensive understanding of the psychosocial burden, impact on daily life, and cost of acromegaly, as well as management strategies and interventions to improve treatment and care.
Acromegaly is a rare and insidious disease characterized by chronic excess growth hormone, leading to various morphological changes and systemic complications. Despite its low prevalence, acromegaly poses a significant socioeconomic burden on patients and healthcare systems. This review synthesizes the current state of knowledge on the psychosocial burden, disability, impact on daily life, and cost of acromegaly disease, focusing on the quality of life, partnership, medical care and treatment afflictions, participation in daily activities, professional and leisure impairment, and cost of treatment for acromegaly and its comorbidities. It also examines management strategies, coping mechanisms, and interventions aimed at alleviating this burden. A comprehensive understanding of the extent of the socioeconomic burden in acromegaly is crucial to develop effective strategies to improve treatment and care. Further research is warranted to explore the myriad factors contributing to this burden, as well as the efficacy of interventions to alleviate it, ultimately enhancing the quality of life for patients with acromegaly.

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