Transition Metal-Catalyzed Enantioselective Synthesis of Chiral Five- and Six-Membered Benzo O-heterocycles

Enantiomerically enriched five- and six-membered benzo oxygen heterocycles are privileged architectures in functional organic molecules. Over the last several years, many effective methods have been established to access these compounds. However, comprehensive documents cover updated methodologies still in highly demand. In this review, recent transition metal catalyzed transformations lead to chiral five- and six-membered benzo oxygen heterocycles are presented. The mechanism and chirality transfer or control processes are also discussed in details.

Automated summary

This review presents recent transition metal catalyzed transformations for the synthesis of chiral five- and six-membered benzo oxygen heterocycles and discusses in detail the reaction mechanisms and processes for chirality transfer or control.