Circular dichroism and UV-Vis detection of UV-induced damage to nucleic acids

Article Public, Environmental & Occupational Health

Catalytic Surgical Smoke Filtration Unit Reduces Formaldehyde Levels in a Simulated Operating Room Environment

Gregory T. Carroll et al.

Summary: Incorporating catalytic materials into air-purifying devices has the potential to reduce formaldehyde levels in healthcare settings.

ACS CHEMICAL HEALTH & SAFETY (2023)

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Article Chemistry, Physical

Intrinsic fluorescence of UV-irradiated DNA

Gregory T. Carroll et al.

Summary: In this study, it was found that both natural and synthetic DNA exhibit a fluorescent photoproduct upon UV irradiation. Calf thymus DNA and poly(dA).poly(dT) showed significant fluorescence after being exposed to UV light, while poly(dAdT)2 displayed fluorescence to a lesser degree. Poly(dGdC)2 did not exhibit fluorescence, but the UV-Vis data indicated photochemical changes. The results indicate that fluorescence occurs when thymine and adenine base pairs are present, and is enhanced when thymine nucleobases are adjacent to each other on the same strand.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY (2023)

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Article Orthopedics

Many Common Pathogens are Present in the Operative Room Air During Surgery

Emanuele Chisari et al.

Summary: This study assessed the sanitary measures of operating theaters and found that microbial organisms are commonly present in the operating room air during hip and knee arthroplasties and spine procedures.

JOURNAL OF ARTHROPLASTY (2022)

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Article

Discrete room pressure drops predict door openings and contamination levels in the operating room setting

Gregory T. Carroll et al.

Perioperative Care and Operating Room Management (2022)

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Article Public, Environmental & Occupational Health

Removal of SARS-CoV-2 bioaerosols using ultraviolet air filtration

Roy E. Barnewall et al.

Summary: Engineering controls are crucial in reducing the spread of SARS-CoV-2, with technologies like UV-C light and HEPA filtration being effective in removing the virus from the air. The study confirms the efficacy of an APS combining UV-C light and HEPA filtration in eliminating SARS-CoV-2 in a controlled environment.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2021)

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Article Multidisciplinary Sciences

Thymine dissociation and dimer formation: A Raman and synchronous fluorescence spectroscopic study

Anushka Nagpal et al.

Summary: The study investigated the effects of UV irradiation on thymine solutions using various spectroscopic methods, showing that thymine dimer formation and (6-4) photoproduct formation increase with radiation dose. Spectroscopic data revealed the mechanism of thymine dimer formation, which is known to inhibit DNA replication and cause bacterial inactivation.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

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Review Biochemistry & Molecular Biology

Air Disinfection for Airborne Infection Control with a Focus on COVID-19: Why Germicidal UV is Essential†

Edward A. Nardell

Summary: Aerosol transmission is recognized as the main way COVID-19 spreads, highlighting the importance of ventilation. Mechanical ventilation in non-healthcare settings may not achieve recommended air changes per hour. Upper room germicidal UV air disinfection is a key technology for reducing COVID-19 transmission.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2021)

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Article Oncology

Possibility of using ultraviolet radiation for disinfecting the novel COVID-19

Anil Kumar et al.

Summary: The article emphasizes the importance of using light-based technologies to disinfect the novel COVID-19 and identifies the benefits of repurposing ultraviolet light-based strategies to combat the emergence of the COVID-19 pandemic. It also proposes a possible design for ultraviolet irradiation.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2021)

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Article Chemistry, Medicinal