期刊
CHEMICAL COMMUNICATIONS
卷 51, 期 31, 页码 6832-6835出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc01393c
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资金
- National Basic Research Program of China [2014CB846004]
- National Natural Science Foundation of China [91227106, 21202083, 21302092]
- National Science Foundation of Jiangsu [BK20140595]
Novel GSH- and pH-responsive supramolecular vesicles constructed by an amphiphilic inclusion complex formed from water-soluble pillar[5]arene and lysine derivative have been successfully developed, which can efficiently encapsulate anticancer drug MTZ and show rapid MTZ-release in a simulated acidic tumor environment with high GSH concentration, and exhibit potent antitumor activity.
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