Recent advances in visible light-me diate d chemical transformations of enaminones

Enaminones, which possesses both the nucleophilic enamine as well as electrophilic enone structures, are well known versatile building blocks in organic synthesis. Meanwhile, visible light-mediated reac-tions have emerged as useful synthetic strategy with enhanced sustainability. Around the last decade, various photochemical transformations of enaminones have been developed to construct cyclic or acyclic compounds. In this review, we describe the recent advances in visible light-mediated chemical transfor-mations of enaminones. Detailed discussion on the reaction mechanism of the related reactions is given to provide guide to the reader. Finally, a summary on the existing challenges and the future outlook towards the development of practical photocatalytic reactions of enaminones is also presented. (c) 2023 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.

Automated summary

Enaminones, versatile building blocks in organic synthesis, possess both nucleophilic enamine and electrophilic enone structures. Visible light-mediated reactions have emerged as a sustainable and useful synthetic strategy, and have been successfully applied to construct cyclic or acyclic compounds from enaminones. This review describes the recent advances in visible light-mediated chemical transformations of enaminones, providing detailed discussion on reaction mechanisms to guide readers. A summary on existing challenges and future outlook towards practical photocatalytic reactions of enaminones is also presented.