4.7 Article

Epidemiologic roadblocks in studying elongated mineral particles and mesothelioma risk

期刊

ENVIRONMENTAL RESEARCH
卷 230, 期 -, 页码 -

出版社

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.envres.2022.115086

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Elongated particles; Mesothelioma; Epidemiology; Risk assessment

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Elongated mineral particles (EMPs) have attracted scientific interest due to their potential health effects and possible association with mesothelioma. This article provides an overview of current challenges in epidemiological assessments of EMP exposure and mesothelioma risk, including methodological aspects that need to be addressed in study design and analysis. Future research should focus on improving the definition of EMP exposure and accounting for other concurrent sources of carcinogen exposure when investigating the relationship between EMPs and mesothelioma.
Elongated mineral particles (EMPs) are a type of both occupational and environmental exposures that have generated interest in the scientific community due to their potential health effects. Their possible association with mesothelioma represents an area of concern. We provide an overview of the current challenges around epidemiological assessments of EMP exposure and mesothelioma risk, including methodological aspects that need to be addressed when designing and analyzing a study on EMP exposure and mesothelioma. Future work is needed to investigate the relationship between EMPs and mesothelioma, focused on an improved definition of EMP exposure and accounting for other concomitant sources of carcinogen exposure.

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