4.4 Article

Reduced myocardial work in asymptomatic heavy alcohol use and its correlation with epicardial adipose tissue volume and serum biomarkers

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

The Role of VEGF Family in Lipid Metabolism

Yan Zhou et al.

Summary: The VEGF family plays a major role in tumors and ophthalmic diseases, and also has potential in regulating lipids. Factors like VEGF-A and VEGF-C have been shown to regulate lipid absorption by affecting chylous ducts. Other effects, such as regulating LPL, EL, and SDC1, have also been confirmed. Further research is needed to understand the concrete mechanisms and apply them in clinical settings. The VEGF family may have specific ways to treat dyslipidemia and contribute to the treatment of other metabolic diseases like diabetes and obesity.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2023)

Article Cardiac & Cardiovascular Systems

Global Myocardial Work Combined with Treadmill Exercise Stress to Detect Significant Coronary Artery Disease

Jingru Lin et al.

Summary: The study investigates the use of global myocardial work (MW) combined with treadmill exercise stress to detect significant coronary artery disease (CAD) in patients with angina pectoris. The results show that peak global work efficiency (GWE) and recovery global wasted work (GWW) can predict significant CAD. A model combining peak GWE and recovery GWW performs better in identifying significant CAD compared to peak GWE alone. Overall, global MW parameters combined with exercise stress serve as an accurate noninvasive screening method before invasive diagnostic techniques.

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY (2022)

Article Cardiac & Cardiovascular Systems

Left ventricular and atrial remodelling in hypertensive patients using thresholds from international guidelines and EMINCA data

Yuanyuan Sheng et al.

Summary: The study aimed to investigate differences in the prevalence of left ventricular and left atrial remodeling in hypertensive patients using various thresholds and indexing methods. It found that using echocardiographic thresholds and indexing methods recommended by guidelines may lead to significant misdiagnosis of LA dilatation and abnormal LV geometry in Chinese patients with hypertension.

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING (2022)

Review Neurosciences

Adipose-related microRNAs as modulators of the cardiovascular system: the role of epicardial adipose tissue

Diana Santos et al.

Summary: Epicardial adipose tissue (EAT) is a unique subtype of visceral adipose tissue located on the surface of the heart, influencing the metabolic and immune function of cardiomyocytes and coronary arteries. Dysregulation of specific microRNAs has been found to contribute to dysfunction in cardiac and vascular function.

JOURNAL OF PHYSIOLOGY-LONDON (2022)

Review Cardiac & Cardiovascular Systems

Epicardial adipose tissue in contemporary cardiology

Gianluca Iacobellis

Summary: There is growing interest in the role of epicardial adipose tissue (EAT) in cardiovascular disease. EAT has a protective effect on the myocardium through thermogenic function and can also be harmful by secreting inflammatory and fibrotic cytokines. EAT may also be involved in COVID-19-related cardiac syndrome. It is a modifiable risk factor that can be assessed using different imaging techniques.

NATURE REVIEWS CARDIOLOGY (2022)

Article Public, Environmental & Occupational Health

The burden of alcoholic cardiomyopathy in China and different regions around the world

Jing Zhang et al.

Summary: The burden of alcoholic cardiomyopathy (ACM) has significantly increased in China and globally from 1990 to 2019. The highest burden is seen in high-middle socio-demographic index (SDI) regions, particularly among men aged 50-69 years old. Tailored strategies based on geography and gender-age are needed to prevent ACM.

JOURNAL OF GLOBAL HEALTH (2022)

Article Environmental Sciences

Long-term exposure to ozone and cardiovascular mortality in China: a nationwide cohort study

Yue Niu et al.

Lancet Planetary Health (2022)

Article Cardiac & Cardiovascular Systems

Incremental prognostic value of global myocardial work over ejection fraction and global longitudinal strain in patients with heart failure and reduced ejection fraction

Chun-Li Wang et al.

Summary: This study found that in patients with reduced EF, global myocardial work (GMW) can provide incremental prognostic information over EF and GLS, helping to identify patients at risk for all-cause death and HF hospitalization.

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING (2021)

Editorial Material Cardiac & Cardiovascular Systems

The diverging role of epicardial adipose tissue in heart failure with reduced and preserved ejection fraction: not all fat is created equal

Jasper Tromp et al.

EUROPEAN JOURNAL OF HEART FAILURE (2021)

Editorial Material Cardiac & Cardiovascular Systems

How to measure left ventricular myocardial work by pressure-strain loops

Otto A. Smiseth et al.

Summary: Myocardial work, calculated through non-invasive measures of left ventricular pressure and strain, provides diagnostic information beyond traditional indicators such as ejection fraction and strain by considering afterload and efficiency. This method can evaluate both global and segmental myocardial work, and has shown clinical value in patient selection for cardiac resynchronization therapy, with several other applications currently being tested.

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING (2021)

Article Cardiac & Cardiovascular Systems

Myocardial work in Stage 1 and 2 hypertensive patients

Akshar Jaglan et al.

Summary: The study aimed to distinguish patterns of LV response in hypertensive vs. non-hypertensive patients using MW analysis. Results showed differences in GWI, GCW, and GWW between control and hypertension groups, indicating MW as an advanced assessment of LV systolic function in hypertensive patients under increased afterload conditions. This suggests MW provides a closer look at the relationship between LV pressure and contractility compared to traditional parameters like LV ejection fraction and global longitudinal strain.

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING (2021)

Article Peripheral Vascular Disease

Accurate Prediction of Total PlGF (Placental Growth Factor) From Free PlGF and sFlt-1 (Soluble Fms-Like Tyrosine Kinase-1): Evidence for Markedly Elevated PlGF Levels in Women With Acute Fatty Liver of Pregnancy

Rugina Neuman et al.

Summary: The study indicates that PlGF production is significantly upregulated in AFLP patients, mainly originating from the placenta. Compared to other disease groups, AFLP patients have significantly elevated levels of PlGF, which rapidly decline postpartum.

HYPERTENSION (2021)

Article Cell Biology

Secretory products from epicardial adipose tissue induce adverse myocardial remodeling after myocardial infarction by promoting reactive oxygen species accumulation

Shuang Hao et al.

Summary: This study identified a new pathological mechanism involving an EAT/miRNA axis that explains the adverse myocardial remodeling occurring after myocardial infarction. The findings showed that miR-134-5p knockdown limited adverse myocardial remodeling in a rat model of MI by alleviating cardiomyocyte hypertrophy and fibrosis.

CELL DEATH & DISEASE (2021)

Article Cardiac & Cardiovascular Systems

Characteristics of subjects with alcoholic cardiomyopathy and sudden cardiac death

Siiri Hietanen et al.

Article Cardiac & Cardiovascular Systems

Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation

Jordi Heijman et al.

CIRCULATION RESEARCH (2020)

Review Gastroenterology & Hepatology

Effect of ethanol on lipid metabolism

Min You et al.

JOURNAL OF HEPATOLOGY (2019)

Review Cardiac & Cardiovascular Systems

Epicardial adipose tissue and cardiovascular diseases

Anna Maria Ansaldo et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2019)

Article Cardiac & Cardiovascular Systems

Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation

Chunxia Yao et al.

CIRCULATION (2018)

Review Cardiac & Cardiovascular Systems

Epicardial Adipose Tissue May Mediate Deleterious Effects of Obesity and Inflammation on the Myocardium

Milton Packer

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)

Review Medicine, General & Internal

Alcoholic cardiomyopathy: What is known and what is not known

Antonio Mirijello et al.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2017)

Article Cardiac & Cardiovascular Systems

Echocardiographic Measurements in Normal Chinese Adults Focusing on Cardiac Chambers and Great Arteries: A Prospective, Nationwide, and Multicenter Study

Gui-Hua Yao et al.

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY (2015)

Review Medicine, General & Internal

Alcohol and Cardiovascular Health: The Dose Makes the Poison . . . or the Remedy

James H. O'Keefe et al.

MAYO CLINIC PROCEEDINGS (2014)

Article Endocrinology & Metabolism

Effect of vascular endothelial growth factor receptor 2 antagonism on adiposity in obese mice

H. Roger Lijnen et al.

JOURNAL OF MOLECULAR ENDOCRINOLOGY (2013)

Article Medicine, General & Internal

Angiogenesis and biomarkers of cardiovascular risk in adults with metabolic syndrome

M. Siervo et al.

JOURNAL OF INTERNAL MEDICINE (2010)

Article Cardiac & Cardiovascular Systems

Elevated placental growth factor levels are associated with adverse outcomes at four-year follow-up in patients with acute coronary syndromes

T Lenderink et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2006)