Noncompaction Cardiomyopathy : Issues, Contradictions and Search for Effective Diagnostic Criteria. Literature Review. Part 2

Active research of noncompaction cardiomyopathy (NCM) has been going on for more than 30 years. A significant amount of information has been accumulated that is familiar to a much larger number of specialists than in the most recent past. Despite this, numerous issues remain unresolved, ranging from classification (congenital or acquired, nosology, or morphological phenotype) to the ongoing search for clear diagnostic criteria that separate NCM from compaction myocardium with the background of existing chronic processes. Meanwhile, a high risk of adverse cardiovascular events in a certain group of people with NCM is quite high. These patients need timely and often quite aggressive therapy. This review of sources of scientific and practical information is devoted to the current aspects of the classification, extremely diverse clinical picture, extremely complex genetic, and instrumental diagnosis of NCM, and the possibilities of its treatment. The purpose of this review is to analyze current ideas about the controver-sial problems of noncompaction cardiomyopathy. The material for its preparation is the numerous sources of databases Web Science, PubMed, Google Scholar, eLI-BRARY. As a result of their analysis, the authors tried to identify and summarize the main problems of the NCM and identify the ways to resolve them. (Curr Probl Cardiol 2023;48:101723.)

Automated summary

Active research on noncompaction cardiomyopathy (NCM) has been conducted for over 30 years, accumulating a significant amount of information. However, many issues regarding classification, diagnostic criteria, and treatment remain unresolved. NCM patients face a high risk of adverse cardiovascular events and require timely and aggressive therapy. This review aims to analyze current perspectives on NCM and propose solutions to the controversial problems, based on extensive analysis of various scientific databases.