期刊
CHEMICAL COMMUNICATIONS
卷 51, 期 2, 页码 362-365出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc07453j
关键词
-
资金
- National Cancer Institute, National Institutes of Health [R00CA127161, R01CA182543]
- Purdue Center for Cancer Research (through an Innovative Pilot Project Award)
A novel time-resolved luminescence biosensor assay for anaplastic lymphoma kinase (ALK) was developed. We used a straightforward strategy to modify a known ALK substrate into a peptide biosensor that can accommodate terbium luminescence sensitization upon its phosphorylation by ALK. Since this strategy is generalizable, this high-throughput screening compatible assay serves as an example for development of other kinase assays that employ terbium luminescence as a read-out.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据