4.7 Article

Cancer-cell-secreted extracellular vesicles target p53 to impair mitochondrial function in muscle

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell Biology

Cancer-cell-secreted miR-122 suppresses O-GlcNAcylation to promote skeletal muscle proteolysis

Wei Yan et al.

Summary: Breast cancer suppresses O-GlcNAc protein modification in muscle through miR-122, leading to dysregulated skeletal muscle proteolysis with aberrant Ca2+ levels and calpain protease activation.

NATURE CELL BIOLOGY (2022)

Article Cell Biology

Cancer-cell-secreted extracellular vesicles suppress insulin secretion through miR-122 to impair systemic glucose homeostasis and contribute to tumour growth

Minghui Cao et al.

Summary: Breast cancer-derived extracellular vesicles suppress pancreatic insulin secretion, leading to dysregulated glucose homeostasis and enhanced tumor growth by targeting PKM in beta-cells.

NATURE CELL BIOLOGY (2022)

Article Biochemistry & Molecular Biology

miR-122-5p negatively regulates the transforming growth factor-β/Smad signaling pathway in skeletal muscle myogenesis

Zheci Ding et al.

CELL BIOCHEMISTRY AND FUNCTION (2020)

Review Physiology

Maintenance of Skeletal Muscle Mitochondria in Health, Exercise, and Aging

David A. Hood et al.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 81 (2019)

Review Health Care Sciences & Services

Emerging Treatment Options For Cancer-Associated Cachexia: A Literature Review

Tateaki Naito

THERAPEUTICS AND CLINICAL RISK MANAGEMENT (2019)

Article Oncology

Cancer Statistics, 2018

Rebecca L. Siegel et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2018)

Review Nutrition & Dietetics

Prevalence and predictive value of pre-therapeutic sarcopenia in cancer patients: A systematic review

Frederic Pamoukdjian et al.

CLINICAL NUTRITION (2018)

Article Medicine, Research & Experimental

miR-24 and miR-122 Negatively Regulate the Transforming Growth Factor-β/Smad Signaling Pathway in Skeletal Muscle Fibrosis

Yaying Sun et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2018)

Article Multidisciplinary Sciences

Broad role for YBX1 in defining the small noncoding RNA composition of exosomes

Matthew J. Shurtleff et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90

Guohua Zhang et al.

NATURE COMMUNICATIONS (2017)

Review Biochemistry & Molecular Biology

Mitochondria and Cancer

Sejal Vyas et al.

Article Medicine, Research & Experimental

Autophagy and p53

Eileen White

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2016)

Article Cell Biology

Effect of p53 on mitochondrial morphology, import, and assembly in skeletal muscle

Ayesha Saleem et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2015)

Article Biochemistry & Molecular Biology

Excess TGF-β mediates muscle weakness associated with bone metastases in mice

David L. Waning et al.

NATURE MEDICINE (2015)

Review Endocrinology & Metabolism

Mitochondrial dysfunction and insulin resistance: an update

Magdalene K. Montgomery et al.

ENDOCRINE CONNECTIONS (2015)

Article Multidisciplinary Sciences

Microvesicles containing miRNAs promote muscle cell death in cancer cachexia via TLR7

Wei A. He et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Oncology

Cancer cachexia: understanding the molecular basis

Josep M. Argiles et al.

NATURE REVIEWS CANCER (2014)

Article Biochemistry & Molecular Biology

p53 Orchestrates the PGC-1α-Mediated Antioxidant Response Upon Mild Redox and Metabolic Imbalance

Katia Aquilano et al.

ANTIOXIDANTS & REDOX SIGNALING (2013)

Review Cell Biology

Metabolic Regulation by p53 Family Members

Celia R. Berkers et al.

CELL METABOLISM (2013)

Review Oncology

Understanding the mechanisms and treatment options in cancer cachexia

Kenneth Fearon et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2013)

Article Biochemistry & Molecular Biology

A PGC-1α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy

Jorge L. Ruas et al.

Review Cell Biology

Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways

Kenneth C. H. Fearon et al.

CELL METABOLISM (2012)

Article Medicine, Research & Experimental

De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer

Xiwei Wu et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2012)

Article Oncology

Prevalence and prognostic effect of sarcopenia in breast cancer survivors: the HEAL Study

Adriana Villasenor et al.

JOURNAL OF CANCER SURVIVORSHIP (2012)

Article Cell Biology

Rab27a and Rab27b control different steps of the exosome secretion pathway

Matias Ostrowski et al.

NATURE CELL BIOLOGY (2010)

Review Biochemistry & Molecular Biology

Mitochondrial calcium as a key regulator of mitochondrial ATP production in mammalian cells

Elinor J. Griffiths et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2009)

Article Biochemistry & Molecular Biology

The mitochondrial p53 pathway

Angelina V. Vaseva et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2009)

Review Biochemistry & Molecular Biology

Modes of p53 Regulation

Jan-Philipp Kruse et al.

Article Cardiac & Cardiovascular Systems

p53 Improves Aerobic Exercise Capacity and Augments Skeletal Muscle Mitochondrial DNA Content

Joon-Young Park et al.

CIRCULATION RESEARCH (2009)

Article Cell Biology

Role of p53 in mitochondrial biogenesis and apoptosis in skeletal muscle

Ayesha Saleem et al.

PHYSIOLOGICAL GENOMICS (2009)

Article Oncology

Estimation of Cachexia among Cancer Patients Based on Four Definitions

Kathleen M. Fox et al.

JOURNAL OF ONCOLOGY (2009)

Review Oncology

The first 30 years of p53: growing ever more complex

Arnold J. Levine et al.

NATURE REVIEWS CANCER (2009)

Article Cell Biology

Regulation of autophagy by cytoplasmic p53

Ezgi Tasdemir et al.

NATURE CELL BIOLOGY (2008)

Article Multidisciplinary Sciences

p53 regulates mitochondrial respiration

Satoaki Matoba et al.

SCIENCE (2006)

Review Biochemical Research Methods

Ballistic labeling and dynamic imaging of astrocytes in orcranotypic hippocampal slice cultures

AM Benediktsson et al.

JOURNAL OF NEUROSCIENCE METHODS (2005)

Article Biochemistry & Molecular Biology

Direct influence of the p53 tumor suppressor on mitochondrial biogenesis and function

RJ Donahue et al.

FASEB JOURNAL (2001)