Biosensors for natriuretic peptides in cardiovascular diseases. A review

Heart failure (HF) is a complex clinical syndrome associated with high rates of morbidity and mortality. Over the years, it has been crucial to find accurate biomarkers capable of doing a precise monitor of HF and provide an early diagnosis. Of these, it has been established an important role of natriuretic peptides in HF assessment. Moreover, the development of biosensors has been garnering interest as new diagnostic medical tools. In this review we first provide a general overview of HF, its pathogenesis, and diagnostic features. We then discuss the role of natriuretic peptides in heart failure by characterizing them and point out their potential as biomarkers. Finally, we adress the evolution of biosensors development and the available natriuretic peptides biosensors for disease monitoring.

Automated summary

Heart failure (HF) is a complex clinical syndrome with high morbidity and mortality rates. Accurate biomarkers for monitoring and early diagnosis of HF are crucial. Natriuretic peptides have been established to play an important role in HF assessment, and the development of biosensors has provided new diagnostic tools. This review provides an overview of HF, natriuretic peptides, and the development and application of biosensors.