4.2 Review

Dietary fiber deficiency in individuals with metabolic syndrome: a review

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Review Biochemistry & Molecular Biology

Gut Microbiota and Short Chain Fatty Acids: Implications in Glucose Homeostasis

Piero Portincasa et al.

Summary: The gut microbiota consists of trillions of commensal microorganisms including bacteria, fungi, and viruses, which coexist in symbiosis with the host and have profound effects on human health. Short chain fatty acids (SCFAs) are the most abundant bacterial metabolites in the human body and play an important role in metabolic, endocrine, and immune functions. Diet can influence the composition and activity of the gut microbiota, as well as SCFAs production and metabolic effects.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Microbiology

Global, distinctive, and personal changes in molecular and microbial profiles by specific fibers in humans

Samuel M. Lancaster et al.

Summary: Dietary fibers play a role in improving cardiovascular health, preventing metabolic disorders and cancer through their impact on the microbiome. This study examined the effects of different types of fibers on various markers, including metabolomics, lipidomics, proteomics, metagenomics, cytokine panel, and clinical measurements. Each fiber showed fiber-dependent biochemical and microbial responses. Arabinoxylan (AX) intake was associated with reduced LDL and increased bile acids, contributing to cholesterol reduction. Long-chain inulin (LCI) intake led to an increase in Bifidobacterium, but at high doses, it also caused inflammation and elevated liver enzyme levels. This study provides insights into the mechanisms of fiber-induced cholesterol reduction and the effects of individual fibers on the microbiome.

CELL HOST & MICROBE (2022)

Review Food Science & Technology

A critical review on interplay between dietary fibers and gut microbiota

Shuxin Ye et al.

Summary: This review provides a detailed classification of dietary fibers, their impact on gut microbiota, and the results of relevant studies. A diet rich in dietary fiber and whole grains can improve the gut environment and promote host health.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2022)

Article Medicine, Research & Experimental

Dietary Influences on Gut Microbiota with a Focus on Metabolic Syndrome

Minu S. Thomas et al.

Summary: There is a clear correlation between gut microbiota, diet, and metabolic outcomes. A diet high in fiber can decrease inflammation and increase insulin sensitivity, while a diet high in fat and sugar can lead to dyslipidemia, insulin resistance, and low-grade inflammation. Unhealthy diets can alter the gut microbiota, disrupt the intestinal barrier, and contribute to the development of metabolic syndrome (MetS), while healthy diets can improve gut barrier function and reduce low-grade inflammation.

METABOLIC SYNDROME AND RELATED DISORDERS (2022)

Review Biochemistry & Molecular Biology

Dietary carbohydrates: Pathogenesis and potential therapeutic targets to obesity-associated metabolic syndrome

Salima Akter et al.

Summary: This article summarizes the common pathophysiology of metabolic syndrome and its relationship with carbohydrates, intrauterine nutrition, genetic predisposition, lifestyle factors, and treatment methods. It emphasizes the importance of dietary carbohydrates as key factors in the etiology and therapeutic targets of obesity and metabolic syndrome.

BIOFACTORS (2022)

Article Multidisciplinary Sciences

Dietary fiber intake and metabolic syndrome in postmenopausal African American women with obesity

Krista Lepping et al.

Summary: Fiber intake may be associated with lower risk of metabolic syndrome among postmenopausal African American women with obesity.

PLOS ONE (2022)

Review Nutrition & Dietetics

Associations between dietary fiber intake and cardiovascular risk factors: An umbrella review of meta-analyses of randomized controlled trials

Lingmeng Fu et al.

Summary: This umbrella meta-analysis evaluated the effects of dietary fiber intake on glycemic control, lipid profiles, systematic inflammation, and blood pressure. The results showed that higher dietary fiber intake was associated with improvements in these factors.

FRONTIERS IN NUTRITION (2022)

Review Nutrition & Dietetics

Therapeutic Benefits and Dietary Restrictions of Fiber Intake: A State of the Art Review

Corina-Bianca Ionita-Mindrican et al.

Summary: Fiber intake plays a crucial role in health and high-fiber foods have been shown to reduce the risk of disease. This article provides information on global fiber consumption, fiber metabolism, and the various health benefits associated with fiber intake.

NUTRIENTS (2022)

Review Nutrition & Dietetics

Dietary Fibre Modulates the Gut Microbiota

Peter Cronin et al.

Summary: Dietary fiber is crucial for nutrition and health, but modern dietary practices have led to a decrease in fiber consumption, potentially contributing to the rise of gut diseases. Changes in gut microbiota composition and function due to different types of dietary fiber could alter glucose and lipid metabolism.

NUTRIENTS (2021)

Review Gastroenterology & Hepatology

G-Protein-Coupled Receptors Are Dynamic Regulators of Digestion and Targets for Digestive Diseases

Meritxell Canals et al.

GASTROENTEROLOGY (2019)

Article Nutrition & Dietetics

Dietary Fiber, Atherosclerosis, and Cardiovascular Disease

Ghada A. Soliman

NUTRIENTS (2019)

Review Peripheral Vascular Disease

The Global Epidemic of the Metabolic Syndrome

Mohammad G. Saklayen

CURRENT HYPERTENSION REPORTS (2018)

Review Gastroenterology & Hepatology

Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases

Mingming Sun et al.

JOURNAL OF GASTROENTEROLOGY (2017)

Review Health Care Sciences & Services

Fiber supplements and clinically proven health benefits: How to recognize and recommend an effective fiber therapy

Kellen V. Lambeau et al.

JOURNAL OF THE AMERICAN ASSOCIATION OF NURSE PRACTITIONERS (2017)

Review Gastroenterology & Hepatology

Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism

Douglas J. Morrison et al.

GUT MICROBES (2016)

Review Endocrinology & Metabolism

The role of short chain fatty acids in appetite regulation and energy homeostasis

C. S. Byrne et al.

INTERNATIONAL JOURNAL OF OBESITY (2015)