☆ 4.8 Editorial Material

FDA Modernization Act 2.0 Paves the Way to Computational Biology and Clinical Trials in a Dish

CIRCULATION (2023)

2022 FDA approvals

Asher Mullard

Summary: In 2022, the FDA approved 37 new drugs, the lowest number to pass regulatory scrutiny since 2016.

NATURE REVIEWS DRUG DISCOVERY (2023)

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Review Engineering, Biomedical

Shifting machine learning for healthcare from development to deployment and from models to data

Angela Zhang et al.

Summary: This article discusses the use of deep generative models, federated learning, and transformer models in the deployment of machine learning for healthcare. From model development to model deployment, data plays a central role. The article provides a comprehensive overview of the innovations and challenges in healthcare machine learning, with a focus on data-centric perspective.

NATURE BIOMEDICAL ENGINEERING (2022)

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Article Biochemical Research Methods

Challenges and opportunities for the next generation of cardiovascular tissue engineering

Sangkyun Cho et al.

Summary: This Perspective discusses the technologies and challenges in cardiac tissue engineering, and proposes strategies to overcome these challenges. Engineered cardiac tissues derived from human induced pluripotent stem cells offer unique opportunities for personalized disease modeling, drug discovery, and cardiac repair. However, there are still major obstacles to be addressed before the field can move towards commercial and clinical translation.

NATURE METHODS (2022)

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Article Cell Biology

Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy

Nazish Sayed et al.

SCIENCE TRANSLATIONAL MEDICINE (2020)

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FDA Modernization Act 2.0 Paves the Way to Computational Biology and Clinical Trials in a Dish

相关参考文献

2022 FDA approvals

Shifting machine learning for healthcare from development to deployment and from models to data

Challenges and opportunities for the next generation of cardiovascular tissue engineering

Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy

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