期刊
CHEMICAL COMMUNICATIONS
卷 51, 期 34, 页码 7386-7389出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc01601k
关键词
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资金
- national 973'' program [2014CB932002]
- National medical research council [NMRC/CBRG/0015/2012]
- Natural Science Foundation of China [11105150]
- NGS scholarship
A 241-membered cyanine-based library was constructed by the combinatorial chemistry strategy. Combined with high-throughput screening, we successfully discovered a novel fluorescent probe (CyC-M716) capable of identifying a subset of parallel G-quadruplexes with propeller loops stretching across three tetrad layers with high sensitivity and selectivity.
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