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Article
Public, Environmental & Occupational Health
Kevin S. Shah et al.
Summary: This study examines the disparities in clinical trial enrollment among COVID-19 hospitalized patients, revealing that female and Black patients are less likely to be enrolled compared to men and other racial groups.
JOURNAL OF RACIAL AND ETHNIC HEALTH DISPARITIES
(2023)
Review
Medicine, Research & Experimental
Alyssa M. Vanderbeek et al.
Summary: During the pandemic, there has been a surge in the number of platform trials compared to historical use. While transparency in statistical methods and clarity of data sharing policies needs improvement, platform trials appear particularly well-suited for rapid evidence generation. Trials secured funding quickly and many succeeded in adding new therapies in a short time period, thus demonstrating the potential for these trial designs to be implemented beyond the pandemic. The evidence gathered here may provide ample insight to further inform operational, statistical, and regulatory aspects of future platform trial conduct.
CONTEMPORARY CLINICAL TRIALS
(2022)
Article
Health Care Sciences & Services
Noah Goodson et al.
Summary: Traditional clinical trials often fail to recruit representative participant populations. Decentralized clinical trials (DCTs) have been proposed as a potential solution to reduce barriers and attract a wider range of participants, but their impact on participant inclusivity remains to be seen. Digital studies aiming to address a single element of inclusion may inadvertently lead to unintended consequences in other areas. Implementing DCTs presents new challenges such as the digital divide and the need to build new infrastructure.
NPJ DIGITAL MEDICINE
(2022)
Review
Microbiology
Amy L. Leber et al.
Summary: The COVID pandemic has highlighted the importance of laboratory medicine and the critical shortage of trained laboratory personnel. The need for laboratory professionals is expected to grow by 11% by 2030. Proposed actions to address this issue include increasing awareness of the medical laboratory science profession and providing more training opportunities. Recent survey data shows that 80% of microbiology laboratories have vacant positions due to a lack of qualified applicants.
JOURNAL OF CLINICAL MICROBIOLOGY
(2022)
Editorial Material
Medicine, General & Internal
Janet Woodcock et al.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
News Item
Biotechnology & Applied Microbiology
Kevin Bugin et al.
NATURE REVIEWS DRUG DISCOVERY
(2021)
Letter
Medicine, General & Internal
Ye Eun (Grace) Jung et al.
JAMA INTERNAL MEDICINE
(2021)
Article
Computer Science, Information Systems
Melissa A. Haendel et al.
Summary: N3C is an open science community focused on analyzing patient-level data from multiple centers to address the challenges posed by COVID-19. By overcoming technical, regulatory, policy, and governance barriers, N3C has successfully established a secure data enclave for efficient, transparent, and reproducible collaborative analytics.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2021)
Biographical-Item
Biotechnology & Applied Microbiology
Walter Orenstein
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2019)
Editorial Material
Medicine, General & Internal
Adrian F. Hernandez et al.
ANNALS OF INTERNAL MEDICINE
(2015)
