期刊
CHEMISTRY & BIODIVERSITY
卷 -, 期 -, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.202300492
关键词
natural products; phytochemistry; Salicaceae; var; lingua; sylvestris
In this review, the chemical composition, content, pharmacological activities, and toxicity of the essential oils (EOs) from Casearia species were investigated. The EOs exhibited a wide range of bioactivities, including cytotoxicity, anti-inflammatory, antiulcer, antimicrobial, antidiabetic, antioxidant, antifungal, and antiviral activities. The main components associated with these activities were identified. However, data on the toxicity of these EOs are limited. Further investigation and exploitation of Casearia EOs are necessary.
Casearia species are found in the America, Africa, Asia, and Australia and present pharmacological activities, besides their traditional uses. Here, we reviewed the chemical composition, content, pharmacological activities, and toxicity of the essential oils (EOs) from Casearia species. The EO physical parameters and leaf botanical characteristics were also described. The bioactivities of the EOs from the leaves and their components include cytotoxicity, anti-inflammatory, antiulcer, antimicrobial, antidiabetic, antioxidant, antifungal, and antiviral activities. The main components associated with these activities are the & alpha;-zingiberene, (E)-caryophyllene, germacrene D, bicyclogermacrene, spathulenol, & alpha;-humulene, & beta;-acoradiene, and & delta;-cadinene. Data on the toxicity of these EOs are scarce in the literature. Casearia sylvestris Sw. is the most studied species, presenting more significant pharmacological potential. The chemical variability of EOs components was also investigated for this species. Caseria EOs have relevant pharmacological potential and must be further investigated and exploited.
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