4.5 Review

A systematic review of the use of bacteriophages for in vitro biofilm control

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Hydrodynamics and surface properties influence biofilm proliferation

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Summary: Staphylococcus aureus is a priority pathogen due to its increasing antibiotic resistance, and it can form stubborn biofilms. Bacteriophages and their lysins may be a strategy to combat staphylococcal biofilms, with the combination of the lytic protein CHAPSH3b and bacteriophage phiIPLA-RODI showing synergy in reducing bacterial counts and limiting regrowth. This combination also demonstrated promising results in an ex vivo pig skin model.

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Development of thermosensitive hydrogel wound dressing containing Acinetobacter baumannii phage against wound infections

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