Enantioselective adsorption in homochiral metal-organic frameworks: the pore size influence

Uptake experiments in thin films of isoreticular chiral MOFs of type Cu-2(Dcam)(2)(L) with identical stereogenic centers but different pore dimensions show that the enantioselectivity is significantly influenced by the pore size. The highest selectivity was found for medium pore sizes, roughly corresponding to the extension of the chiral guest molecule, limonene.