Hydroxylamine-O-sulfonic acid as an efficient coreactant for luminol chemiluminescence for selective and sensitive detection

Hydroxylamine-O-sulfonic acid, a versatile reagent for organic synthesis, has been explored as an effective coreactant for luminol chemiluminescence. Co2+ can dramatically enhance the chemiluminescence of this system. The sensitive detection of Co2+, luminol and HOSA, including highly selective Co2+ detection, is achieved.