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Transcription factors Sp1 and Sp3 regulate expression of human ABCG2 gene and chemoresistance phenotype
Wook-Jin Yang et al.
MOLECULES AND CELLS (2013)
Correction: Resveratrol as a Pan-HDAC Inhibitor Alters the Acetylation Status of Jistone Proteins in Human-Derived Hepatoblastoma Cells
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PLoS One (2013)
Oroxylin A reverses P-glycoprotein-mediated multidrug resistance of MCF7/ADR cells by G2/M arrest
Litao Zhu et al.
TOXICOLOGY LETTERS (2013)
Tropolones As Lead-Like Natural Products: The Development of Potent and Selective Histone Deacetylase Inhibitors
Sophia N. Ononye et al.
ACS MEDICINAL CHEMISTRY LETTERS (2013)
Dual regulation of P-glycoprotein expression by Trichostatin A in cancer cell lines
Trinidad Mata Balaguer et al.
BMC MOLECULAR BIOLOGY (2012)
Lycorine induces cell-cycle arrest in the G0/G1 phase in K562 cells via HDAC inhibition
Lv Li et al.
CANCER CELL INTERNATIONAL (2012)
Genistein inhibits the sternness properties of prostate cancer cells through targeting Hedgehog-Gli1 pathway
Linlin Zhang et al.
CANCER LETTERS (2012)
Curcumin Analogue CDF Inhibits Pancreatic Tumor Growth by Switching on Suppressor microRNAs and Attenuating EZH2 Expression
Bin Bao et al.
CANCER RESEARCH (2012)
Hypoxia-Inducible Factors in Physiology and Medicine
Gregg L. Semenza
CELL (2012)
Fucoxanthin Attenuates Rifampin-Induced Cytochrome P450 3A4 (CYP3A4) and Multiple Drug Resistance 1 (MDR1) Gene Expression Through Pregnane X Receptor (PXR)-Mediated Pathways in Human Hepatoma HepG2 and Colon Adenocarcinoma LS174T Cells
Cheng-Ling Liu et al.
MARINE DRUGS (2012)
Tumor cycling hypoxia induces chemoresistance in glioblastoma multiforme by upregulating the expression and function of ABCB1
Chii-Wen Chou et al.
NEURO-ONCOLOGY (2012)
Tetrandrine enhances cytotoxicity of cisplatin in human drug-resistant esophageal squamous carcinoma cells by inhibition of multidrug resistance-associated protein 1
Tian Hu Wang et al.
ONCOLOGY REPORTS (2012)
The Effect of Vorinostat on the Development of Resistance to Doxorubicin in Neuroblastoma
Timothy B. Lautz et al.
PLOS ONE (2012)
Co-administration of piperine and docetaxel results in improved anti-tumor efficacy via inhibition of CYP3A4 activity
Peter Makhov et al.
PROSTATE (2012)
Effects of Baicalein on the Pharmacokinetics of Tamoxifen and its Main Metabolite, 4-Hydroxytamoxifen, in Rats: Possible Role of Cytochrome P450 3A4 and P-glycoprotein inhibition by Baicalein
Cheng Li et al.
ARCHIVES OF PHARMACAL RESEARCH (2011)
HDAC inhibitors downregulate MRP2 expression in multidrug resistant cancer cells: Implication for chemosensitization
Hanna Kim et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2011)
Inhibitory effect of caffeic acid on cancer cell proliferation by oxidative mechanism in human HT-1080 fibrosarcoma cell line
N. Rajendra Prasad et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2011)
ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma
R. R. Singh et al.
ONCOGENE (2011)
Increased antitumor efficacy by the combined administration of swainsonine and cisplatin in vivo
Felipe M. Santos et al.
PHYTOMEDICINE (2011)
Piperine, a piperidine alkaloid from Piper nigrum re-sensitizes P-gp, MRP1 and BCRP dependent multidrug resistant cancer cells
Sen Li et al.
PHYTOMEDICINE (2011)
Notch1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cells
Sungpil Cho et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Triptolide circumvents drug-resistant effect and enhances 5-fluorouracil antitumor effect on KB cells
Yuan-Wu Chen et al.
ANTI-CANCER DRUGS (2010)
Targeting Notch signaling pathway to overcome drug resistance for cancer therapy
Zhiwei Wang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2010)
Tetrandrine prevents acquired drug resistance of K562 cells through inhibition of mdr1 gene transcription
Huiling Shen et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2010)
(-)-Epigallocatechin-3-gallate downregulates Pg-P and BCRP in a tamoxifen resistant MCF-7 cell line
F. Farabegoli et al.
PHYTOMEDICINE (2010)
Orphan Nuclear Receptors as Targets for Drug Development
Subhajit Mukherjee et al.
PHARMACEUTICAL RESEARCH (2010)
Inhibition of P-Glycoprotein by Wogonin Is Involved with the Potentiation of Etoposide-Induced Apoptosis in Cancer Cells
Eibai Lee et al.
NATURAL COMPOUNDS AND THEIR ROLE IN APOPTOTIC CELL SIGNALING PATHWAYS (2009)
Histone Deacetylase Inhibitors Induce a Very Broad, Pleiotropic Anticancer Drug Resistance Phenotype in Acute Myeloid Leukemia Cells by Modulation of Multiple ABC Transporter Genes
Stefanie Hauswald et al.
CLINICAL CANCER RESEARCH (2009)
Elucidating the 'Jekyll and Hyde' Nature of PXR: The Case for Discovering Antagonists or Allosteric Antagonists
Arunima Biswas et al.
PHARMACEUTICAL RESEARCH (2009)
Pregnane X Receptor and its Potential Role in Drug Resistance in Cancer Treatment
Yakun Chen et al.
RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY (2009)
Tumour Hypoxia Affects the Responsiveness of Cancer Cells to Chemotherapy and Promotes Cancer Progression
Jean-Philippe Cosse et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2008)
STAT3 inhibits the degradation of HIF-1α by pVHL-mediated ubiquitination
Joo Eun Jung et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2008)
Activation of β-catenin signalling by GSK-3 inhibition increases p-glycoprotein expression in brain endothelial cells
Joseph C. Lim et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Histone modifications at the ABCG2 promoter following treatment with histone deacetylase inhibitor mirror those in multidrug-resistant cells
Kenneth K. W. To et al.
MOLECULAR CANCER RESEARCH (2008)
Tumor suppressor LATS1 is a negative regulator of oncogene YAP
Yawei Hao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Elucidation of a universal size-control mechanism in Drosophila and mammals
Jixin Dong et al.
CELL (2007)
The histone deacetylase inhibitor trichostatin A downregulates human MDR1 (ABCB1) gene expression by a transcription-dependent mechanism in a drug-resistant small cell lung carcinoma cell line model
V. El-Khoury et al.
BRITISH JOURNAL OF CANCER (2007)
Structural basis for depletion of heat shock protein 90 client proteins by deguelin
Seung Hyun Oh et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2007)
Effects of herbal medicinal products and food supplements on induction of CYP1A2, CYP3A4 and MDR1 in the human colon carcinoma cell line LS180
Helena Brandin et al.
PHYTOTHERAPY RESEARCH (2007)
Chrysin inhibits expression of hypoxia-inducible factor-1 alpha through reducing hypoxia-inducible factor-1 alpha stability and inhibiting its protein synthesis
Beibei Fu et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Transporters on demand: Intracellular reservoirs and cycling of bile canalicular ABC transporters
Yoshiyuki Wakabayashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Increased MDR1 expression in normal and malignant peripheral blood mononuclear cells obtained from patients receiving depsipeptide (FR901228, FK228, NSC630176)
RW Robey et al.
CLINICAL CANCER RESEARCH (2006)
Transcriptional repression of protein kinase Cα via Sp1 by wild type p53 is involved in inhibition of multidrug resistance 1 P-glycoprotein phosphorylation
MC Zhan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Diallyl disulfide (DADS) increases histone acetylation and p21waf1/cip1 expression in human colon tumor cell lines
N Druesne et al.
CARCINOGENESIS (2004)
The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme
P Krishnamurthy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
P-glycoprotein: from genomics to mechanism
SV Ambudkar et al.
ONCOGENE (2003)
Transcriptional regulation of ABC drug transporters
KW Scotto
ONCOGENE (2003)
Multidrug resistance genes and P-glycoprotein in the testis of the rat, mouse, guinea pig, and human
N Melaine et al.
BIOLOGY OF REPRODUCTION (2002)
Multidrug resistance in cancer: Role of ATP-dependent transporters
MM Gottesman et al.
NATURE REVIEWS CANCER (2002)
Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1
J Sampath et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
P Jaakkola et al.
SCIENCE (2001)