Venous External Support in Coronary Artery Bypass Surgery: A Systematic Review and Meta-Analysis

Neointimal hyperplasia and lumen irregularities are major contributors to vein graft failure and the use of VEST(R) should prevent this. In this review, we aim to evaluate the angiographic outcomes of externally supported vein grafts. Medline, Embase and Cochrane Library were systematically reviewed for randomized clinical trials published by August 2022. The primary outcome was graft failure. Secondary outcomes included graft ectasia, intimal hyperplasia area and thickness, and graft nonuniformity. Odds ratios (OR) for dichotomous variables and mean difference (MD) for continuous variables with 95% confidence intervals (CI) were pooled using a fixed-effects model. Three randomized controlled trials with a total of 437 patients were included with follow-up ranging

Automated summary

This review aims to evaluate the angiographic outcomes of externally supported vein grafts and the preventive effect of using VEST(R) on neointimal hyperplasia and lumen irregularities. Randomized clinical trials published by August 2022 were systematically reviewed using Medline, Embase, and Cochrane Library. The primary outcome was graft failure, while secondary outcomes included graft ectasia, intimal hyperplasia area and thickness, and graft nonuniformity. Odds ratios (OR) and mean difference (MD) with 95% confidence intervals (CI) were pooled using a fixed-effects model. Three randomized controlled trials involving 437 patients were included with varying follow-up periods.