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Updates in Parkinson's Disease Integrative Therapies: an Evidence-Based Review

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Article Geriatrics & Gerontology

A Pilot Study of Telehealth Mindfulness-Based Cognitive Therapy for Depression in Parkinson's Disease

Alejandro Interian et al.

Summary: This study evaluated the feasibility and effect of a telehealth mindfulness-based cognitive therapy intervention for Parkinson's disease (PD). The results showed that the intervention was feasible and beneficial, leading to improvements in depression, anxiety, and quality of life. Further research is needed to evaluate the intervention with a more diverse population.

JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY (2023)

Article Neurosciences

Art therapy as a comprehensive complementary treatment for Parkinson's disease

Tom Ettinger et al.

Summary: Parkinson's disease is a common neurodegenerative disease, and art therapy is a complementary therapy that promotes overall well-being through motor action and visuospatial processing. It allows the expression of complex psychological and somatic phenomena in nonverbal form, providing relief and positive change through exploration and understanding.

FRONTIERS IN HUMAN NEUROSCIENCE (2023)

Article Gastroenterology & Hepatology

Effect of probiotic supplementation on gastrointestinal motility, inflammation, motor, non-motor symptoms and mental health in Parkinson's disease: a meta-analysis of randomized controlled trials

Jong Mi Park et al.

Summary: This systematic review and meta-analysis study suggests that probiotics may improve motor and non-motor symptoms in Parkinson's disease patients and reduce depression. However, there is no significant improvement in constipation, antioxidant capacity, and risk of dyslipidemia. Probiotic capsules are more effective in improving gastrointestinal motility compared to fermented milk. Further research is needed to determine the mechanism of action of probiotics and optimal treatment protocols.

GUT PATHOGENS (2023)

Article Neurosciences

The effects of Mediterranean diet on severity of disease and serum Total Antioxidant Capacity (TAC) in patients with Parkinson's disease: a single center, randomized controlled trial

Zamzam Paknahad et al.

Summary: This study found that the Mediterranean Diet has positive effects on Parkinson's disease patients, as it significantly increases serum antioxidant capacity and lowers disease severity. However, further research is needed to confirm these findings.

NUTRITIONAL NEUROSCIENCE (2022)

Article Clinical Neurology

Aerobic Exercise Alters Brain Function and Structure in Parkinson's Disease: A Randomized Controlled Trial

Martin E. Johansson et al.

Summary: This study conducted a clinical trial and found that aerobic exercise can improve motor symptoms and cognitive control in patients with Parkinson's disease. It also showed positive effects on the structural and functional changes in the brain, suggesting that aerobic exercise can stabilize disease progression in the corticostriatal sensorimotor network.

ANNALS OF NEUROLOGY (2022)

Article Geriatrics & Gerontology

Acceptability and Feasibility of a Mindfulness Intervention Delivered via Videoconferencing for People With Parkinson's

Angeliki Bogosian et al.

Summary: The study aimed to reduce anxiety and depression for people with Parkinson's through online mindfulness intervention, but the results did not show significant effects in primary or secondary outcome measures. However, participants did experience an increase in quality of life, and qualitative study indicated that mindfulness is an appropriate and acceptable intervention.

JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY (2022)

Article Geriatrics & Gerontology

Combined effects of virtual reality techniques and motor imagery on balance, motor function and activities of daily living in patients with Parkinson's disease: a randomized controlled trial

Muhammad Kashif et al.

Summary: This study suggests that combining virtual reality and motor imagery techniques with routine physical therapy can significantly improve motor function, balance, and activities of daily living in patients with Parkinson's disease.

BMC GERIATRICS (2022)

Review Neurosciences

Benefits of Tango Therapy in Alleviating the Motor and Non-Motor Symptoms of Parkinson's Disease Patients-A Narrative Review

Any Docu Axelerad et al.

Summary: This study examines the effectiveness of tango therapy on motor and non-motor symptoms in Parkinson's disease based on articles published from 1980 to 2022. The study summarizes the advantages of tango in rehabilitating both motor and non-motor symptoms of Parkinson's disease. It highlights the need for more research to determine if tango can be a useful supplementary therapy for Parkinson's disease.

BRAIN SCIENCES (2022)

Article Neurosciences

Probiotics synergized with conventional regimen in managing Parkinson's disease

Hairong Sun et al.

Summary: The study found that co-administration of the probiotic Probio-M8 can improve sleep quality, alleviate anxiety, and gastrointestinal symptoms in patients with Parkinson's disease. It also has an impact on the host's gut microbiome, gut microbial metabolic potential, and serum metabolites.

NPJ PARKINSONS DISEASE (2022)

Article Psychology, Multidisciplinary

Effects of Mindfulness Yoga Versus Conventional Physical Exercises on Symptom Experiences and Health-related Quality of Life in People with Parkinson's Disease: The Potential Mediating Roles of Anxiety and Depression

Jojo Yan Yan Kwok et al.

Summary: This study compared the effects of mindfulness yoga and conventional stretching exercises on people with Parkinson's disease (PD) and found that mindfulness yoga was more effective in improving nonmotor and motor symptoms. Reduced anxiety and depression mediated the positive effects of mindfulness yoga.

ANNALS OF BEHAVIORAL MEDICINE (2022)

Article Sport Sciences

Dance Rhythms Improve Motor Symptoms in Individuals with Parkinson's Disease: A Randomized Clinical Trial

Jessica Amaro Moratelli et al.

Summary: This study found that dance protocols involving binary and quaternary rhythms can positively influence the motor symptoms of individuals with Parkinson's disease, specifically improving balance, gait, and mobility.

JOURNAL OF DANCE MEDICINE & SCIENCE (2022)

Article Clinical Neurology

Dance classes improve self-esteem and quality of life in persons with Parkinson's disease

Wya Feenstra et al.

Summary: This study found that dance classes can improve self-esteem, quality of life, and motor symptoms in persons with Parkinson's disease. This finding has significant implications for exploring the effectiveness and importance of dance as a complementary treatment option for Parkinson's disease.

JOURNAL OF NEUROLOGY (2022)

Article Clinical Neurology

Probiotics for constipation and gut microbiota in Parkinson's disease

Yitong Du et al.

Summary: This study suggests that probiotic treatment can effectively improve constipation symptoms in Parkinson's disease patients and have a positive impact on the gut microbiota.

PARKINSONISM & RELATED DISORDERS (2022)

Review Nutrition & Dietetics

The Role of Diet and Dietary Patterns in Parkinson's Disease

Emily Knight et al.

Summary: While diet and dietary patterns play a significant role in reducing the risk of PD or alleviating PD severity, inconsistent results and the need for further evidence highlight the necessity for more research before making dietary recommendations. Studies on the potential beneficial effects of dietary patterns on PD should also consider potential risks.

NUTRIENTS (2022)

Article Rehabilitation

Effects of Task-Based LSVT-BIG Intervention on Hand Function, Activity of Daily Living, Psychological Function, and Quality of Life in Parkinson's Disease: A Randomized Control Trial

YoungSeok Choi et al.

Summary: This study investigated the effects of a task-based LSVT-BIG intervention on hand function, ADL, psychological function, and quality of life in Parkinson's disease patients. The results showed that this intervention can significantly improve hand function, ADL, and reduce depression and anxiety in patients.

OCCUPATIONAL THERAPY INTERNATIONAL (2022)

Article Medicine, General & Internal

Effectiveness of Acupuncture for Anxiety Among Patients With Parkinson Disease A Randomized Clinical Trial

Jing-Qi Fan et al.

Summary: This study found acupuncture to be an effective treatment for anxiety in patients with Parkinson's disease, suggesting its potential in improving the well-being of these patients.

JAMA NETWORK OPEN (2022)

Review Health Care Sciences & Services

Effectiveness of Acupuncture in Parkinson's Disease Symptoms-A Systematic Review

Catarina Ramos Pereira et al.

Summary: This systematic review aimed to evaluate the effectiveness of acupuncture treatments in relieving Parkinson's disease symptoms. The study found positive effects of acupuncture in improving motor and non-motor symptoms, but the discrepancies in study design and methodology make it difficult to compare the results.

HEALTHCARE (2022)

Article Integrative & Complementary Medicine

Home-Based Walking Meditation Decreases Disease Severity in Parkinson's Disease: A Randomized Controlled Trial

Witoon Mitarnun et al.

Summary: Walking meditation has positive effects on functional performance and anxiety in Parkinson's disease, reducing disease severity and anxiety symptoms.

JOURNAL OF INTEGRATIVE AND COMPLEMENTARY MEDICINE (2022)

Article Clinical Neurology

Impact of Isolation During the COVID-19 Pandemic on the Patient Burden of Parkinson's Disease: A PMD Alliance Survey

Neal Hermanowicz et al.

Summary: The survey indicated that decreased social support from outside of the household during the COVID-19 pandemic was significantly associated with increased burden of mood and non-motor symptoms of PD.

NEUROPSYCHIATRIC DISEASE AND TREATMENT (2022)

Review Psychology, Clinical

The effectiveness of psychological interventions for loneliness: A systematic review and meta-analysis

Nisha Hickin et al.

Summary: The study found that psychological interventions for loneliness are effective, particularly in the face of increased loneliness due to the COVID-19 pandemic. However, there was considerable heterogeneity in the effectiveness of the interventions, suggesting that future research should further explore the effectiveness of interventions and consider personalizing psychological treatment.

CLINICAL PSYCHOLOGY REVIEW (2021)

Review Integrative & Complementary Medicine

Tai Chi and Qi Gong therapies as a complementary treatment in Parkinson's disease - a systematic review

Anna Kamieniarz et al.

COMPLEMENTARY THERAPIES IN MEDICINE (2021)

Article Clinical Neurology

MIND and Mediterranean Diets Associated with Later Onset of Parkinson's Disease

Avril Metcalfe-Roach et al.

Summary: This study found a strong correlation between adherence to the MIND diet and age of onset of Parkinson's disease, especially in female patients. Additionally, adherence to the Greek Mediterranean diet was also associated with later onset of PD.

MOVEMENT DISORDERS (2021)

Article Clinical Neurology

Art therapy for Parkinson ? s disease

Alberto Cucca et al.

Summary: This study aimed to investigate the rehabilitative effect of art therapy in Parkinson's disease patients and found that art therapy improved visual-cognitive skills and motor function in these patients, resulting in functional reorganization of visual networks in the brain.

PARKINSONISM & RELATED DISORDERS (2021)

Article Environmental Sciences

Dual-Task-Based Drum Playing with Rhythmic Cueing on Motor and Attention Control in Patients with Parkinson's Disease: A Preliminary Randomized Study

Jin-Kyoung Park et al.

Summary: This study evaluated the effects of drum playing with rhythmic cueing on upper extremity motor control and attention control in patients with Parkinson's disease. The results showed significant improvements in sustained time of entrainment, latency time until entrainment, and cognitive measures in the intervention group. Drum playing with rhythmic cueing has great potential to improve motor control and attention in patients with Parkinson's disease.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

Article Health Care Sciences & Services

Effect of clinical Pilates training on balance and postural control in patients with Parkinson's disease: a randomized controlled trial

Fahriye Coban et al.

Summary: Clinical Pilates exercises were found to be as effective as conventional physiotherapy exercises in improving balance and postural control in Parkinson's disease patients. However, the Clinical Pilates group showed significant improvement in dynamic balance values compared to the conventional physiotherapy group.

JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH (2021)

Article Clinical Neurology

Effectiveness of a dance-physiotherapy combined intervention in Parkinson's disease: a randomized controlled pilot trial

Elisa Frisaldi et al.

Summary: The study demonstrated that the DArT method was more effective than conventional physiotherapy in improving motor impairment in mild PD patients, and was found to be safe and well accepted. The experimental group showed significant improvements in MDS-UPDRS-III scores and upper body subscores, while conventional physiotherapy had better effects on reducing trait anxiety levels.

NEUROLOGICAL SCIENCES (2021)

Article Clinical Neurology

High intensity aerobic exercise improves bimanual coordination of grasping forces in Parkinson's disease

Elizabeth Jansen et al.

Summary: High intensity aerobic exercise, whether forced or voluntary, significantly improves symptoms and manual dexterity in PD patients by enhancing connectivity between basal ganglia and cortical areas, leading to improved motor control and execution abilities.

PARKINSONISM & RELATED DISORDERS (2021)

Article Orthopedics

Physical Activity in De Novo Parkinson Disease: Daily Step Recommendation and Effects of Treadmill Exercise on Physical Activity

Reed Handlery et al.

Summary: People with Parkinson's disease are encouraged to take at least 4200 steps per day to meet physical activity guidelines through walking. High-intensity treadmill exercise was found to increase daily steps and moderate- to vigorous-intensity physical activity in individuals with Parkinson's disease, but these changes were not associated with improvements in fitness levels.

PHYSICAL THERAPY (2021)

Review Public, Environmental & Occupational Health

Social and psychological impact of the COVID-19 pandemic on people with Parkinson's disease: a scoping review

S. K. Brooks et al.

Summary: The COVID-19 pandemic adversely affected the social and psychological well-being of people with Parkinson's disease, impacting their physical and mental health, access to healthcare, daily and social activities, as well as caregivers. Disruption of healthcare services, loss of usual activities and supports, and reduction in physical activity contributed to these negative effects.

PUBLIC HEALTH (2021)

Article Medicine, General & Internal

Effect of a Mediterranean diet intervention on gastrointestinal function in Parkinson's disease (the MEDI-PD study): study protocol for a randomised controlled trial

Carley Rusch et al.

Summary: This study aims to investigate the therapeutic effects of the Mediterranean diet on constipation symptoms in PD patients. Using a randomized controlled parallel study design, the primary outcome includes evaluating the change in GSRS constipation syndrome scores. Secondary outcomes encompass assessing multiple indicators such as stool frequency, form, dietary intake, and quality of life.

BMJ OPEN (2021)

Review Neurosciences

Acupuncture for Parkinson's Disease: Efficacy Evaluation and Mechanisms in the Dopaminergic Neural Circuit

Yadan Zhao et al.

Summary: Acupuncture may be beneficial for PD treatment, particularly in early stages by reducing neurodegeneration of dopaminergic neurons and delaying disease progression, as well as protecting neurons through modulating dopamine circuit balance. However, further verification of its benefits is needed through basic and clinical studies.

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Effectiveness of a Long-Term, Home-Based Aerobic Exercise Intervention on Slowing the Progression of Parkinson Disease: Design of the Cyclical Lower Extremity Exercise for Parkinson Disease II (CYCLE-II) Study

Jay L. Alberts et al.

Summary: This study aims to investigate the effects of long-term high-intensity aerobic exercise on the progression of Parkinson's disease and to develop a prognostic model for patients undergoing aerobic exercise intervention. The research will assess upper and lower limb motor function as well as non-motor function through monitoring daily activities, clinical, and biomechanical measures.

PHYSICAL THERAPY (2021)

Article Psychology, Experimental

Yoga Meditation Enhances Proprioception and Balance in Individuals Diagnosed With Parkinson's Disease

Nicholas P. Cherup et al.

Summary: This study compared the effectiveness of two proprioceptive exercise programs for Parkinson's disease patients and found that a yoga meditation program showed significant improvements in balance assessment and joint kinesthesia. This indicates that mind-body techniques like yoga may be beneficial for improving movement control and body awareness in this population.

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Outcome of Parkinson's Disease Patients Affected by COVID-19

Angelo Antonini et al.

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A Randomized, Controlled Trial of Exercise for Parkinsonian Individuals With Freezing of Gait

Carla Silva-Batista et al.

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Social Prescribing - Transforming the Relationship between Physicians and Their Patients

Martin Roland et al.

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Traditional Indigenous medicine in North America: A scoping review

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A Common Elements Approach to the Development of a Modular Cognitive Behavioral Theory for Chronic Loneliness

Anton Kall et al.

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Lonesome no more? A two-year follow-up of internet-administered cognitive behavioral therapy for loneliness

Anton Kall et al.

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Walking to your right music: a randomized controlled trial on the novel use of treadmill plus music in Parkinson's disease

Rocco Salvatore Calabro et al.

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Sleep Disturbance as Potential Risk and Progression Factor for Parkinson's Disease

Nicolaas Bohnen et al.

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Exercise increases caudate dopamine release and ventral striatal activation in Parkinson's disease

Matthew A. Sacheli et al.

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Low-Fat Versus Ketogenic Diet in Parkinson's Disease: A Pilot Randomized Controlled Trial

Matthew C. L. Phillips et al.

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Some excerpts from Charaka Samhita - An ancient treatise on Ayurveda & healthy living

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