Dendrimer-encapsulated Pt nanoparticles with peroxidase-mimetic activity as biocatalytic labels for sensitive colorimetric analyses

We demonstrate the feasible use of Pt nanoparticles encapsulated inside amine-terminated fourth-generation polyamidoamine dendrimers as peroxidase-mimetic labels for sensitive colorimetric assays. This was performed by utilizing intrinsic dual functionalities of the dendrimer-encapsulated Pt nanoparticles, i.e. peroxidase-like activity and multiple conjugation sites.