Development and validation of a real-time PCR test to detect Bartonella quintana in clinical samples

This study reports on the validation of a real-time polymerase chain reaction test targeting the vomp region of Bartonella quintana. The assay displayed 100% sensitivity and specificity for the 52 bloods and 159 cultures tested. Molecular diagnosis of Bartonella quintana can aid clinical treatment during acute infection.Published by Elsevier Inc.

Automated summary

This study validates a real-time polymerase chain reaction test for Bartonella quintana by targeting the vomp region. The assay showed 100% sensitivity and specificity in detecting the bacteria in 52 blood samples and 159 cultures. Molecular diagnosis of Bartonella quintana can improve clinical treatment during acute infections.