期刊
CHEMICAL COMMUNICATIONS
卷 51, 期 39, 页码 8307-8310出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc01880c
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资金
- Natural Sciences and Engineering Research Council of Canada (NSERC)
- National Institute for Nanotechnology (NINT)
Sample cleanup is a major processing step in many analytical assays. Here, we propose an approach to capture-and-release of analytes based on the DNA strand displacement reaction (SDR) and demonstrate its application to a fluoroimmunoassay on beads for a thyroid cancer biomarker, thyroglobulin. The SDR-based cleanup showed no interference from matrix molecules in serum.
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